PMID- 32105653
OWN - NLM
STAT- MEDLINE
DCOM- 20201106
LR  - 20221207
IS  - 1773-0619 (Electronic)
IS  - 0028-3770 (Linking)
VI  - 66
IP  - 2
DP  - 2020 Apr
TI  - Cranioplasty for bone defects after craniosynostosis surgery. Case series with 
      literature review.
PG  - 97-101
LID - S0028-3770(20)30031-X [pii]
LID - 10.1016/j.neuchi.2019.10.015 [doi]
AB  - INTRODUCTION: Surgical treatment of craniosynostosis in children may generate 
      secondary cranial vault defects by incomplete ossification process. The incidence 
      of cranial defects after craniosynostosis surgery is poorly reported in the 
      literature with a variable incidence of 0.5% to 18.2%. To better understand the 
      impact and management of the cranial defects after craniosynostosis surgery, we 
      selected and reviewed al cranioplasties that met this criterion between 2002 and 
      2019. PATIENTS AND METHOD: We found 41 patients (28 M and 13 F) operated between 
      January 2002 to January 2019 who underwent cranioplasty for cranial defects 
      secondary to craniosynostosis surgery in the infancy. All patient were at least 5 
      years old (range 5 to 17 years, median 11). The indication was aesthetic in 28 
      patients and for headaches, learning difficulties or changes in the cerebral 
      blood flow in 13 patients. The material used in cranioplasty was the 
      poly-methyl-methacrylate (PMMA) in 40 patients and customized porous 
      hydroxyapatite (CPHA) in 1 patient. RESULTS: The mean follow-up period after 
      cranioplasty was of 37 months (range 2 to 125 months, median of 27 months). In 
      the postoperative period there were no mortality nor neurological complications. 
      There were 3 cases (7%) of superficial local postoperative wound infection but 
      with no evidence of long-term infection. The long-term CT scan follow-up showed 
      no material migration, dislocation or fractures. CONCLUSION: Considering the 
      characteristics of the cranial vault after craniosynostosis surgery the treatment 
      by cranioplasty with heterologous materials appears to be feasible thus avoiding 
      donor site morbidity. For selected cases with small defects, our experience shows 
      that the use of PMMA may be a safe alternative for the cranial vault repair in 
      children older than 5 years.
CI  - Copyright (c) 2020 Elsevier Masson SAS. All rights reserved.
FAU - Szathmari, A
AU  - Szathmari A
AD  - Service de Neurochirurgie Pediatrique, Hopital Femme Mere Enfant, Hospices Civils 
      de Lyon, Universite Claude-Bernard Lyon1, 59, boulevard Pinel, 69677 Bron, cedex, 
      France. Electronic address: alexandru.szathmari@chu-lyon.fr.
FAU - Morgado, A
AU  - Morgado A
AD  - Service de Neurochirurgie Pediatrique, Hopital Femme Mere Enfant, Hospices Civils 
      de Lyon, Universite Claude-Bernard Lyon1, 59, boulevard Pinel, 69677 Bron, cedex, 
      France.
FAU - Beuriat, P A
AU  - Beuriat PA
AD  - Service de Neurochirurgie Pediatrique, Hopital Femme Mere Enfant, Hospices Civils 
      de Lyon, Universite Claude-Bernard Lyon1, 59, boulevard Pinel, 69677 Bron, cedex, 
      France.
FAU - Petrescu, P
AU  - Petrescu P
AD  - Service de Neurochirurgie Pediatrique, Hopital Femme Mere Enfant, Hospices Civils 
      de Lyon, Universite Claude-Bernard Lyon1, 59, boulevard Pinel, 69677 Bron, cedex, 
      France.
FAU - Di Rocco, F
AU  - Di Rocco F
AD  - Service de Neurochirurgie Pediatrique, Hopital Femme Mere Enfant, Hospices Civils 
      de Lyon, Universite Claude-Bernard Lyon1, 59, boulevard Pinel, 69677 Bron, cedex, 
      France.
FAU - Mottolese, C
AU  - Mottolese C
AD  - Service de Neurochirurgie Pediatrique, Hopital Femme Mere Enfant, Hospices Civils 
      de Lyon, Universite Claude-Bernard Lyon1, 59, boulevard Pinel, 69677 Bron, cedex, 
      France.
LA  - eng
PT  - Journal Article
DEP - 20200224
PL  - France
TA  - Neurochirurgie
JT  - Neuro-Chirurgie
JID - 0401057
RN  - 0 (Biocompatible Materials)
RN  - 9011-14-7 (Polymethyl Methacrylate)
RN  - 91D9GV0Z28 (Durapatite)
SB  - IM
MH  - Adolescent
MH  - Biocompatible Materials
MH  - Child
MH  - Child, Preschool
MH  - Craniosynostoses/*surgery
MH  - Durapatite
MH  - Female
MH  - Humans
MH  - Infant
MH  - Male
MH  - Polymethyl Methacrylate
MH  - Plastic Surgery Procedures/*methods
MH  - Retrospective Studies
MH  - Skull/*surgery
MH  - Surgical Wound Infection/epidemiology/therapy
MH  - Treatment Outcome
MH  - Young Adult
OTO - NOTNLM
OT  - Cranial vault defect after craniosynostosis surgery
OT  - Cranioplasty in children
OT  - Custom-made porous hydroxyapatite implant
OT  - Poly-methyl-methacrylate
EDAT- 2020/02/28 06:00
MHDA- 2020/11/11 06:00
CRDT- 2020/02/28 06:00
PHST- 2019/09/21 00:00 [received]
PHST- 2019/10/02 00:00 [revised]
PHST- 2019/10/13 00:00 [accepted]
PHST- 2020/02/28 06:00 [pubmed]
PHST- 2020/11/11 06:00 [medline]
PHST- 2020/02/28 06:00 [entrez]
AID - S0028-3770(20)30031-X [pii]
AID - 10.1016/j.neuchi.2019.10.015 [doi]
PST - ppublish
SO  - Neurochirurgie. 2020 Apr;66(2):97-101. doi: 10.1016/j.neuchi.2019.10.015. Epub 
      2020 Feb 24.