PMID- 32205700
OWN - NLM
STAT- MEDLINE
DCOM- 20201208
LR  - 20210115
IS  - 1528-1159 (Electronic)
IS  - 0362-2436 (Linking)
VI  - 45
IP  - 18
DP  - 2020 Sep 15
TI  - Evaluating the Minimal Clinically Important Difference of EQ-5D-3L in Patients 
      With Degenerative Lumbar Spinal Stenosis: A Swiss Prospective Multicenter Cohort 
      Study.
PG  - 1309-1316
LID - 10.1097/BRS.0000000000003501 [doi]
AB  - STUDY DESIGN: Analysis of a prospective, multicenter cohort study. OBJECTIVE: The 
      aim of our study was to compare thresholds of published minimal clinically 
      important differences (MCID) for the three-level EuroQol-5D health survey 
      (EQ-5D-3L) summary index (range -0.53 to 1.00) with our anchor-based estimate and 
      evaluate how useful these thresholds are in determining treatment success in 
      patients undergoing surgery for degenerative lumbar spinal stenosis (DLSS). 
      SUMMARY OF BACKGROUND DATA: MCID values for EQ-5D-3L are specific to the 
      underlying disease and only three studies have been published for DLSS patients 
      reporting different values. METHODS: Patients of the multicenter Lumbar Stenosis 
      Outcome Study with confirmed DLSS undergoing first-time decompression or fusion 
      surgery with 12-month follow-up were enrolled in this study. To calculate MCID we 
      used the Spinal Stenosis Measure satisfaction subscale as anchor. RESULTS: For 
      this study, 364 patients met the inclusion criteria; of these, 196 were very 
      satisfied, 72 moderately satisfied, 43 somewhat satisfied, and 53 unsatisfied 12 
      months after surgery. The MCID calculation estimated for EQ-5D-3L a value of 
      0.19. Compared with published MCID values (ranging from 0.30 to 0.52), our 
      estimation is less restrictive. CONCLUSIONS: In patients with LSS undergoing 
      surgery, we estimated an MCID value for EQ-5D-3L summary index of 0.19 with the 
      help of the average change anchor-based method, which we find to be the most 
      suitable method for assessing patient change scores. LEVEL OF EVIDENCE: 3.
FAU - Burgstaller, Jakob M
AU  - Burgstaller JM
AD  - Horten Centre for Patient Oriented Research and Knowledge Transfer, University of 
      Zurich, Zurich, Switzerland.
FAU - Wertli, Maria M
AU  - Wertli MM
AD  - Horten Centre for Patient Oriented Research and Knowledge Transfer, University of 
      Zurich, Zurich, Switzerland.
AD  - Division of General Internal Medicine, Bern University Hospital, Bern University, 
      Bern, Switzerland.
FAU - Ulrich, Nils H
AU  - Ulrich NH
AD  - Horten Centre for Patient Oriented Research and Knowledge Transfer, University of 
      Zurich, Zurich, Switzerland.
FAU - Pichierri, Giuseppe
AU  - Pichierri G
AD  - Horten Centre for Patient Oriented Research and Knowledge Transfer, University of 
      Zurich, Zurich, Switzerland.
FAU - Brunner, Florian
AU  - Brunner F
AD  - Department of Physical Medicine and Rheumatology, Balgrist University Hospital, 
      Zurich, Switzerland.
FAU - Farshad, Mazda
AU  - Farshad M
AD  - Spine Division, Balgrist University Hospital, Zurich, Switzerland.
FAU - Porchet, Francois
AU  - Porchet F
AD  - Spine Unit, Department of Orthopedic- and Neurosurgery, Schulthess Clinic, 
      Zurich, Switzerland.
FAU - Steurer, Johann
AU  - Steurer J
AD  - Horten Centre for Patient Oriented Research and Knowledge Transfer, University of 
      Zurich, Zurich, Switzerland.
FAU - Gravestock, Isaac
AU  - Gravestock I
AD  - Horten Centre for Patient Oriented Research and Knowledge Transfer, University of 
      Zurich, Zurich, Switzerland.
CN  - LSOS Study Group
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
PL  - United States
TA  - Spine (Phila Pa 1976)
JT  - Spine
JID - 7610646
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Cohort Studies
MH  - Female
MH  - Health Surveys/methods/*standards
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Minimal Clinically Important Difference
MH  - Pain Measurement/methods/standards
MH  - Prospective Studies
MH  - Quality of Life
MH  - Spinal Stenosis/diagnosis/*epidemiology/*surgery
MH  - Switzerland/epidemiology
MH  - Treatment Outcome
EDAT- 2020/03/25 06:00
MHDA- 2020/12/15 06:00
CRDT- 2020/03/25 06:00
PHST- 2020/03/25 06:00 [pubmed]
PHST- 2020/12/15 06:00 [medline]
PHST- 2020/03/25 06:00 [entrez]
AID - 00007632-202009150-00019 [pii]
AID - 10.1097/BRS.0000000000003501 [doi]
PST - ppublish
SO  - Spine (Phila Pa 1976). 2020 Sep 15;45(18):1309-1316. doi: 
      10.1097/BRS.0000000000003501.