PMID- 32149131
OWN - NLM
STAT- MEDLINE
DCOM- 20201207
LR  - 20240328
IS  - 2314-6141 (Electronic)
IS  - 2314-6133 (Print)
VI  - 2020
DP  - 2020
TI  - Adipogenesis Regulation and Endocrine Disruptors: Emerging Insights in Obesity.
PG  - 7453786
LID - 10.1155/2020/7453786 [doi]
LID - 7453786
AB  - Endocrine disruptors (EDs) are defined as environmental pollutants capable of 
      interfering with the functioning of the hormonal system. They are environmentally 
      distributed as synthetic fertilizers, electronic waste, and several food 
      additives that are part of the food chain. They can be considered as obesogenic 
      compounds since they have the capacity to influence cellular events related to 
      adipose tissue, altering lipid metabolism and adipogenesis processes. This review 
      will present the latest scientific evidence of different EDs such as persistent 
      organic pollutants (POPs), heavy metals, "nonpersistent" phenolic compounds, 
      triclosan, polybrominated diphenyl ethers (PBDEs), and smoke-derived compounds 
      (benzo -alpha-pyrene) and their influence on the differentiation processes 
      towards adipocytes in both in vitro and in vivo models.
CI  - Copyright (c) 2020 Jorge Enrique Gonzalez-Casanova et al.
FAU - Gonzalez-Casanova, Jorge Enrique
AU  - Gonzalez-Casanova JE
AUID- ORCID: 0000-0002-8071-6003
AD  - Instituto de Ciencias Biomedicas, Facultad de Ciencias de la Salud, Universidad 
      Autonoma de Chile, Santiago, Chile.
FAU - Pertuz-Cruz, Sonia Liliana
AU  - Pertuz-Cruz SL
AD  - Programa de Nutricion y Dietetica, Departamento de Nutricion Humana, Facultad de 
      Medicina, Universidad Nacional de Colombia, Bogota, Colombia.
FAU - Caicedo-Ortega, Nelson Hernando
AU  - Caicedo-Ortega NH
AD  - Departamento de Ingenieria Bioquimica, Facultad de Ingenieria, Universidad ICESI, 
      Cali, Colombia.
FAU - Rojas-Gomez, Diana Marcela
AU  - Rojas-Gomez DM
AUID- ORCID: 0000-0002-6956-6315
AD  - Escuela de Nutricion y Dietetica, Facultad de Medicina, Universidad Andres Bello, 
      Santiago, Chile.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20200218
PL  - United States
TA  - Biomed Res Int
JT  - BioMed research international
JID - 101600173
RN  - 0 (Benzoates)
RN  - 0 (Endocrine Disruptors)
RN  - 0 (Environmental Pollutants)
RN  - 0 (Halogenated Diphenyl Ethers)
RN  - 0 (Phenols)
RN  - 0 (Polycyclic Aromatic Hydrocarbons)
RN  - 0 (Pyrenes)
RN  - 0 (Transcription Factors)
RN  - 4NM5039Y5X (Triclosan)
RN  - 9E0T7WFW93 (pyrene)
SB  - IM
MH  - Adipocytes/metabolism
MH  - Adipogenesis/*physiology
MH  - Adipose Tissue/metabolism
MH  - Animals
MH  - Benzoates/metabolism
MH  - Endocrine Disruptors/*metabolism
MH  - Environmental Pollutants/metabolism
MH  - Halogenated Diphenyl Ethers/metabolism
MH  - Humans
MH  - Lipid Metabolism
MH  - Obesity/*metabolism
MH  - Phenols/pharmacology
MH  - Polycyclic Aromatic Hydrocarbons/metabolism
MH  - Pyrenes/metabolism
MH  - Transcription Factors
MH  - Triclosan/metabolism
PMC - PMC7049431
COIS- The authors declare that they have no conflicts of interest.
EDAT- 2020/03/10 06:00
MHDA- 2020/12/15 06:00
PMCR- 2020/02/18
CRDT- 2020/03/10 06:00
PHST- 2019/08/24 00:00 [received]
PHST- 2019/12/03 00:00 [revised]
PHST- 2019/12/12 00:00 [accepted]
PHST- 2020/03/10 06:00 [entrez]
PHST- 2020/03/10 06:00 [pubmed]
PHST- 2020/12/15 06:00 [medline]
PHST- 2020/02/18 00:00 [pmc-release]
AID - 10.1155/2020/7453786 [doi]
PST - epublish
SO  - Biomed Res Int. 2020 Feb 18;2020:7453786. doi: 10.1155/2020/7453786. eCollection 
      2020.