PMID- 32193198
OWN - NLM
STAT- MEDLINE
DCOM- 20210621
LR  - 20220531
IS  - 2052-4897 (Electronic)
IS  - 2052-4897 (Linking)
VI  - 8
IP  - 1
DP  - 2020 Mar
TI  - Air pollution and gestational diabetes mellitus: evidence from cohort studies.
LID - 10.1136/bmjdrc-2019-000937 [doi]
LID - e000937
AB  - Exposure to different air pollutants has been linked to type 2 diabetes mellitus, 
      but the evidence for the association between air pollutants and gestational 
      diabetes mellitus (GDM) has not been systematically evaluated. We systematically 
      retrieved relevant studies from PubMed, Embase, and the Web of Science, and 
      performed stratified analyses and regression analyses. Thirteen studies were 
      analyzed, comprising 1 547 154 individuals from nine retrospective studies, three 
      prospective studies, and one case-control study. Increased exposure to 
      particulate matter </=2.5 microm in diameter (PM(2.5)) was not associated with the 
      increased risk of GDM (adjusted OR 1.03, 95% CI 0.99 to 1.06). However, subgroup 
      analysis showed positive correlation of PM(2.5) exposure in the second trimester 
      with an increased risk of GDM (combined OR 1.07, 95% CI 1.00 to 1.13). Among 
      pollutants other than PM(2.5), significant association between GDM and nitrogen 
      dioxide (NO(2)) (OR 1.05, 95% CI 1.01 to 1.10), nitrogen oxide (NO(x)) (OR 1.03, 
      95% CI 1.01 to 1.05), and sulfur dioxide (SO(2)) (OR 1.09, 95% CI 1.03 to 1.15) 
      was noted. There was no significant association between exposure to black carbon 
      or ozone or carbon monoxide or particulate matter </=10 microm in diameter and GDM. 
      Thus, systematic review of existing evidence demonstrated association of exposure 
      to NO(2), NO(x), and SO(2), and the second trimester exposure of PM(2.5) with the 
      increased risk of GDM. Caution may be exercised while deriving conclusions from 
      existing evidence base because of the limited number and the observational nature 
      of studies.
CI  - (c) Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published 
      by BMJ.
FAU - Tang, Xingyao
AU  - Tang X
AD  - Department of Education, Beijing Tongren Hospital, Beijing, China.
FAU - Zhou, Jian-Bo
AU  - Zhou JB
AUID- ORCID: 0000-0003-2507-9192
AD  - Department of Endocrinology, Beijing Tongren Hospital, Beijing, China 
      jbzhou@ccmu.edu.cn.
FAU - Luo, Fuqiang
AU  - Luo F
AD  - Department of Education, Beijing Tongren Hospital, Beijing, China.
FAU - Han, Yipeng
AU  - Han Y
AD  - Department of Education, Beijing Tongren Hospital, Beijing, China.
FAU - Heianza, Yoriko
AU  - Heianza Y
AD  - Department of Epidemiology, Tulane University School of Public Health and 
      Tropical Medicine, New Orleans, Louisiana, USA.
FAU - Cardoso, Marly Augusto
AU  - Cardoso MA
AD  - Department of Nutrition, School of Public Health, University of Sao Paulo, Sao 
      Paulo, Brazil.
FAU - Qi, Lu
AU  - Qi L
AD  - Department of Epidemiology, Tulane University School of Public Health and 
      Tropical Medicine, New Orleans, Louisiana, USA.
LA  - eng
GR  - U54 GM104940/GM/NIGMS NIH HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PT  - Systematic Review
PL  - England
TA  - BMJ Open Diabetes Res Care
JT  - BMJ open diabetes research & care
JID - 101641391
SB  - IM
MH  - *Air Pollution/adverse effects
MH  - Case-Control Studies
MH  - Cohort Studies
MH  - *Diabetes Mellitus, Type 2
MH  - *Diabetes, Gestational/chemically induced/epidemiology
MH  - Female
MH  - Humans
MH  - Pregnancy
MH  - Prospective Studies
MH  - Retrospective Studies
PMC - PMC7103802
OTO - NOTNLM
OT  - GDM
OT  - accumulated evidence
OT  - air pollution
COIS- Competing interests: None declared.
EDAT- 2020/03/21 06:00
MHDA- 2021/06/22 06:00
PMCR- 2020/03/18
CRDT- 2020/03/21 06:00
PHST- 2019/09/30 00:00 [received]
PHST- 2020/01/07 00:00 [revised]
PHST- 2020/01/14 00:00 [accepted]
PHST- 2020/03/21 06:00 [entrez]
PHST- 2020/03/21 06:00 [pubmed]
PHST- 2021/06/22 06:00 [medline]
PHST- 2020/03/18 00:00 [pmc-release]
AID - 8/1/e000937 [pii]
AID - bmjdrc-2019-000937 [pii]
AID - 10.1136/bmjdrc-2019-000937 [doi]
PST - ppublish
SO  - BMJ Open Diabetes Res Care. 2020 Mar;8(1):e000937. doi: 
      10.1136/bmjdrc-2019-000937.