PMID- 32198606 OWN - NLM STAT- MEDLINE DCOM- 20210706 LR - 20210706 IS - 1573-6660 (Electronic) IS - 1040-7308 (Linking) VI - 30 IP - 2 DP - 2020 Jun TI - A Meta-Analysis of Neuropsychological Predictors of Outcome Following Stroke and Other Non-Traumatic Acquired Brain Injuries in Adults. PG - 194-223 LID - 10.1007/s11065-020-09433-9 [doi] AB - A number of cognitive abilities have been reported to predict outcome following a non-traumatic acquired brain injury (ABI) in adults. However, the results are inconsistent. Furthermore, the unique and combined capacity of these cognitive abilities to predict ABI outcome has not been evaluated. Consequently, we employed meta-analysis and multiple regression to evaluate the capacity of various neuropsychological domains to predict two separate outcome variables in adults: (1) activities of daily living; and (2) quality of life. Based on the activities of daily living meta-analysis (N = 2384), we estimated the following significant bivariate effects: memory (r = .31, 95% CI: .20/.41]), language (r = .33, 95% CI:.26/.40), attention (r = .38, 95% CI: .30/.46]), executive functions (r = .29, 95% CI: .19/.39]), and visuospatial abilities (r = .41, 95% CI: .34/ .48). Based on the quality of life meta-analysis (N = 1037), we estimated the following significant bivariate effects: memory (r = .12, 95% CI: .03/.20]), language (r = .19, 95% CI: .06/ .32), attention (r = .30, 95% CI: .16/.44]), executive functions (r = .24, 95% CI: .12/.37) and visuospatial/constructional abilities (r = .30, 95% CI: .14/.46). Meta-analytic structural equation modelling (metaSEM) identified two significant, unique predictors of activities of daily living, attention and visuospatial abilities, and the model accounted for 21% of the variance (multiple R(2) = .21, 95%CI: .16/.26). For the corresponding quality of life metaSEM, no statistically significant unique predictors were identified, however, a significant multiple correlation was observed, multiple R(2) = .11 (95%CI: 04/.18). We conclude that practitioners may be able to predict, with some degree of accuracy, functional outcome following a stroke and other non-traumatic ABI in adults. We also provide some critical commentary on the nature and quality of the measures used in this area of research to represent the cognitive dimensions of interest. FAU - Watson, Prue A AU - Watson PA AD - School of Psychological Science, University of Western Australia, 35 Stirling Highway, Crawley, Western Australia, 6009. FAU - Gignac, Gilles E AU - Gignac GE AUID- ORCID: 0000-0002-4900-6855 AD - School of Psychological Science, University of Western Australia, 35 Stirling Highway, Crawley, Western Australia, 6009. gilles.gignac@uwa.edu.au. FAU - Weinborn, Michael AU - Weinborn M AD - School of Psychological Science, University of Western Australia, 35 Stirling Highway, Crawley, Western Australia, 6009. AD - School of Medical and Health Sciences, Edith Cowan University, Joondalup, Western Australia. FAU - Green, Sarah AU - Green S AD - School of Psychological Science, University of Western Australia, 35 Stirling Highway, Crawley, Western Australia, 6009. FAU - Pestell, Carmela AU - Pestell C AD - School of Psychological Science, University of Western Australia, 35 Stirling Highway, Crawley, Western Australia, 6009. LA - eng PT - Journal Article PT - Meta-Analysis PT - Review DEP - 20200320 PL - United States TA - Neuropsychol Rev JT - Neuropsychology review JID - 9009029 SB - IM MH - Activities of Daily Living MH - Adult MH - Attention MH - Brain Injuries/*rehabilitation MH - Executive Function MH - Female MH - Humans MH - Male MH - Memory MH - Neuropsychological Tests MH - Quality of Life MH - Recovery of Function MH - Stroke/*psychology MH - *Stroke Rehabilitation OTO - NOTNLM OT - Acquired brain injury OT - Activities of daily living OT - Functional outcomes OT - Neuropsychological assessment OT - Stroke EDAT- 2020/03/22 06:00 MHDA- 2021/07/07 06:00 CRDT- 2020/03/22 06:00 PHST- 2018/11/23 00:00 [received] PHST- 2020/02/23 00:00 [accepted] PHST- 2020/03/22 06:00 [pubmed] PHST- 2021/07/07 06:00 [medline] PHST- 2020/03/22 06:00 [entrez] AID - 10.1007/s11065-020-09433-9 [pii] AID - 10.1007/s11065-020-09433-9 [doi] PST - ppublish SO - Neuropsychol Rev. 2020 Jun;30(2):194-223. doi: 10.1007/s11065-020-09433-9. Epub 2020 Mar 20.