PMID- 32158185
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220413
IS  - 1177-5467 (Print)
IS  - 1177-5483 (Electronic)
IS  - 1177-5467 (Linking)
VI  - 14
DP  - 2020
TI  - 532-nm Subthreshold Micropulse Laser for the Treatment of Chronic Central Serous 
      Retinopathy.
PG  - 525-531
LID - 10.2147/OPTH.S232202 [doi]
AB  - INTRODUCTION: Subthreshold micropulse laser treatment with a 532 nm (532-SML) 
      wavelength has been suggested as a treatment option for the treatment of chronic 
      central serous retinopathy (cCSR). The objective is to present its effects and 
      complications. METHODS: We present a retrospective cohort study of cCSR patients 
      submitted to 532-SML. Best-corrected visual acuity (BCVA) and spectral-domain 
      optical coherence tomography (SD-OCT) parameters - central macular thickness, 
      subfoveal outer nuclear layer, external limiting membrane, ellipsoid band, 
      interdigitation band, subretinal fluid and choroidal thickness - were evaluated 
      before and 12 weeks after treatment. A power of 50%, a duty cycle of 5%, exposure 
      time of 200 ms and a spot size of 160 microm were the applied laser parameters. 
      RESULTS: We included 26 eyes. Overall there were no significant changes in visual 
      acuity (median 0.20 (IQR 0) logMAR before and after treatment) or SD-OCT 
      parameters. However, visual benefits occurred in 42.3% (n=11) of the patients and 
      in half of the cases, subretinal fluid was completely reabsorbed. There were no 
      complications. CONCLUSION: In this study, 532-SML was overall ineffective on cCSR 
      as it did not lead to significant changes in the overall median visual acuity and 
      SD-OCT parameters. However, some patients may have benefited functionally and 
      anatomically from the treatment; further investigation is necessary to understand 
      the potential of 532-SML.
CI  - (c) 2020 Sousa et al.
FAU - Sousa, Keissy
AU  - Sousa K
AUID- ORCID: 0000-0002-8209-6901
AD  - Retina Department of Hospital de Braga, Braga, Portugal.
FAU - Calvao-Santos, Gil
AU  - Calvao-Santos G
AD  - Retina Department of Hospital de Braga, Braga, Portugal.
FAU - Joao, Marina
AU  - Joao M
AD  - Ophthalmology Department of Hospital de Braga, Braga, Portugal.
FAU - Gomes, Nuno
AU  - Gomes N
AD  - Retina Department of Hospital de Braga, Braga, Portugal.
FAU - Falcao, Manuel
AU  - Falcao M
AUID- ORCID: 0000-0003-4718-0910
AD  - Retina Department of Centro Hospitalar Universitario S. Joao, Porto, Portugal.
AD  - Department of Surgery and Physiology of Faculty of Medicine of the University of 
      Porto, Porto, Portugal.
LA  - eng
PT  - Journal Article
DEP - 20200225
PL  - New Zealand
TA  - Clin Ophthalmol
JT  - Clinical ophthalmology (Auckland, N.Z.)
JID - 101321512
PMC - PMC7049285
OTO - NOTNLM
OT  - 532 nm wavelength
OT  - SD-OCT
OT  - central serous retinopathy
OT  - outer retina bands
OT  - subthreshold micropulse laser
COIS- The authors report no conflicts of interest in this work.
EDAT- 2020/03/12 06:00
MHDA- 2020/03/12 06:01
PMCR- 2020/02/25
CRDT- 2020/03/12 06:00
PHST- 2019/09/23 00:00 [received]
PHST- 2020/01/08 00:00 [accepted]
PHST- 2020/03/12 06:00 [entrez]
PHST- 2020/03/12 06:00 [pubmed]
PHST- 2020/03/12 06:01 [medline]
PHST- 2020/02/25 00:00 [pmc-release]
AID - 232202 [pii]
AID - 10.2147/OPTH.S232202 [doi]
PST - epublish
SO  - Clin Ophthalmol. 2020 Feb 25;14:525-531. doi: 10.2147/OPTH.S232202. eCollection 
      2020.