PMID- 32092169 OWN - NLM STAT- MEDLINE DCOM- 20210128 LR - 20210128 IS - 1600-051X (Electronic) IS - 0303-6979 (Linking) VI - 47 IP - 5 DP - 2020 May TI - Volume stability of the augmented sinus using a collagenated bovine bone mineral grafted in case of a perforated Schneiderian membrane: An experimental study in rabbits. PG - 649-656 LID - 10.1111/jcpe.13273 [doi] AB - OBJECTIVES: To determine the volume stability of a sinus augmented with a collagenated bovine bone mineral (CBBM) in case of an intact or perforated Schneiderian membrane (SM). MATERIALS AND METHODS: A bilateral sinus augmentation procedure was performed in eight rabbits. The SM was intentionally perforated in one side (SMP group), while it remained intact in contra-lateral side (control group) and the same amount of CBBM was then grafted. At 12 weeks, the animals were euthanized for radiographic and histomorphometric analyses. RESULTS: The augmented volume did not differ significantly between the two groups: 262.2 +/- 32.1 mm(3) in SMP group and 261.9 +/- 48.5 mm(3) in the control group (p = .959). There was no significant difference in the total augmented area: 24.7 +/- 5.2 mm(2) in SMP group and 23.2 +/- 2.9 mm(2) in the control group (p = .773). The areas of newly formed bone also did not differ significantly between the two groups, but was significantly lower at the centre of the augmented region than in the region of the surgical window in both groups (p < .05). CONCLUSION: A perforation of the SM in a rabbit model does neither impact the augmented volume nor new bone formation following grafting of the sinus with a CBBM. CI - (c) 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. FAU - Paik, Jeong-Won AU - Paik JW AD - Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry, Seoul, Korea. FAU - Cha, Jae-Kook AU - Cha JK AD - Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry, Seoul, Korea. FAU - Paeng, Kyeong-Won AU - Paeng KW AD - Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry, Seoul, Korea. FAU - Kim, Myong-Ji AU - Kim MJ AD - Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry, Seoul, Korea. FAU - Thoma, Daniel S AU - Thoma DS AUID- ORCID: 0000-0002-1764-7447 AD - Clinic of Reconstructive Dentistry, Center of Dental Medicine, University of Zurich, Zurich, Switzerland. FAU - Jung, Ronald E AU - Jung RE AD - Clinic of Reconstructive Dentistry, Center of Dental Medicine, University of Zurich, Zurich, Switzerland. FAU - Jung, Ui-Won AU - Jung UW AUID- ORCID: 0000-0001-6371-4172 AD - Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry, Seoul, Korea. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20200311 PL - United States TA - J Clin Periodontol JT - Journal of clinical periodontology JID - 0425123 RN - 0 (Bone Substitutes) RN - 0 (Minerals) SB - IM MH - Animals MH - *Bone Substitutes/therapeutic use MH - Bone Transplantation MH - Cattle MH - Maxillary Sinus/diagnostic imaging/surgery MH - Minerals/therapeutic use MH - Nasal Mucosa/surgery MH - Osteogenesis MH - Rabbits MH - *Sinus Floor Augmentation OTO - NOTNLM OT - Schneiderian membrane OT - animal study OT - volume stability OT - xenograft EDAT- 2020/02/25 06:00 MHDA- 2021/01/29 06:00 CRDT- 2020/02/25 06:00 PHST- 2019/08/01 00:00 [received] PHST- 2019/12/16 00:00 [revised] PHST- 2020/02/21 00:00 [accepted] PHST- 2020/02/25 06:00 [pubmed] PHST- 2021/01/29 06:00 [medline] PHST- 2020/02/25 06:00 [entrez] AID - 10.1111/jcpe.13273 [doi] PST - ppublish SO - J Clin Periodontol. 2020 May;47(5):649-656. doi: 10.1111/jcpe.13273. Epub 2020 Mar 11.