PMID- 32182905
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200928
IS  - 2076-3921 (Print)
IS  - 2076-3921 (Electronic)
IS  - 2076-3921 (Linking)
VI  - 9
IP  - 3
DP  - 2020 Mar 9
TI  - Oxidative Status of Goats with Different CSN1S1 Genotypes Fed ad Libitum with 
      Fresh and Dry Forages.
LID - 10.3390/antiox9030224 [doi]
LID - 224
AB  - Forty late-lactation Girgentana goats were used to study the effect of diets fed 
      ad libitum and alphaS1-casein (CSN1S1) genotype on redox balance. The goats genotyped 
      at CSN1S1 locus (A/A, A/F) were subjected to four feeding treatments different 
      for percentage inclusion of dry and fresh forage: DAF100 (98% of Dry Alfalfa 
      Forage), DAF65 (65% of Dry Alfalfa Forage), FSF100 (100% of Fresh Sulla Forage) 
      and FSF65 (65% of Fresh Sulla Forage). Blood samples were analyzed for superoxide 
      dismutase (SOD) and glutathione peroxidase (GPX) activity, reactive oxygen 
      metabolites (ROMs), biological antioxidant potential (BAP) and non-esterified 
      fatty acids (NEFA), beta-hydroxybutyrate (BHBA), albumin, glucose and cholesterol 
      contents. The oxidative stress index (OSI) was calculated as percentage ratio of 
      ROMs to BAP. Redox balance was improved by Sulla inclusion, as reflected in the 
      lower OSI values found in FSF100 and FSF65 groups. DAF100 group displayed the 
      highest GPX activity, while other groups exhibited the highest SOD activity. 
      Fresh forage diets increased albumin concentration while no effect of tested 
      factors was noted on glucose, NEFA, BHBA and cholesterol contents. The 
      interaction diet x genotype was significant only for GPX activity. GPX and 
      albumin were negatively correlated and were correlated positively and negatively 
      with ROMs, respectively. Diet rather than genotype affects redox balance in dairy 
      goats and a possible role of forage polyphenol compounds on oxidative status 
      needs to be tested in future studies.
FAU - Giorgio, Daniela
AU  - Giorgio D
AD  - Scuola di Scienze Agrarie, Forestali, Alimentari e Ambientali (SAFE), University 
      of Basilicata, Viale dell'Ateneo Lucano, 10, 85100 Potenza, Italy.
FAU - Di Trana, Adriana
AU  - Di Trana A
AD  - Scuola di Scienze Agrarie, Forestali, Alimentari e Ambientali (SAFE), University 
      of Basilicata, Viale dell'Ateneo Lucano, 10, 85100 Potenza, Italy.
FAU - Di Gregorio, Paola
AU  - Di Gregorio P
AD  - Scuola di Scienze Agrarie, Forestali, Alimentari e Ambientali (SAFE), University 
      of Basilicata, Viale dell'Ateneo Lucano, 10, 85100 Potenza, Italy.
FAU - Rando, Andrea
AU  - Rando A
AD  - Scuola di Scienze Agrarie, Forestali, Alimentari e Ambientali (SAFE), University 
      of Basilicata, Viale dell'Ateneo Lucano, 10, 85100 Potenza, Italy.
FAU - Avondo, Marcella
AU  - Avondo M
AD  - Dipartimento di Agricoltura, Alimentazione e Ambiente (Di3A), University of 
      Catania, Via Valdisavoia 5, 95123 Catania, Italy.
FAU - Bonanno, Adriana
AU  - Bonanno A
AD  - Dipartimento Scienze Agrarie, Alimentari e Forestali, Universita degli Studi di 
      Palermo, Viale delle Scienze, 90128 Palermo, Italy.
FAU - Valenti, Bernardo
AU  - Valenti B
AD  - Dipartimento di Scienze Agrarie, Alimentari e Ambientali, University of Perugia, 
      Borgo XX Giugno 74, 06121 Perugia, Italy.
FAU - Grigoli, Antonino Di
AU  - Grigoli AD
AD  - Dipartimento Scienze Agrarie, Alimentari e Forestali, Universita degli Studi di 
      Palermo, Viale delle Scienze, 90128 Palermo, Italy.
LA  - eng
GR  - 2007B4JBWN003/Ministero dell'Istruzione, dell'Universita e della Ricerca/
GR  - 102050101/17/Universita degli Studi della Basilicata/
PT  - Journal Article
DEP - 20200309
PL  - Switzerland
TA  - Antioxidants (Basel)
JT  - Antioxidants (Basel, Switzerland)
JID - 101668981
PMC - PMC7139644
OTO - NOTNLM
OT  - CSN1S1 genotype
OT  - diet
OT  - enzymatic antioxidants
OT  - fresh forage
OT  - goat
OT  - redox balance
COIS- The authors declare no conflict of interest.
EDAT- 2020/03/19 06:00
MHDA- 2020/03/19 06:01
PMCR- 2020/03/09
CRDT- 2020/03/19 06:00
PHST- 2020/02/06 00:00 [received]
PHST- 2020/03/02 00:00 [revised]
PHST- 2020/03/05 00:00 [accepted]
PHST- 2020/03/19 06:00 [entrez]
PHST- 2020/03/19 06:00 [pubmed]
PHST- 2020/03/19 06:01 [medline]
PHST- 2020/03/09 00:00 [pmc-release]
AID - antiox9030224 [pii]
AID - antioxidants-09-00224 [pii]
AID - 10.3390/antiox9030224 [doi]
PST - epublish
SO  - Antioxidants (Basel). 2020 Mar 9;9(3):224. doi: 10.3390/antiox9030224.