PMID- 32192610
OWN - NLM
STAT- MEDLINE
DCOM- 20210104
LR  - 20210104
IS  - 0019-5707 (Print)
IS  - 0019-5707 (Linking)
VI  - 67
IP  - 1
DP  - 2020 Jan
TI  - Immune reconstitution inflammatory syndrome in non-HIV patients with 
      tuberculosis. A case series.
PG  - 143-147
LID - S0019-5707(19)30004-6 [pii]
LID - 10.1016/j.ijtb.2019.02.018 [doi]
AB  - Tuberculosis associated Immune reconstitution inflammatory syndrome (IRIS) in a 
      HIV negative patient can present with a multitude of clinic-radiological 
      presentations that are often confused with drug resistance/treatment failure. 
      Being a diagnosis of exclusion, this clinical entity is often prone to 
      under-diagnosis. We present a series of 5 patients who presented with varied but 
      uncommon IRIS manifestations. High index of suspicion coupled with clinical 
      reasoning and judicious use of phenotypic and genotypic culture methods helped in 
      their timely detection and successful treatment.
CI  - Copyright (c) 2019 Tuberculosis Association of India. Published by Elsevier B.V. 
      All rights reserved.
FAU - Aggarwal, Deepak
AU  - Aggarwal D
AD  - Associate Professor, Dept of Pulmonary Medicine, Govt Medical College & Hospital, 
      Sector-32, Chandigarh, 160030, India. Electronic address: drdeepak@hotmail.com.
FAU - Bhardwaj, Manisha
AU  - Bhardwaj M
AD  - Ex-Senior Resident, Dept of Pulmonary Medicine, Govt Medical College & Hospital, 
      Sector-32, Chandigarh, 160030, India.
FAU - Kumar, Arjun
AU  - Kumar A
AD  - Junior Resident, Dept of Pulmonary Medicine, Govt Medical College & Hospital, 
      Sector-32, Chandigarh, 160030, India.
FAU - Saini, Varinder
AU  - Saini V
AD  - Professor & Head, Dept of Pulmonary Medicine, Govt Medical College & Hospital, 
      Sector-32, Chandigarh, 160030, India.
FAU - Sawal, Nishit
AU  - Sawal N
AD  - Assistant Professor, Dept of General Medicine, Govt Medical College & Hospital, 
      Sector-32, Chandigarh, 160030, India.
LA  - eng
PT  - Journal Article
DEP - 20190306
PL  - India
TA  - Indian J Tuberc
JT  - The Indian journal of tuberculosis
JID - 0373027
RN  - 0 (Antitubercular Agents)
RN  - 0 (Glucocorticoids)
RN  - VB0R961HZT (Prednisone)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Antitubercular Agents/therapeutic use
MH  - Cough/physiopathology
MH  - Drug Resistance, Bacterial/genetics
MH  - Dyspnea/physiopathology
MH  - Glucocorticoids/therapeutic use
MH  - Humans
MH  - Immune Reconstitution Inflammatory Syndrome/*diagnosis/drug 
      therapy/physiopathology
MH  - Male
MH  - Middle Aged
MH  - Middle Lobe Syndrome/*diagnostic imaging/drug therapy
MH  - Mycobacterium tuberculosis/genetics
MH  - Nucleic Acid Amplification Techniques
MH  - Paresis/physiopathology
MH  - Pleural Effusion/physiopathology
MH  - Prednisone/therapeutic use
MH  - Tomography, X-Ray Computed
MH  - Tuberculoma, Intracranial/*diagnostic imaging/drug therapy/physiopathology
MH  - Tuberculosis, Multidrug-Resistant/*diagnosis/drug therapy
MH  - Tuberculosis, Pulmonary/*diagnosis/drug therapy
MH  - Young Adult
OTO - NOTNLM
OT  - Immune reconstitution inflammatory syndrome
OT  - Immunocompetent
OT  - Paradoxical reaction
OT  - Right middle lobe syndrome
OT  - Tuberculosis
EDAT- 2020/03/21 06:00
MHDA- 2021/01/05 06:00
CRDT- 2020/03/21 06:00
PHST- 2019/01/03 00:00 [received]
PHST- 2019/02/28 00:00 [accepted]
PHST- 2020/03/21 06:00 [entrez]
PHST- 2020/03/21 06:00 [pubmed]
PHST- 2021/01/05 06:00 [medline]
AID - S0019-5707(19)30004-6 [pii]
AID - 10.1016/j.ijtb.2019.02.018 [doi]
PST - ppublish
SO  - Indian J Tuberc. 2020 Jan;67(1):143-147. doi: 10.1016/j.ijtb.2019.02.018. Epub 
      2019 Mar 6.