PMID- 32104027
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231113
IS  - 1178-7007 (Print)
IS  - 1178-7007 (Electronic)
IS  - 1178-7007 (Linking)
VI  - 13
DP  - 2020
TI  - Khat Chewing and Type 2 Diabetes Mellitus.
PG  - 307-312
LID - 10.2147/DMSO.S240680 [doi]
AB  - OBJECTIVE: Knowledge about the effects of khat chewing on type 2 diabetes 
      mellitus (T2DM) development and glycemic control is very sparse. Emerging data 
      suggest that khat chewing may increase the risk of T2DM occurrence. Therefore, 
      this study aimed to measure the prevalence of khat chewing in Saudi people with 
      T2DM in Jazan, Saudi Arabia and to determine the association of khat chewing with 
      T2DM development and glycemic control in T2DM. METHODS: This is an analytical, 
      cross-sectional study that included 472 Saudi participants selected randomly from 
      primary healthcare centers in Jazan, Saudi Arabia. A chi-square test and logistic 
      regression were performed in the statistical analysis. RESULTS: The prevalence of 
      khat chewing in Saudi patients with T2DM in Jazan was 29.3%. After adjusting for 
      covariates, khat chewing was significantly associated with T2DM (odds ratio 3.5), 
      indicating that khat chewers had a more than three times higher risk of 
      developing T2DM than those who do not chew khat. However, there was no 
      association between khat chewing and glycemic control in T2DM. CONCLUSION: Khat 
      chewing was highly prevalent in Saudi people with T2DM in Jazan, Saudi Arabia. 
      There was an association between khat chewing and the development of T2DM. 
      Establishing the causal association of khat chewing with T2DM development and 
      glycemic control and clarifying the biological role of khat in T2DM are important 
      aims for future studies.
CI  - (c) 2020 Badedi et al.
FAU - Badedi, Mohammed
AU  - Badedi M
AUID- ORCID: 0000-0002-2063-2094
AD  - Jazan Diabetes and Endocrine Center, Ministry of Health, Jazan, Saudi Arabia.
FAU - Darraj, Hussain
AU  - Darraj H
AUID- ORCID: 0000-0001-9694-007X
AD  - Jazan Diabetes and Endocrine Center, Ministry of Health, Jazan, Saudi Arabia.
FAU - Hummadi, Abdulrahman
AU  - Hummadi A
AD  - Jazan Diabetes and Endocrine Center, Ministry of Health, Jazan, Saudi Arabia.
FAU - Najmi, Abdullah
AU  - Najmi A
AD  - Jazan Health Affairs, Ministry of Health, Jazan, Saudi Arabia.
FAU - Solan, Yahiya
AU  - Solan Y
AD  - Jazan Diabetes and Endocrine Center, Ministry of Health, Jazan, Saudi Arabia.
FAU - Zakry, Ibrahim
AU  - Zakry I
AD  - Jazan Diabetes and Endocrine Center, Ministry of Health, Jazan, Saudi Arabia.
FAU - Khawaji, Abdullah
AU  - Khawaji A
AD  - Jazan Diabetes and Endocrine Center, Ministry of Health, Jazan, Saudi Arabia.
FAU - Zaylai, Sayedah
AU  - Zaylai S
AD  - Jazan Diabetes and Endocrine Center, Ministry of Health, Jazan, Saudi Arabia.
FAU - Rajeh, Norah
AU  - Rajeh N
AD  - Jazan Diabetes and Endocrine Center, Ministry of Health, Jazan, Saudi Arabia.
FAU - Alhafaf, Hassan
AU  - Alhafaf H
AD  - Jazan Diabetes and Endocrine Center, Ministry of Health, Jazan, Saudi Arabia.
FAU - Hakami, Wali
AU  - Hakami W
AD  - Jazan Diabetes and Endocrine Center, Ministry of Health, Jazan, Saudi Arabia.
FAU - Bakkari, Awaji
AU  - Bakkari A
AD  - Jazan Diabetes and Endocrine Center, Ministry of Health, Jazan, Saudi Arabia.
FAU - Kriry, Maryam
AU  - Kriry M
AD  - Jazan Diabetes and Endocrine Center, Ministry of Health, Jazan, Saudi Arabia.
FAU - Dagreri, Abdulraheem
AU  - Dagreri A
AD  - Jazan Diabetes and Endocrine Center, Ministry of Health, Jazan, Saudi Arabia.
FAU - Haddad, Ebrahim
AU  - Haddad E
AD  - Jazan Diabetes and Endocrine Center, Ministry of Health, Jazan, Saudi Arabia.
LA  - eng
PT  - Journal Article
DEP - 20200210
PL  - New Zealand
TA  - Diabetes Metab Syndr Obes
JT  - Diabetes, metabolic syndrome and obesity : targets and therapy
JID - 101515585
PMC - PMC7024885
OTO - NOTNLM
OT  - catha edulis
OT  - khat chewing
OT  - type 2 diabetes mellitus
COIS- The authors report no conflict of interests in this work.
EDAT- 2020/02/28 06:00
MHDA- 2020/02/28 06:01
PMCR- 2020/02/10
CRDT- 2020/02/28 06:00
PHST- 2019/12/01 00:00 [received]
PHST- 2020/01/17 00:00 [accepted]
PHST- 2020/02/28 06:00 [entrez]
PHST- 2020/02/28 06:00 [pubmed]
PHST- 2020/02/28 06:01 [medline]
PHST- 2020/02/10 00:00 [pmc-release]
AID - 240680 [pii]
AID - 10.2147/DMSO.S240680 [doi]
PST - epublish
SO  - Diabetes Metab Syndr Obes. 2020 Feb 10;13:307-312. doi: 10.2147/DMSO.S240680. 
      eCollection 2020.