PMID- 32133951
OWN - NLM
STAT- MEDLINE
DCOM- 20210614
LR  - 20210614
IS  - 1573-4056 (Electronic)
VI  - 16
IP  - 3
DP  - 2020
TI  - Evaluation of LVDD by CCTA with Dual-source CT in Type 2 Diabetes Mellitus 
      Patients.
PG  - 214-223
LID - 10.2174/1573405615666191126101454 [doi]
AB  - BACKGROUND: Left ventricular diastolic dysfunction (LVDD) is a common abnormality 
      among patients in T2DM. AIMS: We aimed to evaluate the feasibility of coronary 
      computed tomography angiography (CCTA) for the assessment of LVDD in type 2 
      diabetes mellitus (T2DM) patients. METHODS: 80 consecutive T2DM patients who were 
      referred for a clinically dual-source CCTA examination to evaluate suspected 
      coronary artery disease and also underwent 2D echocardiography within 7 days of 
      CCTA inclusion and exclusion criteria, were performed. Correlation between CCTA 
      and echocardiography was tested through linear regression and Bland-Altman 
      analysis. RESULTS: In total, 60 T2DM patients were included for the analysis. 
      Pearson correlation showed good correlation for E (r = 0.28; P = 0.028), E/A (r = 
      0.69; P < 0.01); E (r = -0.06; P = 0.776), E/A (r = 0.54; P = 0.003) and E (r = 
      0.64; P < 0.01), E/A (r = 0.83; P < 0.01) in three groups, respectively. Overall, 
      diagnostic accuracy for assessment in CCTA of diastolic dysfunction was 79.76% 
      (95% CI: 68%-91%), 71.43% (95% CI: 58%-85%) and 87.50 (95% CI: 79%-96%) in three 
      groups. CONCLUSION: The presented study proved that CCTA showed good correlations 
      in the estimation of LV filling pressures compared with echocardiography in T2DM 
      patients. Accordingly, retrospectively ECG-gated CCTA may provide valuable 
      information on the evaluation of LVDD in T2DM patients.
CI  - Copyright(c) Bentham Science Publishers; For any queries, please email at 
      epub@benthamscience.net.
FAU - Huang, Zengfa
AU  - Huang Z
AD  - Department of Radiology, Tongji Medical College, Huazhong University of Science 
      and Technology, The Central Hospital of Wuhan, Wuhan, China.
FAU - Xiao, Jianwei
AU  - Xiao J
AD  - Department of Radiology, Tongji Medical College, Huazhong University of Science 
      and Technology, The Central Hospital of Wuhan, Wuhan, China.
FAU - Li, Zuoqin
AU  - Li Z
AD  - Department of Radiology, Tongji Medical College, Huazhong University of Science 
      and Technology, The Central Hospital of Wuhan, Wuhan, China.
FAU - Hu, Yun
AU  - Hu Y
AD  - Department of Radiology, Tongji Medical College, Huazhong University of Science 
      and Technology, The Central Hospital of Wuhan, Wuhan, China.
FAU - Xie, Yuanliang
AU  - Xie Y
AD  - Department of Radiology, Tongji Medical College, Huazhong University of Science 
      and Technology, The Central Hospital of Wuhan, Wuhan, China.
FAU - Zhang, Shutong
AU  - Zhang S
AD  - Department of Radiology, Tongji Medical College, Huazhong University of Science 
      and Technology, The Central Hospital of Wuhan, Wuhan, China.
FAU - Wang, Xiang
AU  - Wang X
AD  - Department of Radiology, Tongji Medical College, Huazhong University of Science 
      and Technology, The Central Hospital of Wuhan, Wuhan, China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United Arab Emirates
TA  - Curr Med Imaging
JT  - Current medical imaging
JID - 101762461
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Computed Tomography Angiography/instrumentation/*methods
MH  - Coronary Angiography/instrumentation/*methods
MH  - Diabetes Mellitus, Type 2/*complications/physiopathology
MH  - Feasibility Studies
MH  - Female
MH  - Heart Ventricles/diagnostic imaging
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Reproducibility of Results
MH  - Ventricular Dysfunction, Left/*complications/*diagnostic imaging/physiopathology
OTO - NOTNLM
OT  - Coronary computed tomography angiography
OT  - cardiovascular disease
OT  - echocardiography
OT  - left ventricular diastolic dysfunction
OT  - patients
OT  - type 2 diabetes mellitus.
EDAT- 2020/03/07 06:00
MHDA- 2021/06/16 06:00
CRDT- 2020/03/06 06:00
PHST- 2019/08/03 00:00 [received]
PHST- 2019/11/02 00:00 [revised]
PHST- 2019/11/19 00:00 [accepted]
PHST- 2020/03/06 06:00 [entrez]
PHST- 2020/03/07 06:00 [pubmed]
PHST- 2021/06/16 06:00 [medline]
AID - CMIR-EPUB-102603 [pii]
AID - 10.2174/1573405615666191126101454 [doi]
PST - ppublish
SO  - Curr Med Imaging. 2020;16(3):214-223. doi: 10.2174/1573405615666191126101454.