PMID- 32084304
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20200420
LR  - 20200420
IS  - 1520-636X (Electronic)
IS  - 0899-0042 (Linking)
VI  - 32
IP  - 5
DP  - 2020 May
TI  - A green and effective method for the determination of metalaxyl enantiomers in 
      tobacco and soil by supercritical fluid chromatography-tandem mass spectrometry.
PG  - 505-514
LID - 10.1002/chir.23184 [doi]
AB  - We reported a new methodology for the stereoselective determination of metalaxyl 
      enantiomers in tobacco and soil. The QuEChERS (quick, easy, cheap, effective, 
      rugged, and safe) method was used for the extraction and clean-up of the tobacco 
      and soil samples. Separation of the metalaxyl enantiomers was performed on an 
      ACQUITY UPC2 Trefoil CEL1 chiral column coupled with supercritical fluid 
      chromatography with tandem mass spectrometry (SFC-MS/MS), and the run time was 
      only 5 minutes. Under the optimized conditions, the recoveries for the 
      enantiomers were between 78.2% and 93.3% with intraday relative standard 
      deviations (RSDs) ranging from 1.1% to 5.4%. The limit of detection (LOD) for the 
      enantiomers in tobacco and soil varied from 0.005 to 0.007 mg/kg, and the limit 
      of quantitation (LOQ) ranged from 0.017 to 0.020 mg/kg. In this method, only a 
      small amount of methanol was consumed to obtain a rapid stereoselective 
      separation. This proposed method showed good accuracy and precision and might be 
      suitable for fast enantioselective determination of metalaxyl in food and 
      environmental samples. The developed method was further validated by application 
      to the analysis of authentic samples.
CI  - (c) 2020 Wiley Periodicals, Inc.
FAU - Yang, Fei
AU  - Yang F
AUID- ORCID: 0000-0002-9179-375X
AD  - China National Tobacco Quality Supervision and Test Center, Zhengzhou, China.
FAU - Wang, Ying
AU  - Wang Y
AD  - China National Tobacco Quality Supervision and Test Center, Zhengzhou, China.
FAU - Liu, Shanshan
AU  - Liu S
AD  - China National Tobacco Quality Supervision and Test Center, Zhengzhou, China.
FAU - He, Chen
AU  - He C
AD  - Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou, China.
FAU - Tao, Xiaoqiu
AU  - Tao X
AD  - Sichuan Tobacco Quality Supervision and Testing Station, Chengdu, China.
FAU - Deng, Huimin
AU  - Deng H
AD  - China National Tobacco Quality Supervision and Test Center, Zhengzhou, China.
FAU - Tang, Gangling
AU  - Tang G
AD  - China National Tobacco Quality Supervision and Test Center, Zhengzhou, China.
FAU - Bian, Zhaoyang
AU  - Bian Z
AD  - China National Tobacco Quality Supervision and Test Center, Zhengzhou, China.
FAU - Fan, Ziyan
AU  - Fan Z
AD  - China National Tobacco Quality Supervision and Test Center, Zhengzhou, China.
LA  - eng
PT  - Journal Article
DEP - 20200221
PL  - United States
TA  - Chirality
JT  - Chirality
JID - 8914261
SB  - IM
OTO - NOTNLM
OT  - enantioseparation
OT  - fungicide
OT  - soil
OT  - supercritical fluid chromatography-tandem mass spectrometry (SFC-MS/MS)
OT  - tobacco
EDAT- 2020/02/23 06:00
MHDA- 2020/02/23 06:01
CRDT- 2020/02/22 06:00
PHST- 2019/12/13 00:00 [received]
PHST- 2020/01/19 00:00 [revised]
PHST- 2020/01/20 00:00 [accepted]
PHST- 2020/02/23 06:00 [pubmed]
PHST- 2020/02/23 06:01 [medline]
PHST- 2020/02/22 06:00 [entrez]
AID - 10.1002/chir.23184 [doi]
PST - ppublish
SO  - Chirality. 2020 May;32(5):505-514. doi: 10.1002/chir.23184. Epub 2020 Feb 21.