PMID- 32084091
OWN - NLM
STAT- MEDLINE
DCOM- 20210226
LR  - 20210226
IS  - 1549-8425 (Electronic)
IS  - 1549-8417 (Linking)
VI  - 16
IP  - 2
DP  - 2020 Jun
TI  - Safety and Clinical Outcomes of Hospital in the Home.
PG  - 123-129
LID - 10.1097/PTS.0000000000000617 [doi]
AB  - OBJECTIVES: The aim of the study was to evaluate clinical outcomes and adverse 
      events (AEs) experienced by patients treated within the Hospital in the Home 
      (HITH) service of a major metropolitan hospital in South Australia. METHODS: A 
      retrospective case note audit of 100 HITH episodes among adults who received 
      continuous intravenous antimicrobial therapy via an elastomeric or electronic 
      infusion device was undertaken. Age- and sex-adjusted binomial logistic 
      regression analyses were undertaken to identify factors associated with major and 
      minor AEs. RESULTS: Of the 100 patients included, 71 were male and the mean (SD) 
      patient age was 62.8 (17.19) years. Elastomeric infusion devices were used for 98 
      patients. The mean (SD) HITH treatment duration was 20.1 (11.9) days. Overall, 
      130 AEs were documented for 72 patients (72%), of whom 12 patients experienced a 
      major AE and 68 patients experienced a minor AE. There were 45 occasions among 23 
      patients where an infusion administered through an elastomeric device did not run 
      to completion. Fifteen patients were readmitted to hospital. Minor AEs were more 
      likely among people with more vascular line days (adjusted odds ratio [aOR] = 
      1.05; 95% confidence interval (CI) = 1.01-1.10 per day increase) and females (aOR 
      = 4.43; 95% CI = 1.14-17.17). An increased number of vascular line days was 
      associated with an increased likelihood of an incomplete infusion (aOR = 1.05; 
      95% CI = 1.01-1.09). Hospital readmission was more likely with increasing age 
      (aOR = 1.06; 95% CI = 1.01-1.11 per year increase). CONCLUSIONS: Adverse events 
      need to be monitored carefully when HITH treatment is provided for extended 
      periods.
FAU - Sriskandarajah, Shanthy
AU  - Sriskandarajah S
AD  - From the Medical Device Research Institute, College of Science and Engineering, 
      Flinders University, Adelaide, South Australia.
FAU - Ritchie, Brett
AU  - Ritchie B
AD  - Infectious Diseases Department, Women's and Children's Hospital, North Adelaide, 
      South Australia.
FAU - Eaton, Vaughn
AU  - Eaton V
AD  - SA Pharmacy, Southern Adelaide Local Health Network, Adelaide.
FAU - Sluggett, Janet K
AU  - Sluggett JK
FAU - Hobbs, Jodie G
AU  - Hobbs JG
AD  - From the Medical Device Research Institute, College of Science and Engineering, 
      Flinders University, Adelaide, South Australia.
FAU - Daniel, Santhosh
AU  - Daniel S
FAU - Reynolds, Karen J
AU  - Reynolds KJ
AD  - From the Medical Device Research Institute, College of Science and Engineering, 
      Flinders University, Adelaide, South Australia.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Patient Saf
JT  - Journal of patient safety
JID - 101233393
SB  - IM
MH  - Female
MH  - Home Care Services/*standards
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Patient Safety/*standards
MH  - Retrospective Studies
EDAT- 2020/02/23 06:00
MHDA- 2021/02/27 06:00
CRDT- 2020/02/22 06:00
PHST- 2020/02/23 06:00 [pubmed]
PHST- 2021/02/27 06:00 [medline]
PHST- 2020/02/22 06:00 [entrez]
AID - 01209203-202006000-00002 [pii]
AID - 10.1097/PTS.0000000000000617 [doi]
PST - ppublish
SO  - J Patient Saf. 2020 Jun;16(2):123-129. doi: 10.1097/PTS.0000000000000617.