PMID- 32226763
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200928
IS  - 2214-2509 (Print)
IS  - 2214-2509 (Electronic)
IS  - 2214-2509 (Linking)
VI  - 19
DP  - 2020
TI  - Intramedullary spinal cord lesions in an immunocompromised host due to 
      Mycobacterium haemophilum.
PG  - e00674
LID - 10.1016/j.idcr.2019.e00674 [doi]
LID - e00674
AB  - Mycobacterium haemophilum is a slow growing acid-fast bacillus (AFB) in the 
      nontuberculous mycobacteria (NTM) group. M. haemophilum typically causes 
      cervicofacial lymphadenitis in children, cutaneous diseases, septic arthritis and 
      osteomyelitis. However, it rarely causes isolated spinal cord disease. We report 
      the first case, to our knowledge, of isolated intramedullary spinal lesions 
      secondary to M. haemophilum. This case involved a patient with newly diagnosed 
      human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS). He 
      developed significant immune reconstitution inflammatory syndrome (IRIS) during 
      his treatment. M. haemophilum should be on the differential for isolated 
      intramedullary spinal lesions, particularly in immunocompromised patients. Given 
      our patient's severe IRIS, patients with HIV and M. haemophilum infection should 
      be closely monitored for IRIS and treated aggressively. In high risk 
      circumstances such as M. haemophilum spinal disease in patients with HIV, 
      clinicians should consider pre-emptive treatment for IRIS.
CI  - (c) 2019 The Authors.
FAU - Kon, Shelley
AU  - Kon S
AD  - University of Colorado School of Medicine 12700 E. 19th Avenue, Mail Stop B168, 
      Aurora, CO 80045, USA.
FAU - Franco-Paredes, Carlos
AU  - Franco-Paredes C
AD  - University of Colorado School of Medicine 12700 E. 19th Avenue, Mail Stop B168, 
      Aurora, CO 80045, USA.
FAU - Hawkins, Kellie L
AU  - Hawkins KL
AD  - University of Colorado School of Medicine 12700 E. 19th Avenue, Mail Stop B168, 
      Aurora, CO 80045, USA.
AD  - Denver Public Health, Denver Public Health, 605 Bannock St. Pavilion H, Denver, 
      CO 80204, USA.
LA  - eng
PT  - Case Reports
DEP - 20191122
PL  - Netherlands
TA  - IDCases
JT  - IDCases
JID - 101634540
PMC - PMC7093745
OTO - NOTNLM
OT  - HIV
OT  - Immune reconstitution syndrome (IRIS)
OT  - Intramedullary spinal cord lesions
OT  - Mycobacterium haemophilum
OT  - Nontuberculous mycobacterium (NTM)
COIS- None.
EDAT- 2020/04/01 06:00
MHDA- 2020/04/01 06:01
PMCR- 2019/11/22
CRDT- 2020/04/01 06:00
PHST- 2019/10/25 00:00 [received]
PHST- 2019/11/20 00:00 [revised]
PHST- 2019/11/20 00:00 [accepted]
PHST- 2020/04/01 06:00 [entrez]
PHST- 2020/04/01 06:00 [pubmed]
PHST- 2020/04/01 06:01 [medline]
PHST- 2019/11/22 00:00 [pmc-release]
AID - S2214-2509(19)30313-0 [pii]
AID - e00674 [pii]
AID - 10.1016/j.idcr.2019.e00674 [doi]
PST - epublish
SO  - IDCases. 2019 Nov 22;19:e00674. doi: 10.1016/j.idcr.2019.e00674. eCollection 
      2020.