PMID- 32126040
OWN - NLM
STAT- MEDLINE
DCOM- 20210212
LR  - 20210212
IS  - 1873-4502 (Electronic)
IS  - 0886-3350 (Linking)
VI  - 46
IP  - 2
DP  - 2020 Feb
TI  - Evolution of visual acuity, flap thickness, and optical density after laser in 
      situ keratomileusis performed with a femtosecond laser.
PG  - 260-266
LID - 10.1097/j.jcrs.0000000000000008 [doi]
AB  - PURPOSE: To describe the postoperative evolution of visual acuity, flap 
      morphology, and stromal optical density femtosecond laser-assisted laser in situ 
      keratomileusis (FS-LASIK). SETTING: Clinica Rementeria, Madrid, Spain. DESIGN: 
      Prospective case series. METHODS: The study comprised 44 consecutive eyes that 
      had FS-LASIK performed with the WaveLight FS200 and the Allegretto excimer laser 
      to correct myopia. Visual outcomes, flap thickness, and stromal optical density 
      were assessed 1 day, 1 week, 1 month, and 3 months postoperatively. RESULTS: A 
      statistically significant improvement in the mean uncorrected distance visual 
      acuity at 1 day (0.94 +/- 0.2) and 1 week (0.93 +/- 0.2) to 1 month (1.04 +/- 0.2) and 
      3 months (1.11 +/- 0.1) postoperatively (P < .05). At 3 months postoperatively, the 
      femtosecond laser had good outcomes in efficacy (0.98 +/- 0.1), safety (0.98 +/- 
      0.1), and predictability (100% of eyes were within +/- 0.5 D of emmetropia). The 
      femtosecond-created flaps were slightly thicker than intended, the mean SD 
      intraflap was 7.1 mum, the range between the thickest and thinnest points in each 
      flap was 25.4 mum, and the mean flap thickness homogeneity was 7.6 mum at 3 months 
      postoperatively. A progressive decrease in the optical density of the flap stroma 
      and the residual stromal bed was detected during follow-up. CONCLUSIONS: The 
      femtosecond laser study appears to be a safe, effective, and predictable platform 
      to obtain LASIK flaps. The flaps were planar and homogeneous but slightly thicker 
      than intended. The optical density of the flap stroma was slightly higher at 
      early follow-up and decreased over time.
FAU - Parafita-Fernandez, Alberto
AU  - Parafita-Fernandez A
AD  - From Complexo Hospitalario Universitario de Pontevedra (Parafita-Fernandez), 
      Pontevedra, Clinica Oftalmologica Dr Parafita (Parafita-Fernandez), Ribeira, 
      Clinica Rementeria (Garcia-Gonzalez, Gros-Otero, Alvarez-Rementeria Capelo; 
      Blazquez Sanchez), Madrid, Clinica Novovision (Garcia-Gonzalez, Teus), Madrid, 
      Universidad Europea de Madrid (Garcia-Gonzalez), Madrid, Universidad Complutense 
      de Madrid, Madrid (Blazquez Sanchez), and Hospital Universitario Principe de 
      Asturias, University of Alcala (Teus), Alcala de Henares, Madrid, Spain.
FAU - Garcia-Gonzalez, Montserrat
AU  - Garcia-Gonzalez M
FAU - Gros-Otero, Juan
AU  - Gros-Otero J
FAU - Alvarez-Rementeria Capelo, Laureano
AU  - Alvarez-Rementeria Capelo L
FAU - Blazquez Sanchez, Vanesa
AU  - Blazquez Sanchez V
FAU - Teus, Miguel
AU  - Teus M
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Cataract Refract Surg
JT  - Journal of cataract and refractive surgery
JID - 8604171
SB  - IM
MH  - Adult
MH  - Corneal Pachymetry
MH  - Corneal Stroma/surgery
MH  - Female
MH  - Humans
MH  - Keratomileusis, Laser In Situ/*methods
MH  - Lasers, Excimer/*therapeutic use
MH  - Male
MH  - Middle Aged
MH  - Myopia/physiopathology/*surgery
MH  - Organ Size
MH  - Prospective Studies
MH  - Refraction, Ocular/physiology
MH  - Surgical Flaps/*pathology
MH  - Tomography, Optical Coherence
MH  - Treatment Outcome
MH  - Visual Acuity/*physiology
MH  - Young Adult
EDAT- 2020/03/04 06:00
MHDA- 2021/02/13 06:00
CRDT- 2020/03/04 06:00
PHST- 2020/03/04 06:00 [entrez]
PHST- 2020/03/04 06:00 [pubmed]
PHST- 2021/02/13 06:00 [medline]
AID - 02158034-202002000-00015 [pii]
AID - 10.1097/j.jcrs.0000000000000008 [doi]
PST - ppublish
SO  - J Cataract Refract Surg. 2020 Feb;46(2):260-266. doi: 
      10.1097/j.jcrs.0000000000000008.