PMID- 32104025
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220413
IS  - 1178-7007 (Print)
IS  - 1178-7007 (Electronic)
IS  - 1178-7007 (Linking)
VI  - 13
DP  - 2020
TI  - Association Between Cognitive Impairment and Blood Pressure Among Patients with 
      Type II Diabetes Mellitus in Southern Iran.
PG  - 289-296
LID - 10.2147/DMSO.S238247 [doi]
AB  - PURPOSE: Both type 2 diabetes mellitus (T2DM) and hypertension are regarded as 
      life-threatening diseases known to be risk factors for vascular diseases. They 
      may be associated with the increased risk of cognitive impairment (CI), although 
      there are conflicting data relating hypertension to the risk of CI. Therefore, 
      this study aimed to explore the probable association between hypertension and CI 
      in patients with T2DM. PATIENTS AND METHODS: This cross-sectional study assessed 
      the degree of CI of a total of 350 patients with T2DM using the Mini-Mental State 
      Examination (MMSE). In clinical examinations, the mean of the first, second, and 
      third measurements of systolic and diastolic blood pressure (SBP and DBP) was 
      recorded. RESULTS: The mean of subjects' MMSE scores was 25.48 +/- 3.73. 
      Additionally, the means of SBPSs and DBPs were found to be 118.50 +/- 17.27 and 
      73.47 +/- 10.25 mmHg, respectively. The Spearman correlation coefficient showed a 
      mild, significant, negative correlation between MMSE scores and those of SBP (r = 
      -0.199, p <0.001) and DBP (r = -0.233, p <0.001). Accordingly, a 1-unit increase 
      in one's SBP would lead to a significant rise in mild CI (2.8%) in comparison 
      with subjects who have normal CIs. However, it was shown that if one's DBP 
      increased by 1 unit, the odds of mild CI occurring would increase significantly 
      by 6.7% compared with those who have normal CIs. CONCLUSION: The present findings 
      revealed that hypertension might be related to the development of CI in people 
      with a diabetic condition, thus emphasizing the fact that the prevention and 
      treatment of these highly prevalent diseases assume the utmost significance.
CI  - (c) 2020 Jamalnia et al.
FAU - Jamalnia, Sheida
AU  - Jamalnia S
AD  - Medical Journalism Department, Shiraz University of Medical Sciences, Shiraz, 
      Iran.
FAU - Javanmardifard, Sorur
AU  - Javanmardifard S
AD  - School of Nursing and Midwifery, Ahvaz Jundishapur University of Medical 
      Sciences, Ahvaz, Iran.
FAU - Akbari, Hamed
AU  - Akbari H
AUID- ORCID: 0000-0002-9939-6652
AD  - Endocrinology and Metabolism Research Center, Institute of Basic and Clinical 
      Physiology Sciences, Kerman University of Medical Sciences, Kerman, Iran.
AD  - Department of Biochemistry, Afzalipur Faculty of Medicine, Kerman University of 
      Medical Sciences, Kerman, Iran.
FAU - Sadeghi, Erfan
AU  - Sadeghi E
AD  - Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, 
      Fasa, Iran.
AD  - Department of Biostatistics and Epidemiology, Faculty of Health, Isfahan 
      University of Medical Sciences, Isfahan, Iran.
FAU - Bijani, Mostafa
AU  - Bijani M
AD  - Department of Medical Surgical Nursing, Fasa University of Medical Sciences, 
      Fasa, Iran.
LA  - eng
PT  - Journal Article
DEP - 20200205
PL  - New Zealand
TA  - Diabetes Metab Syndr Obes
JT  - Diabetes, metabolic syndrome and obesity : targets and therapy
JID - 101515585
PMC - PMC7008183
OTO - NOTNLM
OT  - blood pressure
OT  - cognitive impairment
OT  - hypertension
OT  - type II diabetes mellitus
COIS- The author reports no conflicts of interest in this work.
EDAT- 2020/02/28 06:00
MHDA- 2020/02/28 06:01
PMCR- 2020/02/05
CRDT- 2020/02/28 06:00
PHST- 2019/11/12 00:00 [received]
PHST- 2020/01/15 00:00 [accepted]
PHST- 2020/02/28 06:00 [entrez]
PHST- 2020/02/28 06:00 [pubmed]
PHST- 2020/02/28 06:01 [medline]
PHST- 2020/02/05 00:00 [pmc-release]
AID - 238247 [pii]
AID - 10.2147/DMSO.S238247 [doi]
PST - epublish
SO  - Diabetes Metab Syndr Obes. 2020 Feb 5;13:289-296. doi: 10.2147/DMSO.S238247. 
      eCollection 2020.