PMID- 32164109 OWN - NLM STAT- MEDLINE DCOM- 20200428 LR - 20200428 IS - 0376-2491 (Print) IS - 0376-2491 (Linking) VI - 100 IP - 7 DP - 2020 Feb 25 TI - [Five million wear simulation and particle analysis of carbon-based nano-multilayer coatings titanium alloy femoral head]. PG - 546-551 LID - 10.3760/cma.j.issn.0376-2491.2020.07.014 [doi] AB - Objective: To analyze the wear debris characteristics ofcarbon-based nano- multilayer coatings on Ti(6)Al(4)V alloys and compared with the cobalt chromium molybdenum alloy (CoCrMo) femoral head to evaluate the friction and wear performance of the new coated femoral head. Methods: Three groups were set up in the wear simulation experiment according to the type of femoral head. Group A: imported Cobalt-Chromium-Molybdenum alloy femoral head (CoCrMo); group B: Titanium alloy femoral head (Ti(6)Al(4)V) with carbon-based nano-multilayer coatings; group C: domestic Cobalt-Chromium-Molybdenum alloy femoral head (CoCrMo). All heads were jointed with an ultra-high molecular weight polyethylene (UHMWPE) acetabular cup. Serum samples were collected and stored in the hip joint simulator. After the sample has been digested and diluted, it was filtered through 5 mum, 1.2 mum and 0.4 mum filters, and the filter paper was collected for testing. Scanning electron microscope (SEM) was used to randomly select regions on the filter to obtain images of wear debris. Energy dispersive X-ray spectroscopy (EDS) was used to determine the elemental type of the particle and to eliminate possible contamination. The composition and structure of the abrasive chips were measured using Fourier transform infrared spectrometer (FTIR). The parameters related to the wear debris includingparticle size, shape, number and volume were calculated. The differences in correlation parameters between the groups were compared to evaluate the friction and wear properties of the new coated joints. Results: The main component of the wear debris produced was UHMWPE, and the particle size was mostly below 1 mum. The submicron particle ratio of group B was 49.4%, which was significantly lower than that of the group A and C (75% and 60%, respectively; chi(2)=66.032, 31.754, both P<0.017). The shape was mainly round, and there was no statistical difference between the groups (chi(2)=0.590, P=0.744). The number of particles in group B was significantly less than that of group C on all filters (t=9.960, 8.019, 5.790, all P<0.01), and less than group A on the 0.4 mum filter (t=7.810, P=0.000). Conclusion: The frictional wear performance of the new carbon-based nano-multilayer coatings femoral head is significantly better than that of the domestic femoral head, and even partially exceeds the imported femoral head level, which helps to reduce the production of particles and prevent osteolysis and aseptic loosening induced by UHMWPE particles. FAU - Wang, H R AU - Wang HR AD - Department of Orthopedics, People's Liberation Army General Hospital, Beijing 100853, China. FAU - Li, J AU - Li J AD - Department of Orthopedics, People's Liberation Army General Hospital, Beijing 100853, China. FAU - Li, Z L AU - Li ZL AD - Department of Orthopedics, People's Liberation Army General Hospital, Beijing 100853, China. FAU - Tu, J P AU - Tu JP AD - School of Materials Science and Engineering, Zhejiang University, Hangzhou 310027, China. FAU - Jin, G AU - Jin G AD - Zhongaohuicheng Technology Co., Beijing 100176, China. FAU - Su, J AU - Su J AD - Beijing Institute of Medical Instruments, Beijing 101111, China. FAU - Wang, J J AU - Wang JJ AD - Beijing Institute of Medical Instruments, Beijing 101111, China. LA - chi GR - 2016YFC1101905/National Key Research and Development Program/ PT - Journal Article PL - China TA - Zhonghua Yi Xue Za Zhi JT - Zhonghua yi xue za zhi JID - 7511141 RN - 0 (Alloys) RN - 7440-44-0 (Carbon) RN - D1JT611TNE (Titanium) SB - IM MH - Alloys MH - Carbon MH - *Femur Head MH - *Hip Prosthesis MH - Humans MH - Materials Testing MH - Prosthesis Failure MH - Titanium OTO - NOTNLM OT - Particle analysis OT - Total hip arthroplasty OT - Ultra high molecular weight polyethylene OT - Wear EDAT- 2020/03/14 06:00 MHDA- 2020/04/29 06:00 CRDT- 2020/03/13 06:00 PHST- 2020/03/13 06:00 [entrez] PHST- 2020/03/14 06:00 [pubmed] PHST- 2020/04/29 06:00 [medline] AID - 10.3760/cma.j.issn.0376-2491.2020.07.014 [doi] PST - ppublish SO - Zhonghua Yi Xue Za Zhi. 2020 Feb 25;100(7):546-551. doi: 10.3760/cma.j.issn.0376-2491.2020.07.014.