PMID- 32095190 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20240328 IS - 1923-2829 (Print) IS - 1923-2837 (Electronic) IS - 1923-2829 (Linking) VI - 11 IP - 1 DP - 2020 Feb TI - Indications of Cardiac Resynchronization in Non-Left Bundle Branch Block: Clinical Review of Available Evidence. PG - 1-8 LID - 10.14740/cr989 [doi] AB - Cardiac resynchronization therapy (CRT) benefits have been firmly established in patients with heart failure and reduced left ventricular ejection fraction (HFrEF), who remain in New York Heart Association (NYHA) functional classes II and III, despite optimal medical therapy, and have a wide QRS complex. An important and consistent finding in published systematic reviews and in subgroup analyses is that the benefits of CRT are maximum for patients with a broader QRS durations, typically described as QRS duration > 150 ms, and for patients with a typical left bundle branch block (LBBB) QRS morphology. It remains uncertain whether patients with non-LBBB QRS complex morphology clearly benefit from CRT or only modestly respond. CI - Copyright 2020, Henin et al. FAU - Henin, Maged AU - Henin M AD - University Hospital Waterford, Waterford, Ireland. FAU - Ragy, Hany AU - Ragy H AD - National Heart Institute, Cairo, Egypt. FAU - Mannion, James AU - Mannion J AD - University Hospital Waterford, Waterford, Ireland. FAU - David, Santhosh AU - David S AD - Cardiology Department, Letterkenny University Hospital, Donegal, Ireland. FAU - Refila, Beshoy AU - Refila B AD - Cardiology Department, Heart and Vascular Center, Mater Private Hospital, Dublin 7, Ireland. FAU - Boles, Usama AU - Boles U AD - Cardiology Department, Heart and Vascular Center, Mater Private Hospital, Dublin 7, Ireland. LA - eng PT - Journal Article PT - Review DEP - 20200126 PL - Canada TA - Cardiol Res JT - Cardiology research JID - 101557543 PMC - PMC7011924 OTO - NOTNLM OT - HFrEF: Cardiac resynchronization therapy OT - Non-LBBB OT - QRS duration OT - RBBB OT - Typical LBBB COIS- None to declare. EDAT- 2020/02/26 06:00 MHDA- 2020/02/26 06:01 PMCR- 2020/02/01 CRDT- 2020/02/26 06:00 PHST- 2019/11/19 00:00 [received] PHST- 2019/12/16 00:00 [accepted] PHST- 2020/02/26 06:00 [entrez] PHST- 2020/02/26 06:00 [pubmed] PHST- 2020/02/26 06:01 [medline] PHST- 2020/02/01 00:00 [pmc-release] AID - 10.14740/cr989 [doi] PST - ppublish SO - Cardiol Res. 2020 Feb;11(1):1-8. doi: 10.14740/cr989. Epub 2020 Jan 26.