PMID- 32085411
OWN - NLM
STAT- MEDLINE
DCOM- 20201130
LR  - 20231113
IS  - 1420-3049 (Electronic)
IS  - 1420-3049 (Linking)
VI  - 25
IP  - 4
DP  - 2020 Feb 18
TI  - NH(2)-MIL-53(Al) Polymer Monolithic Column for In-Tube Solid-Phase 
      Microextraction Combined with UHPLC-MS/MS for Detection of Trace Sulfonamides in 
      Food Samples.
LID - 10.3390/molecules25040897 [doi]
LID - 897
AB  - In this study, a novel monolithic capillary column based on a NH(2)-MIL-53(Al) 
      metal-organic framework (MOF) incorporated in poly (3-acrylamidophenylboronic 
      acid/methacrylic acid-co-ethylene glycol dimethacrylate) (poly 
      (AAPBA/MAA-co-EGDMA)) was prepared using an in situ polymerization method. The 
      characteristics of the MOF-polymer monolithic column were investigated by 
      scanning electron microscopy, Fourier-transform infrared spectroscopy, X-ray 
      photoelectron spectroscopy, X-ray diffractometry, Brunauer-Emmett-Teller 
      analysis, and thermogravimetric analysis. The prepared MOF-polymer monolithic 
      column showed good permeability, high extraction efficiency, chemical stability, 
      and good reproducibility. The MOF-polymer monolithic column was used for in-tube 
      solid-phase microextraction (SPME) to efficiently adsorb trace sulfonamides from 
      food samples. A novel method combining MOF-polymer-monolithic-column-based SPME 
      with ultra-high performance liquid chromatography-tandem mass spectrometry 
      (UHPLC-MS/MS) was successfully developed. The linear range was from 0.015 to 25.0 
      microg/L, with low limits of detection of 1.3-4.7 ng/L and relative standard 
      deviations (RSDs) of < 6.1%. Eight trace sulfonamides in fish and chicken samples 
      were determined, with recoveries of the eight analytes ranging from 85.7% to 113% 
      and acceptable RSDs of < 7.3%. These results demonstrate that the novel 
      MOF-polymer-monolithic-column-based SPME coupled with UHPLC-MS/MS is a highly 
      sensitive, practical, and convenient method for monitoring trace sulfonamides in 
      food samples previously extracted with an adequate solvent.
FAU - Zhang, Qian-Chun
AU  - Zhang QC
AD  - School of Biology and Chemistry, Key Laboratory of Chemical Synthesis and 
      Environmental Pollution Control-Remediation Technology of Guizhou Province, 
      Xingyi Normal University for Nationalities, Xingyi 562400, China.
FAU - Xia, Guang-Ping
AU  - Xia GP
AD  - School of Biology and Chemistry, Key Laboratory of Chemical Synthesis and 
      Environmental Pollution Control-Remediation Technology of Guizhou Province, 
      Xingyi Normal University for Nationalities, Xingyi 562400, China.
FAU - Liang, Jun-Yi
AU  - Liang JY
AD  - School of Biology and Chemistry, Key Laboratory of Chemical Synthesis and 
      Environmental Pollution Control-Remediation Technology of Guizhou Province, 
      Xingyi Normal University for Nationalities, Xingyi 562400, China.
FAU - Zhang, Xiao-Lan
AU  - Zhang XL
AD  - School of Biology and Chemistry, Key Laboratory of Chemical Synthesis and 
      Environmental Pollution Control-Remediation Technology of Guizhou Province, 
      Xingyi Normal University for Nationalities, Xingyi 562400, China.
FAU - Jiang, Li
AU  - Jiang L
AD  - School of Biology and Chemistry, Key Laboratory of Chemical Synthesis and 
      Environmental Pollution Control-Remediation Technology of Guizhou Province, 
      Xingyi Normal University for Nationalities, Xingyi 562400, China.
FAU - Zheng, Yu-Guo
AU  - Zheng YG
AD  - School of Biology and Chemistry, Key Laboratory of Chemical Synthesis and 
      Environmental Pollution Control-Remediation Technology of Guizhou Province, 
      Xingyi Normal University for Nationalities, Xingyi 562400, China.
FAU - Wang, Xing-Yi
AU  - Wang XY
AD  - School of Biology and Chemistry, Key Laboratory of Chemical Synthesis and 
      Environmental Pollution Control-Remediation Technology of Guizhou Province, 
      Xingyi Normal University for Nationalities, Xingyi 562400, China.
LA  - eng
GR  - KY2018078/Technological Talents in Universities of Guizhou Province/
GR  - 21505115/National Natural Science Foundation of China/
GR  - 2017014/Higher Education Improvement Project of Guizhou Province/
GR  - LH20177026/Science and Technology Foundation of the Guizhou Provincial Science 
      and Technology Department/
PT  - Journal Article
DEP - 20200218
PL  - Switzerland
TA  - Molecules
JT  - Molecules (Basel, Switzerland)
JID - 100964009
RN  - 0 (Metal-Organic Frameworks)
RN  - 0 (Polymers)
RN  - 0 (Sulfonamides)
SB  - IM
MH  - Adsorption
MH  - Animals
MH  - Calibration
MH  - Chickens
MH  - Chromatography, High Pressure Liquid
MH  - Fishes
MH  - *Food Analysis
MH  - Hydrogen-Ion Concentration
MH  - Metal-Organic Frameworks
MH  - Polymers/*chemistry
MH  - Rheology
MH  - *Solid Phase Microextraction
MH  - Spectroscopy, Fourier Transform Infrared
MH  - Sulfonamides/*analysis
MH  - *Tandem Mass Spectrometry
MH  - Temperature
MH  - X-Ray Diffraction
PMC - PMC7070345
OTO - NOTNLM
OT  - metal-organic framework
OT  - monolithic capillary column
OT  - solid-phase microextraction
OT  - sulfonamides
OT  - ultra-high performance liquid chromatography-tandem mass spectrometry
COIS- The authors declare no conflict of interest.
EDAT- 2020/02/23 06:00
MHDA- 2020/12/01 06:00
PMCR- 2020/02/18
CRDT- 2020/02/23 06:00
PHST- 2020/01/20 00:00 [received]
PHST- 2020/02/14 00:00 [revised]
PHST- 2020/02/15 00:00 [accepted]
PHST- 2020/02/23 06:00 [entrez]
PHST- 2020/02/23 06:00 [pubmed]
PHST- 2020/12/01 06:00 [medline]
PHST- 2020/02/18 00:00 [pmc-release]
AID - molecules25040897 [pii]
AID - molecules-25-00897 [pii]
AID - 10.3390/molecules25040897 [doi]
PST - epublish
SO  - Molecules. 2020 Feb 18;25(4):897. doi: 10.3390/molecules25040897.