PMID- 32089102
OWN - NLM
STAT- MEDLINE
DCOM- 20200903
LR  - 20200903
IS  - 2578-5826 (Electronic)
IS  - 2578-5826 (Linking)
VI  - 43
IP  - 2
DP  - 2020 Jun
TI  - Dry eye in rheumatoid arthritis: relation to disease activity.
PG  - 92-97
LID - 10.1080/25785826.2020.1729597 [doi]
AB  - The aim of this study was to find the correlation between severity of dry eye and 
      rheumatoid arthritis (RA) disease activity. Forty- two RA patients with dry eye 
      were recruited from Rheumatology Outpatient Clinic in Minia University Hospital. 
      Assessment of RA disease activity was performed using disease activity score 
      (DAS-28). Ocular tests include Schirmer test I, tear film break up time (TBUT) 
      and ocular staining score (OSS) was performed by ophthalmologist to find evidence 
      of ocular dryness. Erythrocyte sedimentation rate (ESR), rheumatoid factor (RF), 
      anti SSA/Ro and anti SSB/La was also tested. Patients with severe dry (OSS >/= 3) 
      underwent minor salivary gland biopsy (MSGB) as suspected to have secondary 
      Sjogren's syndrome (SS). Of 42 RA patients, 30 had definite dry eye. DAS-28 did 
      not show significant correlation with any of ocular tests for dryness while the 
      duration of RA was significantly positively correlated with Schirmer test and 
      OSS. The biopsy results of RA patients with severe dry eye show no evidence of 
      SS. The severity of dry eye is not correlated with activity of RA but with its 
      duration.
FAU - Abd-Allah, Nashwa M
AU  - Abd-Allah NM
AUID- ORCID: 0000-0001-6127-0440
AD  - Department of Rheumatology and Rehabilitation, Faculty of Medicine, Minia 
      University, Minia, Egypt.
FAU - Hassan, Amal Aly
AU  - Hassan AA
AD  - Department of Rheumatology and Rehabilitation, Faculty of Medicine, Minia 
      University, Minia, Egypt.
FAU - Omar, Gihan
AU  - Omar G
AD  - Department of Rheumatology and Rehabilitation, Faculty of Medicine, Minia 
      University, Minia, Egypt.
FAU - Hamdy, Mona
AU  - Hamdy M
AD  - Department of Rheumatology and Rehabilitation, Faculty of Medicine, Minia 
      University, Minia, Egypt.
FAU - Abdelaziz, Sahar Torky A
AU  - Abdelaziz STA
AD  - Department of Ophthalmology, Faculty of Medicine, Minia University, Minia, Egypt.
FAU - Abd El Hamid, Waleed Mahmoud
AU  - Abd El Hamid WM
AD  - Department of Clinical Pathology, Faculty of Medicine, Minia University, Minia, 
      Egypt.
FAU - Moussa, Rabab A
AU  - Moussa RA
AD  - Department of Pathology, Faculty of Medicine, Minia University, Minia, Egypt.
LA  - eng
PT  - Journal Article
DEP - 20200223
PL  - England
TA  - Immunol Med
JT  - Immunological medicine
JID - 101736847
SB  - IM
MH  - Adult
MH  - Dry Eye Syndromes/diagnosis/*etiology
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Rheumatic Fever/*complications/diagnosis
MH  - Severity of Illness Index
MH  - Time Factors
OTO - NOTNLM
OT  - Rheumatoid arthritis
OT  - disease activity score 28 (DAS-28)
OT  - dry eye
OT  - ocular tests
OT  - secondary Sjogren's syndrome (SS)
EDAT- 2020/02/25 06:00
MHDA- 2020/09/04 06:00
CRDT- 2020/02/25 06:00
PHST- 2020/02/25 06:00 [pubmed]
PHST- 2020/09/04 06:00 [medline]
PHST- 2020/02/25 06:00 [entrez]
AID - 10.1080/25785826.2020.1729597 [doi]
PST - ppublish
SO  - Immunol Med. 2020 Jun;43(2):92-97. doi: 10.1080/25785826.2020.1729597. Epub 2020 
      Feb 23.