PMID- 32165840
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220413
IS  - 1117-6806 (Print)
IS  - 2278-7100 (Electronic)
IS  - 1117-6806 (Linking)
VI  - 26
IP  - 1
DP  - 2020 Jan-Jun
TI  - Factors Determining Diabetic Remission after Sleeve Gastrectomy: A Prospective 
      Study.
PG  - 66-71
LID - 10.4103/njs.NJS_9_19 [doi]
AB  - BACKGROUND: An exponential rise in the prevalence of obesity and the associated 
      type 2 diabetes mellitus (T2DM) has led to an explosion in the field of bariatric 
      surgery worldwide. It has been proposed that laparoscopic sleeve gastrectomy 
      (LSG) not only results in excess weight loss (EWL) but also leads to excellent 
      glycemic control. AIMS: However, not every patient benefits from the bariatric 
      surgery. Furthermore, bariatric surgery is currently indicated based on body mass 
      index (BMI), but BMI solely does not predict diabetes remission after the 
      surgery. We aimed to study the outcome of LSG on the diabetic status and the 
      factors predicting the disease remission. SUBJECTS AND METHODS: This prospective 
      study was conducted on 104 obese patients having T2DM who underwent LSG. 
      Following surgery, the clinical outcome on weight loss, BMI, and glycemic control 
      was studied for 6 months. Various positive and negative predictors of diabetic 
      remission after the surgery were also determined. Student's t-test and Chi-square 
      tests were applied. RESULTS: LSG resulted in significant weight loss (P < 0.05); 
      the percentage of EWL was 60.75 +/- 6.30 at 6 months. Furthermore, surgery resulted 
      in 78.9% remission of diabetes with fasting blood glucose and glycated hemoglobin 
      values at 6 months being 121.13 +/- 15.25 mg/dl and 6.19% +/- 0.31%, respectively. 
      Younger and heavier patients, those with lesser disease severity and shorter 
      duration had better chances of disease remission. Gender had no correlation with 
      disease remission. CONCLUSION: LSG is a successful treatment option for T2DM and 
      is more beneficial if offered, not as a last option, but to younger, obese 
      patients with mild disease severity and shorter disease duration after the 
      failure of medical treatment.
CI  - Copyright: (c) 2020 Nigerian Journal of Surgery.
FAU - Jindal, Rohit
AU  - Jindal R
AD  - Department of General Surgery, Dayanand Medical College and Hospital, Ludhiana, 
      Punjab, India.
FAU - Gupta, Mayank
AU  - Gupta M
AD  - Department of General Surgery, Dayanand Medical College and Hospital, Ludhiana, 
      Punjab, India.
FAU - Ahuja, Ashish
AU  - Ahuja A
AD  - Department of General Surgery, Dayanand Medical College and Hospital, Ludhiana, 
      Punjab, India.
FAU - Nain, Prabhdeep Singh
AU  - Nain PS
AD  - Department of General Surgery, Dayanand Medical College and Hospital, Ludhiana, 
      Punjab, India.
FAU - Sharma, Pranjl
AU  - Sharma P
AD  - Department of Community Medicine, Dayanand Medical College and Hospital, 
      Ludhiana, Punjab, India.
FAU - Aggarwal, Aayushi
AU  - Aggarwal A
AD  - Department of General Surgery, Dayanand Medical College and Hospital, Ludhiana, 
      Punjab, India.
LA  - eng
PT  - Journal Article
DEP - 20200210
PL  - India
TA  - Niger J Surg
JT  - Nigerian journal of surgery : official publication of the Nigerian Surgical 
      Research Society
JID - 101189891
PMC - PMC7041342
OTO - NOTNLM
OT  - Bariatric surgery
OT  - diabetes remission
OT  - laparoscopic sleeve gastrectomy
OT  - predictor
OT  - type 2 diabetes mellitus
COIS- There are no conflicts of interest.
EDAT- 2020/03/14 06:00
MHDA- 2020/03/14 06:01
PMCR- 2020/01/01
CRDT- 2020/03/14 06:00
PHST- 2019/03/01 00:00 [received]
PHST- 2019/07/08 00:00 [revised]
PHST- 2019/09/19 00:00 [accepted]
PHST- 2020/03/14 06:00 [entrez]
PHST- 2020/03/14 06:00 [pubmed]
PHST- 2020/03/14 06:01 [medline]
PHST- 2020/01/01 00:00 [pmc-release]
AID - NJS-26-66 [pii]
AID - 10.4103/njs.NJS_9_19 [doi]
PST - ppublish
SO  - Niger J Surg. 2020 Jan-Jun;26(1):66-71. doi: 10.4103/njs.NJS_9_19. Epub 2020 Feb 
      10.