PMID- 32193721 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20200928 IS - 2509-8020 (Electronic) IS - 2509-8020 (Linking) VI - 4 IP - 1 DP - 2020 Mar 20 TI - Childhood vitiligo impacts emotional health of parents: a prospective, cross-sectional study of quality of life for primary caregivers. PG - 20 LID - 10.1186/s41687-020-0186-2 [doi] LID - 20 AB - BACKGROUND/OBJECTIVES: Individuals with vitiligo have an increased risk of depression, anxiety, social isolation and detrimental effects on body image/self-esteem. However, assessments of quality of life (QoL) impact have not focused on caregivers of children with vitiligo. To address this, we determined the QoL impact in parents of children with vitiligo to assess the relationship between QoL parameters and disease duration, location, and severity. METHODS: We performed a cross-sectional study involving 123 parents of children diagnosed with vitiligo for at least 3 months, and who presented to the pediatric dermatology clinic of a major United States children's hospital. Parents completed a demographics survey, Quality of Life in a Child's Chronic Disease Questionnaire (QLCCDQ) and Family Dermatology Life Quality Index (FDLQI) to assess QoL measures. The lower the QLCCDQ score and higher the FLDQI score, the more quality of life is impaired. RESULTS: Subject age ranged from 20 to 57, and 13.9% received mental health intervention. QLCCDQ emotional domain scores were most impaired, and severity and location of disease impacted these scores. FDLQI scores decreased as children age, indicating overall parent wellbeing increased as children age. CONCLUSIONS: Childhood vitiligo has great emotional impact on the quality of life of caregivers. Recognizing this will enable dermatologist who primarily care for these patients to incorporate care giver specific interventions during clinical visits. Emotional domain scores for parents of children with vitiligo were the most impaired as much or more than of those seen in parents of children with chronic stable medical disease such as type 1 diabetes and asthma. FAU - Andrade, Gabriela AU - Andrade G AD - Department of Child and Adolescent Psychiatry and Behavioral Sciences, The Children's Hospital of Philadelphia, Philadelphia, PA, USA. FAU - Rangu, Sneha AU - Rangu S AD - Department of Pediatrics, Section of Dermatology, The Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Wood Center 3335, Philadelphia, PA, 19104, USA. FAU - Provini, Lauren AU - Provini L AD - Department of Pediatrics, Section of Dermatology, The Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Wood Center 3335, Philadelphia, PA, 19104, USA. FAU - Putterman, Elana AU - Putterman E AD - Department of Pediatrics, Section of Dermatology, The Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Wood Center 3335, Philadelphia, PA, 19104, USA. AD - Drexel University College of Medicine, Philadelphia, PA, USA. FAU - Gauthier, Abigail AU - Gauthier A AD - Department of Pediatrics, Section of Dermatology, The Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Wood Center 3335, Philadelphia, PA, 19104, USA. AD - University of Alabama School of Medicine, Birmingham, AL, USA. FAU - Castelo-Soccio, Leslie AU - Castelo-Soccio L AUID- ORCID: 0000-0003-3289-446X AD - Department of Pediatrics, Section of Dermatology, The Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Wood Center 3335, Philadelphia, PA, 19104, USA. castelosocciol@email.chop.edu. AD - University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA. castelosocciol@email.chop.edu. LA - eng PT - Journal Article DEP - 20200320 PL - Germany TA - J Patient Rep Outcomes JT - Journal of patient-reported outcomes JID - 101722688 PMC - PMC7082438 OTO - NOTNLM OT - Pediatric dermatology OT - Pigmentary disorders OT - Quality of life OT - Skin differences OT - Vitiligo COIS- The authors declare that have no competing interests. EDAT- 2020/03/21 06:00 MHDA- 2020/03/21 06:01 PMCR- 2020/03/20 CRDT- 2020/03/21 06:00 PHST- 2019/10/30 00:00 [received] PHST- 2020/03/04 00:00 [accepted] PHST- 2020/03/21 06:00 [entrez] PHST- 2020/03/21 06:00 [pubmed] PHST- 2020/03/21 06:01 [medline] PHST- 2020/03/20 00:00 [pmc-release] AID - 10.1186/s41687-020-0186-2 [pii] AID - 186 [pii] AID - 10.1186/s41687-020-0186-2 [doi] PST - epublish SO - J Patient Rep Outcomes. 2020 Mar 20;4(1):20. doi: 10.1186/s41687-020-0186-2.