PMID- 32207242
OWN - NLM
STAT- MEDLINE
DCOM- 20210624
LR  - 20210624
IS  - 2162-3279 (Electronic)
VI  - 10
IP  - 5
DP  - 2020 May
TI  - Effect of mindfulness meditation protocol in subjects with various psychometric 
      characteristics at high altitude.
PG  - e01604
LID - 10.1002/brb3.1604 [doi]
LID - e01604
AB  - INTRODUCTION: Incidence of high altitude-related sickness is increasing due to 
      more number of people visiting the areas of high altitude which may result in 
      life-threatening conditions including acute mountain sickness (AMS), high 
      altitude pulmonary edema (HAPE), high altitude cerebral edema (HACE), and 
      High-altitude pulmonary hypertension (HAPH). We hypothesized that an advanced 
      yoga regimen may be beneficial in dealing with the physiology of acclimatization. 
      METHODS: Anthropometric, Biochemical, and Psychological assessments were carried 
      out in 48 participants before and after the advance meditation program (AMP) in 
      the experimental group. Individuals with an age range of 20-65 years with no 
      comorbidities were included in the study. Participants were exposed to AMP for 
      4 days. All assessments were carried out at the baseline and after the course. 
      Prakriti was constituted for all participants using a standard questionnaire. The 
      study was carried out after obtaining the written informed consent as per the 
      guidelines outlined by the Institute Ethics Committee. RESULTS: Po2 and glucose 
      levels were found significantly reduced along with changes in the Happiness 
      index, anxiety, and mental well-being. However, participants with lowered Po2, 
      after 4 days of mindfulness intervention, showed a positive outcome measured by 
      the established scales of anxiety, happiness, and information processing. 
      Psychometric or Prakriti wise analysis revealed that subject with "Pitta" 
      constitution exposed to high altitude and advance meditation showed changes in 
      more parameters than "Vatta" or "Kapha" Constitution. CONCLUSIONS: Advance 
      meditation in the high altitude zone confers biochemical and neuro-cognitive 
      benefits. Molecular studies may require to understand the role of hypoxic 
      condition in improving the disease state.
CI  - (c) 2020 The Authors. Brain and Behavior published by Wiley Periodicals, Inc.
FAU - Bhanushali, Disha
AU  - Bhanushali D
AD  - Ved Vignan Maha Vidya Peeth, Sri Sri Institute of Advanced Research, Bangaluru, 
      India.
FAU - Tyagi, Rahul
AU  - Tyagi R
AD  - Neuroscience Research Lab, Department of Neurology, Postgraduate Institute of 
      Medical Education and Research, Chandigarh, India.
FAU - Limaye Rishi Nityapragya, Nitin
AU  - Limaye Rishi Nityapragya N
AUID- ORCID: 0000-0003-4495-8918
AD  - Ved Vignan Maha Vidya Peeth, Sri Sri Institute of Advanced Research, Bangaluru, 
      India.
FAU - Anand, Akshay
AU  - Anand A
AUID- ORCID: 0000-0001-9003-3532
AD  - Neuroscience Research Lab, Department of Neurology, Postgraduate Institute of 
      Medical Education and Research, Chandigarh, India.
LA  - eng
PT  - Journal Article
DEP - 20200323
PL  - United States
TA  - Brain Behav
JT  - Brain and behavior
JID - 101570837
SB  - IM
MH  - Adult
MH  - Aged
MH  - Altitude
MH  - *Altitude Sickness/therapy
MH  - *Brain Edema
MH  - Humans
MH  - *Meditation
MH  - Middle Aged
MH  - *Mindfulness
MH  - Psychometrics
MH  - Young Adult
PMC - PMC7218243
OTO - NOTNLM
OT  - High altitude
OT  - Prakriti
OT  - SKY
OT  - advance meditation
OT  - pO2
COIS- The authors declare that they have no competing interests.
EDAT- 2020/03/25 06:00
MHDA- 2021/06/25 06:00
PMCR- 2020/03/23
CRDT- 2020/03/25 06:00
PHST- 2019/11/05 00:00 [received]
PHST- 2020/02/04 00:00 [revised]
PHST- 2020/02/29 00:00 [accepted]
PHST- 2020/03/25 06:00 [pubmed]
PHST- 2021/06/25 06:00 [medline]
PHST- 2020/03/25 06:00 [entrez]
PHST- 2020/03/23 00:00 [pmc-release]
AID - BRB31604 [pii]
AID - 10.1002/brb3.1604 [doi]
PST - ppublish
SO  - Brain Behav. 2020 May;10(5):e01604. doi: 10.1002/brb3.1604. Epub 2020 Mar 23.