PMID- 32212830 OWN - NLM STAT- MEDLINE DCOM- 20201215 LR - 20201215 IS - 1600-0455 (Electronic) IS - 0284-1851 (Linking) VI - 61 IP - 12 DP - 2020 Dec TI - Peripheral bronchial luminal conspicuity on dynamic-ventilation computed tomography: association with radiation doses and temporal resolution by using an ex vivo porcine lung phantom. PG - 1608-1617 LID - 10.1177/0284185120911186 [doi] AB - BACKGROUND: It is still unclear which image reconstruction algorithm is appropriate for peripheral bronchial luminal conspicuity (PBLC) on dynamic-ventilation computed tomography (DVCT). PURPOSE: To assess the influence of radiation doses and temporal resolution (TR) on the association between movement velocity (MV) and PBLC on DVCT. MATERIAL AND METHODS: An ex vivo porcine lung phantom with simulated respiratory movement was scanned by 320-row CT at 240 mA and 10 mA. Peak and dip CT density and luminal area adjusted by values at end-inspiration (CTD(peak) and CTD(dip), luminal area ratio [LAR]) for PBLC and MVs were measured and visual scores (VS) were obtained at 12 measurement points on 13 frame images obtained at half and full reconstructions (TR 340 and 190 ms) during expiration. Size-specific dose estimate (SSDE) was applied to presume radiation dose. VS, CTD(peak), CTD(dip), LAR, and their cross-correlation coefficients with MV (CCC) were compared among four methods with combinations of two reconstruction algorithms and two doses. RESULTS: The dose at 10 mA was presumed as 26 mA by SSDE for standard proportion adults. VS, CTD(dip), CTD(peak), and LAR with half reconstruction at 10 mA (2.52 +/- 0.59, 1.016 +/- 0.221, 0.948 +/- 0.103, and 0.990 +/- 0.527) were similar to those at 240 mA except for VS, and different from those with full reconstruction at both doses (2.24 +/- 0.85, 0.830 +/- 0.209, 0.986 +/- 0.065, and 1.012 +/- 0.438 at 240 mA) (P < 0.05). CCC for CTD(dip) with half reconstruction (-0.024 +/- 0.552) at 10 mA was higher compared with full reconstruction (-0.503 +/- 0.291) (P < 0.05). CONCLUSION: PBLC with half reconstruction at 10 mA was comparable to that at 240 mA and better than those with full reconstruction on DVCT. FAU - Nagatani, Yukihiro AU - Nagatani Y AUID- ORCID: 0000-0002-1110-963X AD - Department of Radiology, Shiga University of Medical Science, Otsu, Shiga, Japan. FAU - Yoshigoe, Makoto AU - Yoshigoe M AD - Department of Radiology, Shiga University of Medical Science, Otsu, Shiga, Japan. FAU - Tsukagoshi, Shinsuke AU - Tsukagoshi S AD - CT System Division, Canon Medical Systems, Otawara, Tochigi, Japan. FAU - Ushio, Noritoshi AU - Ushio N AD - Department of Radiology, Shiga University of Medical Science, Otsu, Shiga, Japan. FAU - Ohashi, Kohei AU - Ohashi K AD - Department of Radiology, Shiga University of Medical Science, Otsu, Shiga, Japan. FAU - Nitta, Norihisa AU - Nitta N AD - Department of Radiology, Shiga University of Medical Science, Otsu, Shiga, Japan. FAU - Kimoto, Tatsuya AU - Kimoto T AD - Center for Medical Research and Development, Canon Medical Systems, Otawara, Tochigi, Japan. FAU - Uranishi, Ayumi AU - Uranishi A AD - CT System Division, Canon Medical Systems, Otawara, Tochigi, Japan. FAU - Sato, Shigetaka AU - Sato S AUID- ORCID: 0000-0001-6460-0142 AD - Department of Radiology, Shiga University of Medical Science, Otsu, Shiga, Japan. FAU - Mayumi, Masayuki AU - Mayumi M AD - Department of Radiology, Shiga University of Medical Science, Otsu, Shiga, Japan. FAU - Yamashiro, Tsuneo AU - Yamashiro T AUID- ORCID: 0000-0002-1904-2548 AD - Department of Radiology, Graduate School of Medical Science, University of the Ryukyus, Nishihara, Okinawa, Japan. FAU - Moriya, Hiroshi AU - Moriya H AD - Department of Radiology, Ohara General Hospital, Fukushima, Fukushima, Japan. FAU - Murata, Kiyoshi AU - Murata K AD - Department of Radiology, Shiga University of Medical Science, Otsu, Shiga, Japan. FAU - Watanabe, Yoshiyuki AU - Watanabe Y AD - Department of Radiology, Shiga University of Medical Science, Otsu, Shiga, Japan. CN - investigators of ACTIve study group LA - eng PT - Journal Article DEP - 20200325 PL - England TA - Acta Radiol JT - Acta radiologica (Stockholm, Sweden : 1987) JID - 8706123 SB - IM MH - Algorithms MH - Animals MH - Bronchi/*diagnostic imaging MH - In Vitro Techniques MH - Lung/*diagnostic imaging MH - Phantoms, Imaging MH - Radiation Dosage MH - Radiographic Image Interpretation, Computer-Assisted MH - Respiration MH - Retrospective Studies MH - Swine MH - Tomography, X-Ray Computed/*methods OTO - NOTNLM OT - Dynamic ventilation computed tomography OT - half reconstruction OT - iterative reconstruction OT - peripheral bronchial lumen OT - ultra-low-dose scanning EDAT- 2020/03/28 06:00 MHDA- 2020/12/16 06:00 CRDT- 2020/03/28 06:00 PHST- 2020/03/28 06:00 [pubmed] PHST- 2020/12/16 06:00 [medline] PHST- 2020/03/28 06:00 [entrez] AID - 10.1177/0284185120911186 [doi] PST - ppublish SO - Acta Radiol. 2020 Dec;61(12):1608-1617. doi: 10.1177/0284185120911186. Epub 2020 Mar 25.