PMID- 32143875
OWN - NLM
STAT- MEDLINE
DCOM- 20200713
LR  - 20200911
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1620
DP  - 2020 Jun 7
TI  - Residue analysis of fungicides fenpicoxamid, isofetamid, and mandestrobin in 
      cereals using zirconium oxide disposable pipette extraction clean-up and 
      ultrahigh-performance liquid chromatography-tandem mass spectrometry.
PG  - 461004
LID - S0021-9673(20)30210-7 [pii]
LID - 10.1016/j.chroma.2020.461004 [doi]
AB  - In the present study, a fast multiresidue method determining three novel 
      fungicides fenpicoxamid, isofetamid, and mandestrobin in cereals was developed 
      and validated for the first time using ultrahigh-performance liquid 
      chromatography coupled to tandem mass spectrometry (UHPLC-MS/MS). Samples were 
      extracted by QuEChERS (Quick, Easy, Cheap, Effective, Rugged, and Safe) 
      methodology, and cleaned up using the disposable pipette extraction (DPX) tips 
      containing primary secondary amine (PSA) and silica gel modified with zirconium 
      oxide (Z-Sep) in less than 1 min. Linearity (r > 0.99) of three fungicides in the 
      calibration range of 0.001-0.1 microg mL(-1) was satisfactory. Mean recoveries 
      (n = 15) from all matrices were between 84.8% and 100.3% as the corresponding 
      intra-day and inter-day relative standard deviations (RSDs) were less than 10.6%. 
      Limits of quantitation (LOQs) of all analytes in different matrices were defined 
      at 0.01 mg kg(-1). The results indicate this method can serve as a sensitive and 
      rapid approach to monitoring contents of fenpicoxamid, isofetamid, and 
      mandestrobin in cereals.
CI  - Copyright (c) 2020 Elsevier B.V. All rights reserved.
FAU - Lu, Zhou
AU  - Lu Z
AD  - Laboratory of Quality & Safety Risk Assessment for Ginseng and Antler Products, 
      Jilin Agricultural University, Changchun, Jilin 130118, China.
FAU - Fang, Nan
AU  - Fang N
AD  - College of Plant Protection, Jilin Agricultural University, Changchun, Jilin 
      130118, China.
FAU - Zhang, Zhongbei
AU  - Zhang Z
AD  - College of Plant Protection, Jilin Agricultural University, Changchun, Jilin 
      130118, China.
FAU - Hou, Zhiguang
AU  - Hou Z
AD  - College of Plant Protection, Jilin Agricultural University, Changchun, Jilin 
      130118, China.
FAU - Lu, Zhongbin
AU  - Lu Z
AD  - College of Plant Protection, Jilin Agricultural University, Changchun, Jilin 
      130118, China.
FAU - Li, Yueru
AU  - Li Y
AD  - Laboratory of Quality & Safety Risk Assessment for Ginseng and Antler Products, 
      Jilin Agricultural University, Changchun, Jilin 130118, China. Electronic 
      address: liyuerusr@163.com.
LA  - eng
PT  - Journal Article
PT  - Validation Study
DEP - 20200228
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Acetamides)
RN  - 0 (Fungicides, Industrial)
RN  - 0 (Lactones)
RN  - 0 (Pesticide Residues)
RN  - 0 (Pyridines)
RN  - 0 (Thiophenes)
RN  - 0 (UK 2A)
RN  - 0 (mandestrobin)
RN  - 95499Z1H0H (isofetamid)
RN  - C6V6S92N3C (Zirconium)
RN  - S38N85C5G0 (zirconium oxide)
SB  - IM
MH  - Acetamides/*analysis
MH  - Chemical Fractionation/instrumentation
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Edible Grain/*chemistry
MH  - Fungicides, Industrial/*analysis/chemistry/isolation & purification
MH  - Lactones/analysis/chemistry/isolation & purification
MH  - Pesticide Residues/*analysis/chemistry/isolation & purification
MH  - Pyridines/analysis/chemistry/isolation & purification
MH  - Tandem Mass Spectrometry/*methods
MH  - Thiophenes/*analysis
MH  - Zirconium/chemistry
OTO - NOTNLM
OT  - Cereals
OT  - DPX
OT  - Fenpicoxamid
OT  - Isofetamid
OT  - Mandestrobin
OT  - UHPLC-MS/MS
COIS- Declaration of Competing Interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2020/03/08 06:00
MHDA- 2020/07/14 06:00
CRDT- 2020/03/08 06:00
PHST- 2019/12/04 00:00 [received]
PHST- 2020/02/19 00:00 [revised]
PHST- 2020/02/27 00:00 [accepted]
PHST- 2020/03/08 06:00 [pubmed]
PHST- 2020/07/14 06:00 [medline]
PHST- 2020/03/08 06:00 [entrez]
AID - S0021-9673(20)30210-7 [pii]
AID - 10.1016/j.chroma.2020.461004 [doi]
PST - ppublish
SO  - J Chromatogr A. 2020 Jun 7;1620:461004. doi: 10.1016/j.chroma.2020.461004. Epub 
      2020 Feb 28.