PMID- 32181345
OWN - NLM
STAT- MEDLINE
DCOM- 20201112
LR  - 20240328
IS  - 2375-2548 (Electronic)
IS  - 2375-2548 (Linking)
VI  - 6
IP  - 10
DP  - 2020 Mar
TI  - Human transport of thirdhand tobacco smoke: A prominent source of hazardous air 
      pollutants into indoor nonsmoking environments.
PG  - eaay4109
LID - 10.1126/sciadv.aay4109 [doi]
LID - eaay4109
AB  - The contamination of indoor nonsmoking environments with thirdhand smoke (THS) is 
      an important, poorly understood public health concern. Real-time THS off-gassing 
      from smokers into a nonsmoking movie theater was observed with online and offline 
      high-resolution mass spectrometry. Prominent emission events of THS tracers 
      (e.g., 2,5-dimethylfuran, 2-methylfuran, and acetonitrile) and other 
      tobacco-related volatile organic compounds (VOCs) coincided with the arrival of 
      certain moviegoers and left residual contamination. These VOC emission events 
      exposed occupants to the equivalent of 1 to 10 cigarettes of secondhand smoke, 
      including multiple hazardous air pollutants (e.g., benzene and formaldehyde) at 
      parts-per-billion concentrations. Nicotine and related intermediate-volatility 
      nitrogen-containing compounds, which vaporized from clothes/bodies and 
      recondensed onto aerosol, comprised 34% of observed functionalized organic 
      aerosol abundance. Exposure to THS VOC emission events will be considerably 
      enhanced in poorly ventilated or smaller spaces in contrast with a large, 
      well-ventilated theater-amplifying concentrations and potential impacts on health 
      and indoor chemistry.
CI  - Copyright (c) 2020 The Authors, some rights reserved; exclusive licensee American 
      Association for the Advancement of Science. No claim to original U.S. Government 
      Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 
      (CC BY-NC).
FAU - Sheu, Roger
AU  - Sheu R
AUID- ORCID: 0000-0001-7342-3790
AD  - Department of Chemical and Environmental Engineering, Yale University, New Haven, 
      CT, USA.
FAU - Stonner, Christof
AU  - Stonner C
AUID- ORCID: 0000-0002-5560-0842
AD  - Max Planck Institute for Chemistry, Mainz 55128, Germany.
FAU - Ditto, Jenna C
AU  - Ditto JC
AUID- ORCID: 0000-0001-6531-4412
AD  - Department of Chemical and Environmental Engineering, Yale University, New Haven, 
      CT, USA.
FAU - Klupfel, Thomas
AU  - Klupfel T
AD  - Max Planck Institute for Chemistry, Mainz 55128, Germany.
FAU - Williams, Jonathan
AU  - Williams J
AUID- ORCID: 0000-0001-9421-1703
AD  - Max Planck Institute for Chemistry, Mainz 55128, Germany.
FAU - Gentner, Drew R
AU  - Gentner DR
AUID- ORCID: 0000-0003-3066-2614
AD  - Department of Chemical and Environmental Engineering, Yale University, New Haven, 
      CT, USA.
AD  - Max Planck Institute for Chemistry, Mainz 55128, Germany.
AD  - SEARCH (Solutions for Energy, Air, Climate and Health) Center, Yale University, 
      New Haven, CT, USA.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20200304
PL  - United States
TA  - Sci Adv
JT  - Science advances
JID - 101653440
RN  - 0 (Acetonitriles)
RN  - 0 (Aerosols)
RN  - 0 (Furans)
RN  - 0 (Tobacco Smoke Pollution)
RN  - 0 (Volatile Organic Compounds)
RN  - 1HG84L3525 (Formaldehyde)
RN  - 51O3BGW3F2 (2-methylfuran)
RN  - 6M3C89ZY6R (Nicotine)
RN  - DR5HL9OJ7Y (2,5-dimethylfuran)
RN  - J64922108F (Benzene)
RN  - Z072SB282N (acetonitrile)
SB  - IM
MH  - Acetonitriles/analysis/chemistry
MH  - Aerosols
MH  - Air Pollution, Indoor/*analysis
MH  - Benzene/*analysis/chemistry
MH  - Formaldehyde/analysis/chemistry
MH  - Furans/*analysis/chemistry
MH  - Germany
MH  - Humans
MH  - Mass Spectrometry
MH  - Motion Pictures
MH  - Nicotine/*analysis/chemistry
MH  - Tobacco Smoke Pollution/*analysis
MH  - Volatile Organic Compounds/*analysis/classification
PMC - PMC7056301
EDAT- 2020/03/18 06:00
MHDA- 2020/11/13 06:00
PMCR- 2020/03/04
CRDT- 2020/03/18 06:00
PHST- 2019/08/22 00:00 [received]
PHST- 2019/12/10 00:00 [accepted]
PHST- 2020/03/18 06:00 [entrez]
PHST- 2020/03/18 06:00 [pubmed]
PHST- 2020/11/13 06:00 [medline]
PHST- 2020/03/04 00:00 [pmc-release]
AID - aay4109 [pii]
AID - 10.1126/sciadv.aay4109 [doi]
PST - epublish
SO  - Sci Adv. 2020 Mar 4;6(10):eaay4109. doi: 10.1126/sciadv.aay4109. eCollection 2020 
      Mar.