PMID- 32170427 OWN - NLM STAT- MEDLINE DCOM- 20201030 LR - 20201030 IS - 1436-2813 (Electronic) IS - 0941-1291 (Linking) VI - 50 IP - 9 DP - 2020 Sep TI - Prognostic factors and a new preliminary scoring system for remission of type 2 diabetes mellitus after laparoscopic sleeve gastrectomy. PG - 1056-1064 LID - 10.1007/s00595-020-01990-z [doi] AB - PURPOSE: To evaluate the early remission rate of type 2 diabetes mellitus (T2DM) after laparoscopic sleeve gastrectomy (LSG) and establish a preliminary scoring system that predicts T2DM remission. METHODS: We assessed the outcomes of 49 morbidly obese patients with T2DM who underwent LSG between 2008 and 2018. The prognostic factors for T2DM remission 1 year post-LSG were identified and an original scoring system was established. We validated our scoring system by comparing it with the individualized metabolic surgery score and the ABCD score. RESULTS: The patients' mean body weight loss and percentage of excess weight loss were 34.4 kg and 59.4%, respectively, while the T2DM remission rate was 77.5%. The serum insulin level and the T2DM duration were independent predictive factors, the receiver-operating characteristic (ROC) curves for which revealed cutoff values of 12.7 ng/mL and 72 months, respectively. We set our system's score range at 0-2, whereby patients with higher scores have a good T2DM remission prognosis, as higher insulin levels, and/or shorter T2DM duration. Our scoring system had accuracy levels similar to those of the ABCD score with a simple stratification. CONCLUSION: Our preliminary scoring system attains a good level of accuracy for predicting T2DM remission. FAU - Umemura, Akira AU - Umemura A AD - Department of Surgery, Iwate Medical University, 19-1 Uchimaru, Morioka, Iwate, 020-8505, Japan. aumemura@iwate-med.ac.jp. FAU - Sasaki, Akira AU - Sasaki A AD - Department of Surgery, Iwate Medical University, 19-1 Uchimaru, Morioka, Iwate, 020-8505, Japan. FAU - Nitta, Hiroyuki AU - Nitta H AD - Department of Surgery, Iwate Medical University, 19-1 Uchimaru, Morioka, Iwate, 020-8505, Japan. FAU - Nikai, Haruka AU - Nikai H AD - Department of Surgery, Iwate Medical University, 19-1 Uchimaru, Morioka, Iwate, 020-8505, Japan. FAU - Baba, Shigeaki AU - Baba S AD - Department of Surgery, Iwate Medical University, 19-1 Uchimaru, Morioka, Iwate, 020-8505, Japan. FAU - Takahara, Takeshi AU - Takahara T AD - Department of Surgery, Iwate Medical University, 19-1 Uchimaru, Morioka, Iwate, 020-8505, Japan. FAU - Hasegawa, Yasushi AU - Hasegawa Y AD - Department of Surgery, Iwate Medical University, 19-1 Uchimaru, Morioka, Iwate, 020-8505, Japan. FAU - Katagiri, Hirokatsu AU - Katagiri H AD - Department of Surgery, Iwate Medical University, 19-1 Uchimaru, Morioka, Iwate, 020-8505, Japan. FAU - Kanno, Shoji AU - Kanno S AD - Department of Surgery, Iwate Medical University, 19-1 Uchimaru, Morioka, Iwate, 020-8505, Japan. FAU - Ishigaki, Yasushi AU - Ishigaki Y AD - Division of Diabetes and Metabolism, Department of Internal Medicine, Iwate Medical University, Morioka, Iwate, 020-8505, Japan. LA - eng PT - Journal Article DEP - 20200313 PL - Japan TA - Surg Today JT - Surgery today JID - 9204360 SB - IM MH - Adolescent MH - Adult MH - Aged MH - Bariatric Surgery/*methods MH - Diabetes Mellitus, Type 2/complications/*surgery MH - Endoscopy, Gastrointestinal/*methods MH - Female MH - Gastrectomy/*methods MH - Humans MH - Laparoscopy/*methods MH - Male MH - Middle Aged MH - Obesity, Morbid/complications/*surgery MH - Prognosis MH - Remission Induction MH - *Research Design MH - Retrospective Studies MH - Young Adult OTO - NOTNLM OT - Bariatric surgery OT - Complete remission OT - Diabetes mellitus OT - Laparoscopic sleeve gastrectomy OT - Metabolic surgery EDAT- 2020/03/15 06:00 MHDA- 2020/10/31 06:00 CRDT- 2020/03/15 06:00 PHST- 2019/12/18 00:00 [received] PHST- 2020/02/11 00:00 [accepted] PHST- 2020/03/15 06:00 [pubmed] PHST- 2020/10/31 06:00 [medline] PHST- 2020/03/15 06:00 [entrez] AID - 10.1007/s00595-020-01990-z [pii] AID - 10.1007/s00595-020-01990-z [doi] PST - ppublish SO - Surg Today. 2020 Sep;50(9):1056-1064. doi: 10.1007/s00595-020-01990-z. Epub 2020 Mar 13.