PMID- 32193634 OWN - NLM STAT- MEDLINE DCOM- 20210623 LR - 20210623 IS - 1436-6215 (Electronic) IS - 1436-6207 (Linking) VI - 59 IP - 8 DP - 2020 Dec TI - The association between frequency of away-from home meals and type 2 diabetes mellitus in rural Chinese adults: the Henan Rural Cohort Study. PG - 3815-3825 LID - 10.1007/s00394-020-02212-5 [doi] AB - PURPOSE: There is a paucity of data on the association between away-from home meals (AFHs) and type 2 diabetes mellitus (T2DM). The aim of this cross-sectional study was to explore the dose-response relationship between AFHs and T2DM in a Chinese population. METHODS: A total of 29,910 participants were enrolled from the Henan Rural Cohort Study. Information on the weekly frequency of AFHs was collected by face-to-face questionnaires. Logistic regression and restricted cubic splines were used to estimate the relationship between the frequencies of AFHs and T2DM. Mediation analysis was performed to examine the contribution of body mass index (BMI) to the frequency of AFH-related T2DM. RESULTS: Compared with those who reported 0 AFHs per week, those who consumed >/= 11 AFHs/week were associated with a 39% increase in the prevalence of T2DM. A nonlinear dose-response relationship between the frequency of AFHs and T2DM was found. Compared with the 0 AFHs/week group, in males, the multivariate odds ratios (OR) and 95% confidence interval (95% CI) of the groups with 11 or more AFHs/week for T2DM were 1.36 (1.01-1.84). However, no such association was found in females. BMI partly mediated the effects of the frequency of AFHs on T2DM, and the proportion explained was 23.4%. CONCLUSIONS: A relationship between the frequency of AFHs and T2DM was observed in the rural Chinese population. An excessive frequency of AFHs was likely to increase the prevalence of T2DM. Meanwhile, BMI partially mediates the effects of the frequency of AFHs on T2DM. TRIAL REGISTRATION: The Henan Rural Cohort Study, ChiCTR-OOC-15006699, Registered 6 July 2015, https://www.chictr.org.cn/showproj.aspx?proj=11375 . FAU - Wang, Bingya AU - Wang B AD - Department of Nutrition and Food Hygiene, College of Public Health, Zhengzhou University, No. 100 Science Road, Zhengzhou, 450001, Henan, People's Republic of China. FAU - Liu, Le AU - Liu L AD - Department of Social Medicine and Healthcare Management, College of Public Health, Zhengzhou University, Zhengzhou, 450001, Henan, People's Republic of China. FAU - Qiao, Dou AU - Qiao D AD - Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou, 450001, Henan, People's Republic of China. FAU - Xue, Yuan AU - Xue Y AD - Department of Nutrition and Food Hygiene, College of Public Health, Zhengzhou University, No. 100 Science Road, Zhengzhou, 450001, Henan, People's Republic of China. FAU - Liu, Xue AU - Liu X AD - Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou, 450001, Henan, People's Republic of China. FAU - Zhang, Dongdong AU - Zhang D AD - Department of Nutrition and Food Hygiene, College of Public Health, Zhengzhou University, No. 100 Science Road, Zhengzhou, 450001, Henan, People's Republic of China. FAU - Liu, Chang AU - Liu C AD - Department of Nutrition and Food Hygiene, College of Public Health, Zhengzhou University, No. 100 Science Road, Zhengzhou, 450001, Henan, People's Republic of China. FAU - Mao, Zhenxing AU - Mao Z AD - Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou, 450001, Henan, People's Republic of China. FAU - Yu, Songcheng AU - Yu S AD - Department of Nutrition and Food Hygiene, College of Public Health, Zhengzhou University, No. 100 Science Road, Zhengzhou, 450001, Henan, People's Republic of China. FAU - Shen, Fang AU - Shen F AD - Department of Nutrition and Food Hygiene, College of Public Health, Zhengzhou University, No. 100 Science Road, Zhengzhou, 450001, Henan, People's Republic of China. FAU - Zhang, Yujing AU - Zhang Y AD - Department of Nutrition and Food Hygiene, College of Public Health, Zhengzhou University, No. 100 Science Road, Zhengzhou, 450001, Henan, People's Republic of China. FAU - Wang, Chongjian AU - Wang C AD - Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou, 450001, Henan, People's Republic of China. FAU - Li, Wenjie AU - Li W AD - Department of Nutrition and Food Hygiene, College of Public Health, Zhengzhou University, No. 100 Science Road, Zhengzhou, 450001, Henan, People's Republic of China. FAU - Li, Xing AU - Li X AD - Department of Nutrition and Food Hygiene, College of Public Health, Zhengzhou University, No. 100 Science Road, Zhengzhou, 450001, Henan, People's Republic of China. lixing530@zzu.edu.cn. LA - eng GR - 2016YFC0900803/the National Key Research and Development Program Precision Medicine Initiative of China/ GR - 81872626/National Natural Science Foundation of China/ GR - 81573151/National Natural Science Foundation of China/ GR - 81573243/National Natural Science Foundation of China/ GR - 182300410293/Henan Natural Science Foundation of China/ GR - 154200510010/Science and Technology Foundation for Innovation Talent of Henan Province/ PT - Journal Article DEP - 20200319 PL - Germany TA - Eur J Nutr JT - European journal of nutrition JID - 100888704 SB - IM MH - Adult MH - China/epidemiology MH - Cohort Studies MH - Cross-Sectional Studies MH - *Diabetes Mellitus, Type 2/epidemiology MH - Female MH - Humans MH - Male MH - Meals MH - Risk Factors MH - Rural Population OTO - NOTNLM OT - BMI OT - Dose-response OT - Frequency of away-from home meals OT - Mediation analysis OT - Rural chinese OT - T2DM EDAT- 2020/03/21 06:00 MHDA- 2021/06/24 06:00 CRDT- 2020/03/21 06:00 PHST- 2019/05/15 00:00 [received] PHST- 2020/02/26 00:00 [accepted] PHST- 2020/03/21 06:00 [pubmed] PHST- 2021/06/24 06:00 [medline] PHST- 2020/03/21 06:00 [entrez] AID - 10.1007/s00394-020-02212-5 [pii] AID - 10.1007/s00394-020-02212-5 [doi] PST - ppublish SO - Eur J Nutr. 2020 Dec;59(8):3815-3825. doi: 10.1007/s00394-020-02212-5. Epub 2020 Mar 19.