PMID- 32201464
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220413
IS  - 1011-6842 (Print)
IS  - 1011-6842 (Linking)
VI  - 36
IP  - 2
DP  - 2020 Mar
TI  - Olfactory Dysfunction in Patients with Ischemic Heart Failure.
PG  - 133-139
LID - 10.6515/ACS.202003_36(2).20190812B [doi]
AB  - BACKGROUND: Heart failure (HF) is one of the leading causes of morbidity and 
      mortality in the elderly. Early recognition, treatment, and elimination of 
      potentially modifiable risk factors for HF are crucial for improving both 
      survival and health-related life quality in those with HF. We aimed to 
      investigate whether or not there is an association between olfactory function and 
      the presence and severity of ischemic HF. METHODS: The study included 40 patients 
      with ischemic HF and 40 controls with coronary artery disease but without HF. All 
      patients and controls underwent detailed physical and echocardiographic 
      examinations. The Sniffin' Stick test was used to evaluate olfactory function. 
      RESULTS: Threshold-discrimination-identification (TDI) score was significantly 
      lower in the patients with HF than in the controls (16.4 +/- 7.8 vs. 33.3 +/- 5.2, p 
      < 0.001). When patients with ischemic HF were categorized according to New York 
      Heart Association (NYHA) class, the TDI scores were significantly higher in the 
      patients with NYHA class 1 HF compared to those with NYHA class 3 HF (23.4 +/- 0.9 
      vs. 8.8 +/- 7.0, p < 0.001). We also found a significant negative correlation 
      between the TDI score and NYHA class (r = -0.769, p < 0.001) and a positive 
      correlation between the TDI score and left ventricular ejection fraction (r = 
      0.902, p < 0.001). CONCLUSIONS: Olfactory function was severely impaired in the 
      patients with ischemic HF in this study. In addition, olfactory dysfunction in 
      the patients with ischemic HF was significantly correlated with the severity of 
      HF.
FAU - Aksit, Ercan
AU  - Aksit E
AD  - Department of Cardiology.
FAU - Cil, Ozge Caglar
AU  - Cil OC
AD  - Department of Otorhinolaryngology, Canakkale Onsekiz Mart University Faculty of 
      Medicine, Canakkale, Turkey.
LA  - eng
PT  - Journal Article
PL  - China (Republic : 1949- )
TA  - Acta Cardiol Sin
JT  - Acta Cardiologica Sinica
JID - 101687085
PMC - PMC7062812
OTO - NOTNLM
OT  - Cerebral hypoperfusion
OT  - Coronary artery disease
OT  - Heart failure
OT  - Olfactory dysfunction
OT  - Severity
EDAT- 2020/03/24 06:00
MHDA- 2020/03/24 06:01
PMCR- 2020/03/01
CRDT- 2020/03/24 06:00
PHST- 2020/03/24 06:00 [entrez]
PHST- 2020/03/24 06:00 [pubmed]
PHST- 2020/03/24 06:01 [medline]
PHST- 2020/03/01 00:00 [pmc-release]
AID - 10.6515/ACS.202003_36(2).20190812B [doi]
PST - ppublish
SO  - Acta Cardiol Sin. 2020 Mar;36(2):133-139. doi: 
      10.6515/ACS.202003_36(2).20190812B.