PMID- 32153001
OWN - NLM
STAT- MEDLINE
DCOM- 20210113
LR  - 20210113
IS  - 2543-6031 (Electronic)
IS  - 2451-4934 (Linking)
VI  - 88
IP  - 1
DP  - 2020
TI  - Differences in right ventricular dysfunction in patients with idiopathic 
      pulmonary hypertension versus secondary pulmonary hypertension.
PG  - 1-5
LID - 10.5603/ARM.2020.0071 [doi]
AB  - INTRODUCTION: Right ventricular (RV) function in the setting of pulmonary 
      hypertension based on different etiologies has not been well studied. In this 
      study, we evaluated the RV function in patients with idiopathic pulmonary 
      hypertension (IPH) versus secon-dary pulmonary hypertension (SPH) due to 
      congestive heart failure. MATERIAL AND METHOD: Forty-five patients with pulmonary 
      hypertension and New York Heart Association (NYHA) functional class II or III 
      were enrolled. Of these, 22 were diagnosed with IPH and 23 with SPH. 
      Echocardiographic data, including Doppler and Doppler based strain, were assessed 
      according to the American Society of Echocardiography (ASE) guidelines for 
      detailed evaluation of RV function in these two groups. RESULTS: Mean PAP was 60 
      +/- 14.5 mm Hg in patients with IPH versus 43 +/- 11.5 mm Hg in patients with SPH (p 
      = 0.001). Considering conventional indexes of RV function, only Sm and dp/dt were 
      significantly better in the first group compared with the second group (p-value 
      for Sm = 0.042 and for dp/dt = 0.039). RV end diastolic dimension was 
      significantly higher in the IPH group (p = 0.013). Using deformation indexes of 
      RV function, the basal and mid portion of RV free wall strain and basal RV strain 
      rates were significantly worse in the chronic systolic heart failure (PH-HF) 
      group in comparison to the IPH group (p < 0.001 in basal RV strain, p = 0.034 in 
      mid RV strain and p = 0.046 in basal RV strain rate respectively). CONCLUSION: 
      IPH has less impact on RV function in comparison to PH-HF. Considering both 
      entities are in the category of RV pressure overload, we conclude that the 
      etiology of pulmonary hypertension also plays an important role in RV function in 
      addition to pressure overload.
FAU - Emami, Sepideh
AU  - Emami S
AD  - Firoozgar Clinical Research and Development Center, Iran University of Medical 
      Sciences, Tehran, Iran.
FAU - Samiei, Niloufar
AU  - Samiei N
AD  - Echocardiography Research Center, Rajaei Cardiovascular, Medical and Research 
      Center, Iran University of Medical Sciences, Tehran, Iran.
FAU - Amin, Ahamd
AU  - Amin A
AD  - Department of Heart Failure, Rajaei Cardiovascular, Medical and Research Center, 
      Iran University of Medical Sciences, Tehran, Iran.
FAU - Taghavi, Sepideh
AU  - Taghavi S
AD  - Department of Heart Failure, Rajaei Cardiovascular, Medical and Research Center, 
      Iran University of Medical Sciences, Tehran, Iran.
FAU - Parsaee, Mozhghan
AU  - Parsaee M
AD  - Echocardiography Research Center, Rajaei Cardiovascular, Medical and Research 
      Center, Iran University of Medical Sciences, Tehran, Iran.
FAU - Naderi, Nasim
AU  - Naderi N
AD  - Department of Heart Failure, Rajaei Cardiovascular, Medical and Research Center, 
      Iran University of Medical Sciences, Tehran, Iran.
FAU - Serati, Alireza
AU  - Serati A
AD  - Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, 
      Tehran, Iran.
FAU - Movahed, Mohammad Reza
AU  - Movahed MR
AD  - Department of Medicine, University of Arizona, Tucson, Arizona. rmova@aol.com.
AD  - Department of Medicine, University of Arizona, Phoenix, Arizona. rmova@aol.com.
AD  - CareMore Regional Cardiology Director, Tucson, Arizona. rmova@aol.com.
LA  - eng
PT  - Journal Article
PL  - Switzerland
TA  - Adv Respir Med
JT  - Advances in respiratory medicine
JID - 101697329
SB  - IM
MH  - Adult
MH  - Case-Control Studies
MH  - Echocardiography, Doppler
MH  - Familial Primary Pulmonary Hypertension/*diagnostic imaging/physiopathology
MH  - Female
MH  - Humans
MH  - Hypertension, Pulmonary/*diagnostic imaging/physiopathology
MH  - Male
MH  - Middle Aged
MH  - Ventricular Dysfunction, Right/*diagnostic imaging/physiopathology
MH  - Ventricular Function, Right
OTO - NOTNLM
OT  - Doppler echocardiography
OT  - myocardial strain
OT  - pulmonary artery hypertension
OT  - pulmonary hypertension
OT  - right ventricular function
EDAT- 2020/03/11 06:00
MHDA- 2021/01/14 06:00
CRDT- 2020/03/11 06:00
PHST- 2019/06/10 00:00 [received]
PHST- 2019/12/15 00:00 [accepted]
PHST- 2019/12/12 00:00 [revised]
PHST- 2020/03/11 06:00 [entrez]
PHST- 2020/03/11 06:00 [pubmed]
PHST- 2021/01/14 06:00 [medline]
AID - VM/OJS/J/64648 [pii]
AID - 10.5603/ARM.2020.0071 [doi]
PST - ppublish
SO  - Adv Respir Med. 2020;88(1):1-5. doi: 10.5603/ARM.2020.0071.