PMID- 32198545
OWN - NLM
STAT- MEDLINE
DCOM- 20200326
LR  - 20201210
IS  - 1573-2959 (Electronic)
IS  - 0167-6369 (Linking)
VI  - 192
IP  - 4
DP  - 2020 Mar 20
TI  - Evaluation of phytotherapeutic activities and phytochemical content of Phormidium 
      autumnale Gomont from natural freshwater sources.
PG  - 244
LID - 10.1007/s10661-020-8207-4 [doi]
AB  - The information available on microalgae-sourced compounds, especially antibiotics 
      and other bioactive compounds, and their potential commercial applications is 
      still insufficient. In this study, antibacterial activity, metabolites, and 
      molecular characterization of Phormidium autumnale, which was isolated from 
      samples collected from different natural freshwater sources in Ankara, Turkey, 
      were investigated. Sequencing results of 16s rDNA confirmed the molecular 
      identification of P. autumnale by 99%. It was determined that the peak values of 
      some phenolic compounds and cyclic peptides were consistent with the 
      1653-1389 cm(-1) band regions in the FTIR spectra of the species. The 
      antibacterial activities of P. autumnale cyanobacteria (CBA) extracts that were 
      obtained by using different solvents were tested on Escherichia coli, 
      Staphylococcus epidermidis, methicillin-resistant (MR) Staphylococcus aureus, 
      Streptococcus agalactiae, and Enterococcus faecalis by using a disc diffusion 
      method. Also, the minimum inhibition concentration (MIC) and antimicrobial 
      indexes of all extracts were determined. It was found that P. autumnale methanol 
      extracts showed antibacterial activity on all test bacteria, whereas acetone 
      extracts showed effects only on E. coli. For the inhibition of MR S. aureus, the 
      control methanol extract was found to give very similar results to those 
      exhibited by the control antibiotics, and the antimicrobial index results were 
      determined to be 58.7-67.5%. According to the results of the analysis of methanol 
      extract, gentisic acid, vanillic acid, 4-hydroxybenzoic acid, p-coumaric acid, 
      and catechin (especially phenolic compounds) were determined to be the active 
      compounds. It can be concluded that P. autumnale is an alternative to current 
      commercial applications as an antibacterial agent in phytotherapy.
FAU - Yalcin, Dilek
AU  - Yalcin D
AUID- ORCID: 0000-0003-2127-8186
AD  - Faculty of Education, Secondary School Science and Mathematics Education, Biology 
      Education, Gazi University, Ankara, Turkey. dilekduygu06@hotmail.com.
FAU - Turk Katircioglu, Hikmet
AU  - Turk Katircioglu H
AD  - Faculty of Education, Secondary School Science and Mathematics Education, Biology 
      Education, Gazi University, Ankara, Turkey.
FAU - Ozer, Tulay
AU  - Ozer T
AD  - Kaman High School of Applied Science, Kirsehir Ahi Evran University, Kirsehir, 
      Turkey.
FAU - Pourhassan Shamchi, Minoo
AU  - Pourhassan Shamchi M
AD  - Faculty of Education, Secondary School Science and Mathematics Education, Biology 
      Education, Gazi University, Ankara, Turkey.
FAU - Acikgoz Erkaya, Ilkay
AU  - Acikgoz Erkaya I
AD  - Faculty of Architecture and Engineering, Department of Environmental Engineering, 
      Kirsehir Ahi Evran University, Kirsehir, Turkey.
LA  - eng
PT  - Journal Article
DEP - 20200320
PL  - Netherlands
TA  - Environ Monit Assess
JT  - Environmental monitoring and assessment
JID - 8508350
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Phytochemicals)
RN  - Phormidium autumnale
SB  - IM
MH  - Anti-Bacterial Agents/isolation & purification/pharmacology
MH  - *Cyanobacteria/chemistry/genetics
MH  - *Escherichia coli/drug effects
MH  - Fresh Water
MH  - Microbial Sensitivity Tests
MH  - Phormidium
MH  - *Phytochemicals/isolation & purification/pharmacology
MH  - Phytotherapy
MH  - *Staphylococcus aureus/drug effects
MH  - Turkey
OTO - NOTNLM
OT  - Antibacterial activity
OT  - Cyanobacteria
OT  - Molecular characterization
OT  - Phormidium autumnale
EDAT- 2020/03/22 06:00
MHDA- 2020/03/27 06:00
CRDT- 2020/03/22 06:00
PHST- 2019/11/10 00:00 [received]
PHST- 2020/03/04 00:00 [accepted]
PHST- 2020/03/22 06:00 [entrez]
PHST- 2020/03/22 06:00 [pubmed]
PHST- 2020/03/27 06:00 [medline]
AID - 10.1007/s10661-020-8207-4 [pii]
AID - 10.1007/s10661-020-8207-4 [doi]
PST - epublish
SO  - Environ Monit Assess. 2020 Mar 20;192(4):244. doi: 10.1007/s10661-020-8207-4.