PMID- 32121316
OWN - NLM
STAT- MEDLINE
DCOM- 20201119
LR  - 20240328
IS  - 1660-3397 (Electronic)
IS  - 1660-3397 (Linking)
VI  - 18
IP  - 3
DP  - 2020 Feb 29
TI  - Application of Gelatin Decorated with Allura Red as Resonance Rayleigh Scattering 
      Sensor to Detect Chito-Oligosaccharides.
LID - 10.3390/md18030146 [doi]
LID - 146
AB  - A convenient and sensitive triple-wavelength overlapping resonance Rayleigh 
      scattering (TWO-RRS) method for the detection of chito-oligosaccharides (COS) was 
      proposed based on enhancing the rigid surface of porous reticular spatial 
      structure of gelatin and COS by introducing allura red AC (AR). The interaction 
      and resultant porous reticular spatial structure were characterized with 
      transmission electron microscopy (TEM), RRS, and UV-Vis spectroscopy. The results 
      indicated that gelatin and COS formed porous reticular spatial structure with an 
      average diameter of 1.5-2.0 mum, and the RRS value of COS-AR-gelatin ternary 
      system with gelatin participation was significantly higher than that of COS-AR 
      binary system. Under the optimal conditions, the enhanced TWO-RRS intensity of 
      the system was linearly proportional to COS concentration in the range of 
      0.30-2.50 mug/mL, and the regression equation was DeltaI = 4933.2c-446.21 with R(2) = 
      0.9980. The limit of detection was 0.0478 mug/mL. So, a new method for the 
      detection of COS was established and verified in the health products with 
      satisfactory results.
FAU - Zou, Weiling
AU  - Zou W
AD  - School of Public Health, Guangdong Pharmaceutical University, Guangzhou 510310, 
      Guangdong, China.
FAU - Sun, Zijun
AU  - Sun Z
AD  - School of Public Health, Guangdong Pharmaceutical University, Guangzhou 510310, 
      Guangdong, China.
FAU - Su, Zhengquan
AU  - Su Z
AD  - Guangdong Engineering Research Center of Natural Products and New Drugs, 
      Guangdong Provincial University Engineering Technology Research Center of Natural 
      Products and Drugs, Guangdong Pharmaceutical University, Guangzhou 510006, China.
FAU - Bai, Yan
AU  - Bai Y
AD  - School of Public Health, Guangdong Pharmaceutical University, Guangzhou 510310, 
      Guangdong, China.
LA  - eng
GR  - No. 201804010329/the Industry University Research Collaborative Innovation Major 
      Projects of Guangzhou Science Technology Innovation Commission, China/
GR  - No. 2018A0303130079/the National Natural Science Foundation of Guangdong, China/
GR  - No. 2017GCZX002/Guangdong Provincial University Engineering Technology Research 
      Center of Natural Products and Drugs/
GR  - No. 2016KTSCX065/the Innovation strong school project of the Guangdong 
      Pharmaceutical University, China/
GR  - No. 201604020164/the Industry University Research Collaborative Innovation Major 
      Projects of Guangzhou Science Technology Innovation Commission, China/
PT  - Journal Article
DEP - 20200229
PL  - Switzerland
TA  - Mar Drugs
JT  - Marine drugs
JID - 101213729
RN  - 0 (Azo Compounds)
RN  - 0 (Oligosaccharides)
RN  - 1398-61-4 (Chitin)
RN  - 25956-17-6 (Allura Red AC Dye)
RN  - 9000-70-8 (Gelatin)
SB  - IM
MH  - Animals
MH  - Azo Compounds
MH  - Chitin/*chemistry
MH  - Gelatin/*chemistry
MH  - Oligosaccharides/*chemistry
MH  - Spectrometry, Fluorescence
PMC - PMC7143526
OTO - NOTNLM
OT  - allura red AC
OT  - chito-oligosaccharides
OT  - gelatin
OT  - triple-wavelength overlapping resonance Rayleigh scattering
COIS- The authors declare that they have no known competing financial interests or 
      personal relationships that could have appeared to influence the work reported in 
      this paper.
EDAT- 2020/03/04 06:00
MHDA- 2020/11/20 06:00
PMCR- 2020/03/01
CRDT- 2020/03/04 06:00
PHST- 2020/01/11 00:00 [received]
PHST- 2020/02/23 00:00 [revised]
PHST- 2020/02/24 00:00 [accepted]
PHST- 2020/03/04 06:00 [entrez]
PHST- 2020/03/04 06:00 [pubmed]
PHST- 2020/11/20 06:00 [medline]
PHST- 2020/03/01 00:00 [pmc-release]
AID - md18030146 [pii]
AID - marinedrugs-18-00146 [pii]
AID - 10.3390/md18030146 [doi]
PST - epublish
SO  - Mar Drugs. 2020 Feb 29;18(3):146. doi: 10.3390/md18030146.