PMID- 32146385
OWN - NLM
STAT- MEDLINE
DCOM- 20200430
LR  - 20200430
IS  - 1873-3700 (Electronic)
IS  - 0031-9422 (Linking)
VI  - 174
DP  - 2020 Jun
TI  - Characterization of phytochemicals in the roots of wild herbaceous peonies from 
      China and screening for medicinal resources.
PG  - 112331
LID - S0031-9422(19)31149-5 [pii]
LID - 10.1016/j.phytochem.2020.112331 [doi]
AB  - Paeonia Radix Rubra (PRR) is a very common traditional Chinese medicine (TCM). 
      The roots of Paeonia lactiflora and Paeonia anomala subsp. veitchii are used for 
      the production of PRR. However, other species of section Paeonia in China are 
      also used to produce PRR. The roots of section Paeonia from 20 populations of 
      seven species and two subspecies in China were analyzed by high performance 
      liquid chromatography quadrupole time-of-flight mass spectrometry (HPLC-Q-TOF- 
      MS). A total of 21 metabolites were identified, including nine monoterpene 
      glycosides, seven tannins, three phenols, one paeonol and one flavonoid. There 
      were significant differences in the composition and content of metabolites among 
      different populations. The relative contents of monoterpene glycosides and 
      tannins were generally higher in most samples. Cluster analysis showed that 20 
      populations could be divided into four groups. Among them, the populations of P. 
      lactiflora and Paeonia mairei were clustered together in one group. The content 
      of paeoniflorin in P. lactiflora was high (>22.20 mg g(-1), dry weight, the same 
      below), and the content of lactiflorin in P. mairei (>17.50 mg g(-1)) was 
      significantly higher than in other species (<2.30 mg g(-1)). The monoterpene 
      glycoside content in P. mairei (>51.60 mg g(-1)) was significantly higher than in 
      other species (<43.40 mg g(-1)), suggesting that it could be useful medicinal 
      germplasm for the development of monoterpene glycosides. In addition, some 
      populations of Paeonia emodi, Paeonia sterniana and P. mairei may also be used as 
      potential germplasm resources for use in PRR. Genetic and environmental factors 
      resulted in differences in the composition and content of metabolites in 
      different populations of the same species. Therefore, it is necessary to 
      carefully consider the origin of Paeonia germplasm when selecting medicinal 
      materials to be used as resources for the production of PRR.
CI  - Copyright (c) 2020 Elsevier Ltd. All rights reserved.
FAU - Yang, Yong
AU  - Yang Y
AD  - College of Landscape Architecture, Beijing Forestry University, Beijing Key 
      Laboratory of Ornamental Plants Germplasm Innovation and Molecular Breeding, 
      National Engineering Research Center for Floriculture, Beijing, 100083, China; 
      Key Laboratory of Plant Resources/Beijing Botanical Garden, Institute of Botany, 
      Chinese Academy of Sciences, Beijing, 100093, China.
FAU - Li, Shan-Shan
AU  - Li SS
AD  - Key Laboratory of Plant Resources/Beijing Botanical Garden, Institute of Botany, 
      Chinese Academy of Sciences, Beijing, 100093, China; University of Chinese 
      Academy of Sciences, Beijing, 100049, China.
FAU - Teixeira da Silva, Jaime A
AU  - Teixeira da Silva JA
AD  - P. O. Box 7, Miki-cho Post Office, Ikenobe 3011-2, Kagawa-ken, 761-0799, Japan.
FAU - Yu, Xiao-Nan
AU  - Yu XN
AD  - College of Landscape Architecture, Beijing Forestry University, Beijing Key 
      Laboratory of Ornamental Plants Germplasm Innovation and Molecular Breeding, 
      National Engineering Research Center for Floriculture, Beijing, 100083, China. 
      Electronic address: yuxiaonan626@126.com.
FAU - Wang, Liang-Sheng
AU  - Wang LS
AD  - Key Laboratory of Plant Resources/Beijing Botanical Garden, Institute of Botany, 
      Chinese Academy of Sciences, Beijing, 100093, China; University of Chinese 
      Academy of Sciences, Beijing, 100049, China. Electronic address: 
      wanglsh@ibcas.ac.cn.
LA  - eng
PT  - Journal Article
DEP - 20200305
PL  - England
TA  - Phytochemistry
JT  - Phytochemistry
JID - 0151434
RN  - 0 (Drugs, Chinese Herbal)
RN  - 0 (Monoterpenes)
RN  - 0 (Phytochemicals)
SB  - IM
MH  - China
MH  - *Drugs, Chinese Herbal
MH  - Monoterpenes
MH  - *Paeonia
MH  - Phytochemicals
MH  - Plant Roots
OTO - NOTNLM
OT  - HPLC
OT  - Monoterpene glycosides
OT  - Paeonia spp.
OT  - Paeoniaceae
OT  - Peony roots
OT  - Tannin
OT  - Wild resources
COIS- Declaration of competing interest The authors declare no conflicts of interest. 
      The authors declare that they have no known competing financial interests or 
      personal relationships that could have appeared to influence the work reported in 
      this paper.
EDAT- 2020/03/09 06:00
MHDA- 2020/05/01 06:00
CRDT- 2020/03/09 06:00
PHST- 2019/12/01 00:00 [received]
PHST- 2020/02/25 00:00 [revised]
PHST- 2020/02/25 00:00 [accepted]
PHST- 2020/03/09 06:00 [pubmed]
PHST- 2020/05/01 06:00 [medline]
PHST- 2020/03/09 06:00 [entrez]
AID - S0031-9422(19)31149-5 [pii]
AID - 10.1016/j.phytochem.2020.112331 [doi]
PST - ppublish
SO  - Phytochemistry. 2020 Jun;174:112331. doi: 10.1016/j.phytochem.2020.112331. Epub 
      2020 Mar 5.