PMID- 32112248
OWN - NLM
STAT- MEDLINE
DCOM- 20210427
LR  - 20210427
IS  - 1128-045X (Electronic)
IS  - 1123-6337 (Linking)
VI  - 24
IP  - 4
DP  - 2020 Apr
TI  - How is your proctology patient really doing? Outcome measurement in proctology: 
      development, design and validation study of the Proctoprom.
PG  - 291-300
LID - 10.1007/s10151-020-02156-2 [doi]
AB  - BACKGROUND: The aim of the present study was to develop and evaluate the 
      reliability and validity of proctology patient-reported outcome measurements 
      (PROM): Proctoprom. METHODS: Development of the Proctoprom was based on interview 
      rounds with experts (n = 4) and patients (n = 19) in open informal interview 
      rounds regarding content and form. Once consensus was achieved on five items, 
      data were collected between July 2014 and August 2016 from 991 patients recruited 
      consecutively in a specialized proctology center. Reliability, construct validity 
      and responsiveness of the PROM were determined through exploratory factor 
      analysis, test-retest analysis and anchor-based hypothesis testing. We also 
      estimated discriminant validity, standard error of measurement (SEM), minimal 
      detectable change (MDC95%) and minimal clinically important difference (MCID). 
      RESULTS: The five items loaded on one factor that reflected good internal 
      consistency (Cronbach's alpha 0.81). Test-retest analysis showed good reliability 
      with intraclass correlation of 0.81. Construct validity measurement resulted in 
      AUCs of 0.85 and 0.90. Responsiveness measurement resulted in AUCs of > 0.76 for 
      both hypotheses. SEM was estimated at 3.0 points and MDC at 4.8 points. We 
      estimated an MCID of 10 points. CONCLUSIONS: Proctoprom is a valid and reliable 
      tool that is responsive to change and that meets consensus-based standards for 
      the selection of health measurement instruments. It can be used to evaluate 
      disease burden and effect of treatment in all adult proctology patients 
      regardless of their proctologic diagnosis.
FAU - Vander Mijnsbrugge, G J
AU  - Vander Mijnsbrugge GJ
AD  - Proctos Kliniek, Bilthoven, The Netherlands. 
      gjh.vandermijnsbrugge@proctoskliniek.com.
FAU - Molenaar, C
AU  - Molenaar C
AD  - Proctos Kliniek, Bilthoven, The Netherlands.
FAU - Buyl, R
AU  - Buyl R
AD  - Vrije Universiteit Brussel, Brussels, Belgium.
FAU - Westert, G
AU  - Westert G
AD  - Radboud University Medical Centre, Radboud Institute of Health Sciences, IQ 
      Healthcare, Nijmegen, The Netherlands.
FAU - van der Wees, P J
AU  - van der Wees PJ
AD  - Radboud University Medical Centre, Radboud Institute of Health Sciences, IQ 
      Healthcare, Nijmegen, The Netherlands.
LA  - eng
PT  - Journal Article
DEP - 20200228
PL  - Italy
TA  - Tech Coloproctol
JT  - Techniques in coloproctology
JID - 9613614
SB  - IM
MH  - Adult
MH  - *Colorectal Surgery
MH  - Humans
MH  - Patient Reported Outcome Measures
MH  - Reproducibility of Results
MH  - Surveys and Questionnaires
OTO - NOTNLM
OT  - Colorectal surgery
OT  - Patient reported outcome measures
OT  - Proctology
EDAT- 2020/03/01 06:00
MHDA- 2021/04/28 06:00
CRDT- 2020/03/01 06:00
PHST- 2019/06/11 00:00 [received]
PHST- 2020/01/31 00:00 [accepted]
PHST- 2020/03/01 06:00 [pubmed]
PHST- 2021/04/28 06:00 [medline]
PHST- 2020/03/01 06:00 [entrez]
AID - 10.1007/s10151-020-02156-2 [pii]
AID - 10.1007/s10151-020-02156-2 [doi]
PST - ppublish
SO  - Tech Coloproctol. 2020 Apr;24(4):291-300. doi: 10.1007/s10151-020-02156-2. Epub 
      2020 Feb 28.