PMID- 32098423 OWN - NLM STAT- MEDLINE DCOM- 20201005 LR - 20231113 IS - 1660-4601 (Electronic) IS - 1661-7827 (Print) IS - 1660-4601 (Linking) VI - 17 IP - 4 DP - 2020 Feb 22 TI - Hybrid Methodology to Improve Health Status Utility Values Derivation Using EQ-5D-5L and Advanced Multi-Criteria Techniques. LID - 10.3390/ijerph17041423 [doi] LID - 1423 AB - This paper presented a new approach to the calculation of quality-adjusted life years (QALY) based on multi-criteria decision-making (MCDM) methods and using the EQ-5D-5L questionnaire. The health status utility values were calculated through a hybrid methodology. We combined the analytic hierarchy process (AHP), the AHP with a D-number extended fuzzy preference relation (D-AHP), the fuzzy analytic hierarchy process (F-AHP), and the technique for order preference by similarity to the ideal solution (TOPSIS) to obtain individual and aggregated utility values. The preference data were elicited using a sample of individuals from a Colombian university. In all tested methods, the ordinal preferences were consistent, and the weights were compared using the Euclidean distance criterion (EDC). We identified F-AHP-TOPSIS as the optimal method; its benefits were associated with modeling the response options of the EQ-5D in linguistic terms, it gave the best approximation to the initial preferences according to EDC, and it could be used as an alternative to the known prioritization method. This hybrid methodology was particularly useful in certain medical decisions concerned with understanding how a specific person values his or her current health or possible health outcomes from different interventions in small population samples and studies carried out in low- and middle-low-income countries. FAU - Vasquez, Johanna AU - Vasquez J AD - Departamento de Economia, Facultad de Ciencias Humanas y Economicas, Universidad Nacional de Colombia Sede Medellin, Medellin 050034, Colombia. FAU - Botero, Sergio AU - Botero S AD - Departamento de Ingenieria de la Organizacion, Facultad de Minas, Universidad Nacional de Colombia Sede Medellin, Medellin 050034, Colombia. LA - eng PT - Journal Article DEP - 20200222 PL - Switzerland TA - Int J Environ Res Public Health JT - International journal of environmental research and public health JID - 101238455 SB - IM MH - *Decision Making, Computer-Assisted MH - Female MH - *Health Status MH - Humans MH - Male MH - *Models, Theoretical MH - Quality of Life MH - *Quality-Adjusted Life Years MH - Surveys and Questionnaires PMC - PMC7068428 OTO - NOTNLM OT - AHP OT - MCDM OT - TOPSIS OT - elicit preferences OT - health utility values COIS- The authors certify that they have no affiliations with or involvement in any organization or entity with any financial or non-financial interest in the subject matter or materials discussed in this manuscript. EDAT- 2020/02/27 06:00 MHDA- 2020/10/06 06:00 PMCR- 2020/02/01 CRDT- 2020/02/27 06:00 PHST- 2020/01/18 00:00 [received] PHST- 2020/02/19 00:00 [revised] PHST- 2020/02/20 00:00 [accepted] PHST- 2020/02/27 06:00 [entrez] PHST- 2020/02/27 06:00 [pubmed] PHST- 2020/10/06 06:00 [medline] PHST- 2020/02/01 00:00 [pmc-release] AID - ijerph17041423 [pii] AID - ijerph-17-01423 [pii] AID - 10.3390/ijerph17041423 [doi] PST - epublish SO - Int J Environ Res Public Health. 2020 Feb 22;17(4):1423. doi: 10.3390/ijerph17041423.