PMID- 32140027 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20200928 IS - 0976-3147 (Print) IS - 0976-3155 (Electronic) IS - 0976-3155 (Linking) VI - 11 IP - 1 DP - 2020 Jan TI - Spontaneous Epidural Hematoma of the Cervical Spine Following Thrombolysis in a Patient with STEMI-Two Medical Specialties Facing a Rare Dilemma. PG - 191-195 LID - 10.1055/s-0039-3400182 [doi] AB - Spontaneous spinal epidural hematoma (SSEH) is a rare, albeit well-documented complication following thrombolysis treatment in ST elevation myocardial infarction (STEMI). A SSEH usually manifests with cervical pain and neurologic deficits and may require surgical intervention. In this case report, we present the first reported SSEH to occur following thrombolysis with reteplase. In this case, the SSEH manifested with cervical pain shortly after the patient emerged from his rescue percutaneous coronary intervention (PCI). Although magnetic resonance imaging reported spinal cord compression, the lack of neurologic symptoms prompted the treating clinicians to delay surgery. A dangerous dilemma emerged, as the usual antithrombotic regimen that was necessary to avoid stent thrombosis post-PCI, was also likely to exacerbate the bleeding. As a compromise, the patient only received aspirin as a single antiplatelet therapy. Ultimately, the patient responded well to conservative treatment, with the hematoma stabilizing a week later, without residual neurologic deficits. In conclusion, the conservative treatment of SSEH appears to be an acceptable option for carefully selected patients, but the risks of permanent neurologic deficits and stent thrombosis have to be weighted for each patient. FAU - Tsarouchas, Anastasios AU - Tsarouchas A AD - 3rd Cardiology Department, Hippokrateio University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece. FAU - Mouselimis, Dimitrios AU - Mouselimis D AD - 3rd Cardiology Department, Hippokrateio University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece. FAU - Bakogiannis, Constantinos AU - Bakogiannis C AD - 3rd Cardiology Department, Hippokrateio University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece. FAU - Gkasdaris, Grigorios AU - Gkasdaris G AD - Department of Neurosurgery, KAT General Hospital of Attica, Athens, Greece. FAU - Dimitriadis, George AU - Dimitriadis G AD - General Hospital of Katerini, Katerini, Greece. FAU - Zioutas, Dimitrios AU - Zioutas D AD - St. Luke's Hospital, Thessaloniki, Greece. FAU - Papadopoulos, Christodoulos E AU - Papadopoulos CE AD - 3rd Cardiology Department, Hippokrateio University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece. LA - eng PT - Case Reports DEP - 20191205 PL - United States TA - J Neurosci Rural Pract JT - Journal of neurosciences in rural practice JID - 101533710 PMC - PMC7055631 OTO - NOTNLM OT - ST elevation myocardial infarction OT - cervical spine OT - spinal epidural hematoma OT - spontaneous spinal epidural hematoma OT - thrombolysis COIS- Conflict of Interest None declared. EDAT- 2020/03/07 06:00 MHDA- 2020/03/07 06:01 PMCR- 2020/01/01 CRDT- 2020/03/07 06:00 PHST- 2020/03/07 06:00 [entrez] PHST- 2020/03/07 06:00 [pubmed] PHST- 2020/03/07 06:01 [medline] PHST- 2020/01/01 00:00 [pmc-release] AID - JNRP1900212 [pii] AID - 10.1055/s-0039-3400182 [doi] PST - ppublish SO - J Neurosci Rural Pract. 2020 Jan;11(1):191-195. doi: 10.1055/s-0039-3400182. Epub 2019 Dec 5.