PMID- 32180436
OWN - NLM
STAT- MEDLINE
DCOM- 20200622
LR  - 20221207
IS  - 1940-1574 (Electronic)
IS  - 0003-3197 (Linking)
VI  - 71
IP  - 6
DP  - 2020 Jul
TI  - Morphological Carotid Plaque Area Is Associated With Glomerular Filtration Rate: 
      A Study of South Asian Indian Patients With Diabetes and Chronic Kidney Disease.
PG  - 520-535
LID - 10.1177/0003319720910660 [doi]
AB  - We evaluated the association between automatically measured carotid total plaque 
      area (TPA) and the estimated glomerular filtration rate (eGFR), a biomarker of 
      chronic kidney disease (CKD). Automated average carotid intima-media thickness 
      (cIMTave) and TPA measurements in carotid ultrasound (CUS) were performed using 
      AtheroEdge (AtheroPoint). Pearson correlation coefficient (CC) was then computed 
      between the TPA and eGFR for (1) males versus females, (2) diabetic versus 
      nondiabetic patients, and (3) between the left and right carotid artery. Overall, 
      339 South Asian Indian patients with either type 2 diabetes mellitus (T2DM) or 
      CKD, or hypertension (stage 1 or stage 2) were retrospectively analyzed by 
      acquiring cIMTave and TPA measurements of their left and right common carotid 
      arteries (CCA; total CUS: 678, mean age: 54.2 +/- 9.8 years; 75.2% males; 93.5% 
      with T2DM). The CC between TPA and eGFR for different scenarios were (1) for 
      males and females -0.25 (P < .001) and -0.35 (P < .001), respectively; (2) for 
      T2DM and non-T2DM -0.26 (P < .001) and -0.49 (P = .02), respectively, and (3) for 
      left and right CCA -0.25 (P < .001) and -0.23 (P < .001), respectively. Automated 
      TPA is an equally reliable biomarker compared with cIMTave for patients with CKD 
      (with or without T2DM) with subclinical atherosclerosis.
FAU - Puvvula, Anudeep
AU  - Puvvula A
AD  - Annu's Hospitals for Skin and Diabetes, Nellore, Andhra Pradesh, India.
FAU - Jamthikar, Ankush D
AU  - Jamthikar AD
AD  - Department of Electronics and Communications Engineering, Visvesvaraya National 
      Institute of Technology, Nagpur, Maharashtra, India.
FAU - Gupta, Deep
AU  - Gupta D
AD  - Department of Electronics and Communications Engineering, Visvesvaraya National 
      Institute of Technology, Nagpur, Maharashtra, India.
FAU - Khanna, Narendra N
AU  - Khanna NN
AD  - Department of Cardiology, Indraprastha Apollo Hospitals, New Delhi, Delhi, India.
FAU - Porcu, Michele
AU  - Porcu M
AUID- ORCID: 0000-0002-3090-8541
AD  - Department of Radiology, Azienda Ospedaliero Universitaria (A.O.U.), Cagliari, 
      Italy.
FAU - Saba, Luca
AU  - Saba L
AD  - Department of Radiology, Azienda Ospedaliero Universitaria (A.O.U.), Cagliari, 
      Italy.
FAU - Viskovic, Klaudija
AU  - Viskovic K
AD  - Department of Radiology and Ultrasound, University Hospital for Infectious 
      Diseases, Zagreb, Croatia.
FAU - Ajuluchukwu, Janet N A
AU  - Ajuluchukwu JNA
AD  - Department of Medicine, LUTH (Lagos University Teaching Hospital), Lagos, 
      Nigeria.
FAU - Gupta, Ajay
AU  - Gupta A
AD  - Department of Radiology, Weill Cornell Medicine, New York City, NY, USA.
FAU - Mavrogeni, Sophie
AU  - Mavrogeni S
AD  - Cardiology Clinic, Onassis Cardiac Surgery Center, Athens, Greece.
FAU - Turk, Monika
AU  - Turk M
AD  - Department of Neurology, University Medical Centre Maribor, Slovenia.
FAU - Laird, John R
AU  - Laird JR
AD  - Heart and Vascular Institute, Adventist Health St Helena, St Helena, CA, USA.
FAU - Pareek, Gyan
AU  - Pareek G
AD  - Minimally Invasive Urology Institute, Brown University, Providence, RI, USA.
FAU - Miner, Martin
AU  - Miner M
AD  - Men's Health Center, Miriam Hospital, Providence, RI, USA.
FAU - Sfikakis, Petros P
AU  - Sfikakis PP
AD  - Rheumatology Unit, National Kapodistrian University of Athens, Greece.
FAU - Protogerou, Athanasios
AU  - Protogerou A
AD  - Department of Cardiovascular Prevention and Research Unit Clinic and Laboratory 
      of Pathophysiology, National and Kapodistrian University of Athens, Greece.
FAU - Kitas, George D
AU  - Kitas GD
AD  - R & D Academic Affairs, Dudley Group NHS Foundation Trust, Dudley, United 
      Kingdom.
FAU - Nicolaides, Andrew
AU  - Nicolaides A
AD  - Vascular Screening and Diagnostic Centre and University of Nicosia Medical 
      School, Cyprus.
FAU - Viswanathan, Vijay
AU  - Viswanathan V
AD  - M. V. Hospital for Diabetes and Professor M. Viswanathan Diabetes Research 
      Centre, Chennai, Tamil Nadu, India.
FAU - Suri, Jasjit S
AU  - Suri JS
AUID- ORCID: 0000-0001-6499-396X
AD  - Stroke Monitoring and Diagnostic Division, AtheroPoint, Roseville, CA, USA.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20200317
PL  - United States
TA  - Angiology
JT  - Angiology
JID - 0203706
SB  - IM
CIN - Angiology. 2020 Jul;71(6):489-490. PMID: 32252536
MH  - Adult
MH  - Aged
MH  - Asian People
MH  - Blood Pressure
MH  - Carotid Artery Diseases/*diagnostic imaging/ethnology
MH  - Carotid Artery, Common/*diagnostic imaging
MH  - *Carotid Intima-Media Thickness
MH  - Cross-Sectional Studies
MH  - *Diabetes Mellitus, Type 2/diagnosis/ethnology
MH  - Female
MH  - *Glomerular Filtration Rate
MH  - Humans
MH  - Hypertension/ethnology/physiopathology
MH  - India/epidemiology
MH  - Kidney/*physiopathology
MH  - Male
MH  - Middle Aged
MH  - *Plaque, Atherosclerotic
MH  - Predictive Value of Tests
MH  - Renal Insufficiency, Chronic/diagnosis/ethnology/*physiopathology
MH  - Retrospective Studies
MH  - Risk Assessment
MH  - Risk Factors
OTO - NOTNLM
OT  - atherosclerosis
OT  - cardiovascular disease
OT  - carotid intima-media thickness
OT  - chronic kidney disease
OT  - estimated glomerular filtration rate
OT  - morphological total plaque area
OT  - risk assessment
EDAT- 2020/03/18 06:00
MHDA- 2020/06/23 06:00
CRDT- 2020/03/18 06:00
PHST- 2020/03/18 06:00 [pubmed]
PHST- 2020/06/23 06:00 [medline]
PHST- 2020/03/18 06:00 [entrez]
AID - 10.1177/0003319720910660 [doi]
PST - ppublish
SO  - Angiology. 2020 Jul;71(6):520-535. doi: 10.1177/0003319720910660. Epub 2020 Mar 
      17.