PMID- 32090238
OWN - NLM
STAT- MEDLINE
DCOM- 20210115
LR  - 20210115
IS  - 1464-3502 (Electronic)
IS  - 0735-0414 (Linking)
VI  - 55
IP  - 3
DP  - 2020 Apr 16
TI  - Alcohol Consumption by Beverage Type and Risk of Breast Cancer: A Dose-Response 
      Meta-Analysis of Prospective Cohort Studies.
PG  - 246-253
LID - 10.1093/alcalc/agaa012 [doi]
AB  - AIMS: Alcohol intake has been shown to increase the risk of breast cancer. 
      However, the dose-response analysis of different alcoholic beverages (spirits, 
      wine and beer) is not clear. Our meta-analysis aims to provide a dose-response 
      estimation between different alcohols and breast cancer risk. METHODS: Search of 
      PubMed and Web of Science and manual searches were conducted up to 1 December 
      2018, and summary relative risks (RRs) and attributable risk percentage (ARP) for 
      alcohol intake on the development of breast cancer were calculated. Dose-response 
      meta-analysis modeled relationships between drinking type and breast cancer risk. 
      Sources of heterogeneity were explored, and sensitivity analyses were conducted 
      to test the robustness of findings. RESULTS: In total, 22 cohort studies and 
      45,350 breast cancer cases were included. Current drinkers for ER+ had an 
      increased risk compared with never drinkers. In dose-response analysis, there was 
      a statistically significant linear trend with breast cancer risk increasing 
      gradually by total alcohol and wine dose: when adding 10 g per day, the risk 
      increased by 10.5% (RR = 1.10, 95%CI = 1.08-1.13) in total alcohol and 8.9% 
      (RR = 1.08, 95%CI = 1.04-1.14) in wine. For postmenopausal women, the risk 
      increases by 11.1% (RR = 1.11, 95%CI = 1.09-1.13) with every 10 g of total 
      alcohol increase. Furthermore, the breast cancer alcohol-attributed percentage is 
      higher in Europe than in North America and Asia. CONCLUSIONS: The effect of 
      drinking on the incidence of breast cancer is mainly manifested in ER+ breast 
      cancer. Quantitative analysis showed total drinking had a significant risk for 
      breast cancer, especially for postmenopausal women. However, for different 
      alcohols, just wine intake has the similar results.
CI  - (c) The Author(s) 2020. Medical Council on Alcohol and Oxford University Press. All 
      rights reserved.
FAU - Sun, Qiuyu
AU  - Sun Q
AD  - Department of Epidemiology and Statistics, College of Public Health, Zhengzhou 
      University, 100 Science Avenue, Zhengzhou 450001, Henan, China.
AD  - Henan Key Laboratory of Tumor Epidemiology, Zhengzhou University, 40 Daxue Road, 
      Zhengzhou 450052, China.
FAU - Xie, Weihong
AU  - Xie W
AD  - Department of Oral and Maxillofacial Surgery, the First Affiliated Hospital, 
      Zhengzhou University, Zhengzhou 450052, Henan, China.
FAU - Wang, Yanli
AU  - Wang Y
AD  - Department of Epidemiology and Statistics, College of Public Health, Zhengzhou 
      University, 100 Science Avenue, Zhengzhou 450001, Henan, China.
AD  - Henan Key Laboratory of Tumor Epidemiology, Zhengzhou University, 40 Daxue Road, 
      Zhengzhou 450052, China.
FAU - Chong, Feifei
AU  - Chong F
AD  - Department of Epidemiology and Statistics, College of Public Health, Zhengzhou 
      University, 100 Science Avenue, Zhengzhou 450001, Henan, China.
AD  - Henan Key Laboratory of Tumor Epidemiology, Zhengzhou University, 40 Daxue Road, 
      Zhengzhou 450052, China.
FAU - Song, Mengmeng
AU  - Song M
AD  - Department of Epidemiology and Statistics, College of Public Health, Zhengzhou 
      University, 100 Science Avenue, Zhengzhou 450001, Henan, China.
AD  - Henan Key Laboratory of Tumor Epidemiology, Zhengzhou University, 40 Daxue Road, 
      Zhengzhou 450052, China.
FAU - Li, Tiandong
AU  - Li T
AD  - Department of Epidemiology and Statistics, College of Public Health, Zhengzhou 
      University, 100 Science Avenue, Zhengzhou 450001, Henan, China.
AD  - Henan Key Laboratory of Tumor Epidemiology, Zhengzhou University, 40 Daxue Road, 
      Zhengzhou 450052, China.
FAU - Xu, Linping
AU  - Xu L
AD  - Department of Teaching and Research, Henan Tumor Hospital, No. 127, Dongming 
      Road, Zhengzhou 450003, Henan, China.
FAU - Song, Chunhua
AU  - Song C
AD  - Department of Epidemiology and Statistics, College of Public Health, Zhengzhou 
      University, 100 Science Avenue, Zhengzhou 450001, Henan, China.
AD  - Henan Key Laboratory of Tumor Epidemiology, Zhengzhou University, 40 Daxue Road, 
      Zhengzhou 450052, China.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Systematic Review
PL  - England
TA  - Alcohol Alcohol
JT  - Alcohol and alcoholism (Oxford, Oxfordshire)
JID - 8310684
SB  - IM
MH  - Alcohol Drinking/*adverse effects
MH  - Alcoholic Beverages/*adverse effects
MH  - Beer/adverse effects
MH  - Breast Neoplasms/chemically induced/*etiology
MH  - Dose-Response Relationship, Drug
MH  - Female
MH  - Humans
MH  - Prospective Studies
MH  - Risk Factors
MH  - Wine/adverse effects
EDAT- 2020/02/25 06:00
MHDA- 2021/01/16 06:00
CRDT- 2020/02/25 06:00
PHST- 2019/11/29 00:00 [received]
PHST- 2020/01/09 00:00 [revised]
PHST- 2020/01/27 00:00 [accepted]
PHST- 2020/02/25 06:00 [pubmed]
PHST- 2021/01/16 06:00 [medline]
PHST- 2020/02/25 06:00 [entrez]
AID - 5748223 [pii]
AID - 10.1093/alcalc/agaa012 [doi]
PST - ppublish
SO  - Alcohol Alcohol. 2020 Apr 16;55(3):246-253. doi: 10.1093/alcalc/agaa012.