PMID- 32197036
OWN - NLM
STAT- MEDLINE
DCOM- 20210621
LR  - 20210621
IS  - 1531-2291 (Electronic)
IS  - 0890-5339 (Linking)
VI  - 34
IP  - 4
DP  - 2020 Apr
TI  - Mechanical Effects of Bone Substitute and Far-Cortical Locking Techniques in 
      2-Part Proximal Humerus Fracture Reconstruction: A Cadaveric Study.
PG  - 199-205
LID - 10.1097/BOT.0000000000001668 [doi]
AB  - OBJECTIVES: To make direct comparisons of the biomechanical properties of a 
      control (CTL) group and implants that were augmented with far cortical locking 
      (FCL), bone substitute material (BSM), and a combination of both (ALL) to 
      determine which fixation is most effective in reducing implant failure. METHODS: 
      The constructs were tested with osteopenic cadaveric specimens in a two-part 
      fracture model. Specimens were subjected to a battery of nondestructive torsion 
      and axial compression tests, followed by a cyclic test. Construct stiffness and 
      cycles to failure were documented, pre- and post-test fluoroscopy was performed, 
      and implant and bone kinematics were quantified. RESULTS: During nondestructive 
      testing, the BSM group exhibited significantly increased torsional and axial 
      stiffness compared with the FCL (P = 0.006, P < 0.001) group and ALL group (P < 
      0.001, P = 0.006). There were no significant differences in resistance to cyclic 
      loading between groups. Fluoroscopic analysis indicated significant differences 
      in the motions of nonlocked cannulated screws (used in BSM and ALL) versus locked 
      screws (used in CTL and FCL). CONCLUSIONS: Patients with poor bone quality and 
      proximal humerus fracture may necessitate added compliance or rigidity to achieve 
      fixation. Both have exhibited favorable biomechanical characteristics in this 
      cadaveric 2-part proximal humerus fracture model.
FAU - Hast, Michael W
AU  - Hast MW
AD  - Biedermann Lab for Orthopaedic Research, Department of Orthopaedic Surgery, 
      University of Pennsylvania, Philadelphia, PA; and.
FAU - Chin, Matthew
AU  - Chin M
AD  - Biedermann Lab for Orthopaedic Research, Department of Orthopaedic Surgery, 
      University of Pennsylvania, Philadelphia, PA; and.
FAU - Schmidt, Elaine C
AU  - Schmidt EC
AD  - Biedermann Lab for Orthopaedic Research, Department of Orthopaedic Surgery, 
      University of Pennsylvania, Philadelphia, PA; and.
FAU - Sanville, Jennifer
AU  - Sanville J
AD  - Biedermann Lab for Orthopaedic Research, Department of Orthopaedic Surgery, 
      University of Pennsylvania, Philadelphia, PA; and.
FAU - Van Osten, George Karl
AU  - Van Osten GK
AD  - Department of Orthopaedic Surgery, North Mississippi Medical Center, Tupelo, MS.
FAU - Mehta, Samir
AU  - Mehta S
AD  - Biedermann Lab for Orthopaedic Research, Department of Orthopaedic Surgery, 
      University of Pennsylvania, Philadelphia, PA; and.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Orthop Trauma
JT  - Journal of orthopaedic trauma
JID - 8807705
RN  - 0 (Bone Substitutes)
SB  - IM
MH  - Biomechanical Phenomena
MH  - Bone Plates
MH  - Bone Screws
MH  - *Bone Substitutes
MH  - Cadaver
MH  - Fracture Fixation, Internal
MH  - Humans
MH  - Humerus
EDAT- 2020/03/21 06:00
MHDA- 2021/06/22 06:00
CRDT- 2020/03/21 06:00
PHST- 2020/03/21 06:00 [entrez]
PHST- 2020/03/21 06:00 [pubmed]
PHST- 2021/06/22 06:00 [medline]
AID - 00005131-202004000-00006 [pii]
AID - 10.1097/BOT.0000000000001668 [doi]
PST - ppublish
SO  - J Orthop Trauma. 2020 Apr;34(4):199-205. doi: 10.1097/BOT.0000000000001668.