PMID- 32194283
OWN - NLM
STAT- MEDLINE
DCOM- 20210215
LR  - 20210215
IS  - 1095-9572 (Electronic)
IS  - 1053-8119 (Linking)
VI  - 214
DP  - 2020 Jul 1
TI  - Reconsidering longstanding assumptions about the role of medial prefrontal cortex 
      (MPFC) in social evaluation.
PG  - 116752
LID - S1053-8119(20)30239-1 [pii]
LID - 10.1016/j.neuroimage.2020.116752 [doi]
AB  - The psychological nature of the association between MPFC modulation and social 
      evaluation remains poorly understood. Despite confounds, small samples, and mixed 
      results in existing research, MPFC activation is often interpreted as a 
      reflection of socioemotional association and/or perceived similarity between the 
      self and an evaluation target. The present research addressed issues from the 
      existing literature by examining whether MPFC is modulated by (a) socioemotional 
      associations unconfounded by previous knowledge (memory effects (Study 1, 
      N = 48), repetition suppression (Study 2, N = 43), multi-voxel pattern analysis 
      (Study 1 & 2)) and (b) perceived similarity to self (Study 2). MPFC was modulated 
      by self-reference and trait-relevance, but there was not significant empirical 
      support for the interpretation that MPFC modulation reflects socioemotional 
      association or perceived similarity. These findings highlight the weak basis for 
      prevailing assumptions about the psychological significance of MPFC in social 
      evaluation and the need for studies which test multiple mechanisms.
CI  - Copyright (c) 2020 The Authors. Published by Elsevier Inc. All rights reserved.
FAU - Koski, Jessica E
AU  - Koski JE
AD  - University of Texas at Austin, USA.
FAU - McHaney, Jacie R
AU  - McHaney JR
AD  - University of Texas at Austin, USA.
FAU - Rigney, Anastasia E
AU  - Rigney AE
AD  - University of Texas at Austin, USA.
FAU - Beer, Jennifer S
AU  - Beer JS
AD  - University of Texas at Austin, USA. Electronic address: beerutexas@gmail.com.
LA  - eng
PT  - Journal Article
PT  - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20200316
PL  - United States
TA  - Neuroimage
JT  - NeuroImage
JID - 9215515
SB  - IM
MH  - Adolescent
MH  - Brain Mapping/methods
MH  - Female
MH  - Humans
MH  - Image Processing, Computer-Assisted
MH  - Magnetic Resonance Imaging/methods
MH  - Memory/physiology
MH  - Prefrontal Cortex/*physiology
MH  - *Social Cognition
MH  - Young Adult
OTO - NOTNLM
OT  - MPFC
OT  - Replication
OT  - Self
OT  - Social cognition
OT  - Trait evaluation
EDAT- 2020/03/21 06:00
MHDA- 2021/02/16 06:00
CRDT- 2020/03/21 06:00
PHST- 2019/07/12 00:00 [received]
PHST- 2020/02/13 00:00 [revised]
PHST- 2020/03/14 00:00 [accepted]
PHST- 2020/03/21 06:00 [pubmed]
PHST- 2021/02/16 06:00 [medline]
PHST- 2020/03/21 06:00 [entrez]
AID - S1053-8119(20)30239-1 [pii]
AID - 10.1016/j.neuroimage.2020.116752 [doi]
PST - ppublish
SO  - Neuroimage. 2020 Jul 1;214:116752. doi: 10.1016/j.neuroimage.2020.116752. Epub 
      2020 Mar 16.