PMID- 3212281 OWN - NLM STAT- MEDLINE DCOM- 19890223 LR - 20221222 IS - 0034-5288 (Print) IS - 0034-5288 (Linking) VI - 45 IP - 3 DP - 1988 Nov TI - Mechanics of breathing in goats. PG - 332-6 AB - Common pulmonary function tests used in man and domestic mammals were adapted to the goat. Requirements for intrathoracic pressure record and pulmonary function investigation were determined. The elastance of the mid-thoracic portion of the oesophagus was measured in 17 healthy goats. The calculated percentage error in identifying the endoesophageal intrathoracic pressure decreased with somatic growth, and was found to be smaller than 2 per cent for adult goats. The location of the oesophageal balloon catheter used to measure the intrathoracic pressure was standardised. The following regression equation calculated between the length of catheter (Lcat) and the thoracic circumference (TC) was found: Lcat (cm) = 6.19 +/- 0.7163 X TC (cm) (R2 = 0.96). The influence of the dead space of a face mask on respiration pattern and arterial blood gas were studied. There were no significant changes in arterial partial pressure of oxygen (PaO2) and carbon dioxide (PaCO2), pHa, breathing frequency and intrathoracic pressures. The influence of head and neck position was investigated. Upper airway resistance (Ruaw), measured with the head in a normal position did not significantly differ from values obtained with the head in a horizontal position. Ruaw measured with the head in a vertical position was considerably increased. Arterial blood gas tension and pulmonary mechanics were measured to assess the reproducibility of pulmonary function measurements. Variability in blood gas tension, tidal volume and minute volume is small. The variability of peak to peak intrathoracic pressure change (max delta Plp), dynamic lung compliance (Cdyn), total pulmonary resistance (RL) and Rt were relatively large. FAU - Bakima, M AU - Bakima M AD - Service de Pathologie Medicale, Faculte de Medecine Veterinaire, Universite de Liege, Brussels, Belgium. FAU - Gustin, P AU - Gustin P FAU - Lekeux, P AU - Lekeux P FAU - Lomba, F AU - Lomba F LA - eng PT - Journal Article PL - England TA - Res Vet Sci JT - Research in veterinary science JID - 0401300 SB - IM MH - Airway Resistance/veterinary MH - Animals MH - Esophagus/physiology MH - Goats/*physiology MH - Lung Compliance/veterinary MH - Pressure MH - *Respiration MH - Respiratory Function Tests/veterinary EDAT- 1988/11/01 00:00 MHDA- 1988/11/01 00:01 CRDT- 1988/11/01 00:00 PHST- 1988/11/01 00:00 [pubmed] PHST- 1988/11/01 00:01 [medline] PHST- 1988/11/01 00:00 [entrez] PST - ppublish SO - Res Vet Sci. 1988 Nov;45(3):332-6.