PMID- 32216759
OWN - NLM
STAT- MEDLINE
DCOM- 20200807
LR  - 20231113
IS  - 1471-2458 (Electronic)
IS  - 1471-2458 (Linking)
VI  - 20
IP  - 1
DP  - 2020 Mar 26
TI  - Prevalence of abnormal glucose metabolism among adults attending an outpatient 
      department at a tertiary referral hospital in Swaziland: a cross-sectional study.
PG  - 392
LID - 10.1186/s12889-020-08489-9 [doi]
LID - 392
AB  - BACKGROUND: The exact prevalence of type 2 diabetes mellitus (T2DM) and 
      pre-diabetes in Swaziland remains unknown. Estimates suggest that the prevalence 
      rate of type 2 diabetes mellitus is between 2.5 and 6.0% in Swaziland. The 
      disparity in these estimates is due to a lack of quality data but the prevalence 
      of diabetes is increasing in Swaziland. This study estimates the prevalence of 
      type 2 diabetes mellitus and pre-diabetes among patients in a tertiary hospital 
      in Manzini, Swaziland. METHODS: A cross-sectional observational survey was used 
      to estimate the crude and age-adjusted prevalence rates of diabetes and 
      pre-diabetes (impaired fasting glucose (IFG) and impaired glucose tolerance 
      (IGT)) in the Manzini regional referral hospital of Swaziland. Diabetes was 
      defined as a fasting blood glucose (FBG) >/= 7.0 mmol/L (126 mg/dL) and 
      pre-diabetes was defined as an FBG of 6.1-6.9 mmol/L (110-125 mg/dL) and an FBG 
      < 7.0 mmol/L (< 126 mg/dL), respectively for IFG and IGT. A random sample of 385 
      participants was used. Data analysis was done using SPSS version 26 and the level 
      of statistical significance was set at alpha < 0.05. RESULTS: The crude prevalence of 
      type 2 diabetes mellitus and pre-diabetes was 7.3% [95% CI 4.9-10.3] and 6.5% 
      [95% CI 4.2-9.4], respectively, with clear gender differences in the prevalence 
      of diabetes (men 1.6% vs women 5.7%, p = 0.001). On the other hand, significantly 
      more men (3.6%) had pre-diabetes than women (2.9%) (p = 0.004). The overall 
      age-adjusted prevalence rates of type 2 diabetes mellitus and pre-diabetes were 
      3.9 and 3.8%, respectively. Among the diabetic group, 3 (10.7%) had known T2DM, 
      whereas 25 (89.3%) were newly diagnosed during the study. Advancing age, gender, 
      raised blood pressure, abnormal body mass index, and wealth index were 
      significant risk factors for T2DM or prediabetes. CONCLUSION: The prevalence of 
      type 2 diabetes mellitus among adult outpatients in the Raleigh Fitkin Memorial 
      hospital was higher than previously reported in the health facility in Manzini; 
      suggesting the need for routine T2DM screening at outpatient departments.
FAU - Gbadamosi, Mojeed Akorede
AU  - Gbadamosi MA
AD  - Discipline of Public Health Medicine, School of Nursing and Public Health, 
      University of KwaZulu-Natal, Durban, South Africa. 217081323@stu.ukzn.ac.za.
FAU - Tlou, Boikhutso
AU  - Tlou B
AD  - Discipline of Public Health Medicine, School of Nursing and Public Health, 
      University of KwaZulu-Natal, Durban, South Africa.
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20200326
PL  - England
TA  - BMC Public Health
JT  - BMC public health
JID - 100968562
SB  - IM
MH  - Adult
MH  - Ambulatory Care
MH  - Cross-Sectional Studies
MH  - Diabetes Mellitus, Type 2/*epidemiology
MH  - Eswatini/epidemiology
MH  - Female
MH  - Glucose Intolerance/*epidemiology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Outpatients/*statistics & numerical data
MH  - Prediabetic State/*epidemiology
MH  - Prevalence
MH  - Tertiary Care Centers
PMC - PMC7098143
OTO - NOTNLM
OT  - Abnormal glucose metabolism
OT  - Diabetes
OT  - Pre-diabetes
OT  - Prevalence
OT  - Swaziland
COIS- The authors declare that they have no competing interests.
EDAT- 2020/03/29 06:00
MHDA- 2020/08/08 06:00
PMCR- 2020/03/26
CRDT- 2020/03/29 06:00
PHST- 2019/08/28 00:00 [received]
PHST- 2020/03/09 00:00 [accepted]
PHST- 2020/03/29 06:00 [entrez]
PHST- 2020/03/29 06:00 [pubmed]
PHST- 2020/08/08 06:00 [medline]
PHST- 2020/03/26 00:00 [pmc-release]
AID - 10.1186/s12889-020-08489-9 [pii]
AID - 8489 [pii]
AID - 10.1186/s12889-020-08489-9 [doi]
PST - epublish
SO  - BMC Public Health. 2020 Mar 26;20(1):392. doi: 10.1186/s12889-020-08489-9.