PMID- 32229383 OWN - NLM STAT- MEDLINE DCOM- 20200710 LR - 20200710 IS - 1879-1026 (Electronic) IS - 0048-9697 (Linking) VI - 723 DP - 2020 Jun 25 TI - Informal e-waste recycling and plasma levels of non-dioxin-like polychlorinated biphenyls (NDL-PCBs) - A cross-sectional study at Agbogbloshie, Ghana. PG - 138073 LID - S0048-9697(20)31586-2 [pii] LID - 10.1016/j.scitotenv.2020.138073 [doi] AB - Informal e-waste recycling leads to a contamination of the workers with several hazardous substances, in particular heavy metals and persistent organic pollutants (POPs). Polychlorinated biphenyls (PCBs) belong to the group of POPs and are suspected to be associated with adverse health effects. In particular lower chlorinated PCBs, such as the congeners PCB 28 and PCB 52 are a marker of occupational exposure. The aim of our study was to assess the occupational PCB exposure in e-waste workers in relation to their specific recycling task (e.g. dismantling, burning). Altogether, n = 88 e-waste workers and n = 196 control subjects have been included in this study. All plasma participant's samples were evaluated for the PCB congeners PCB 28, 52, 101, 138, 153, 180 and sum of NDL-indicator congeners by human biomonitoring. A significant difference could be detected for the lower chlorinated PCB congeners (PCB 28, 52, and 101) for e-waste workers in comparison to the control group. Analyzing specific recycling tasks, workers who dismantle and those who burn e-waste showed the highest plasma levels of PCB 28 and 52. In conclusion, e-waste workers showed occupational related elevated PCB levels. Although those levels did not exceed the BAT value, workers were contaminated with PCBs during their task. Occupational health and safety measure are therefore necessary to protect the worker's health. CI - Copyright (c) 2020 Elsevier B.V. All rights reserved. FAU - Kaifie, Andrea AU - Kaifie A AD - Institute for Occupational, Social, and Environmental Medicine, Medical Faculty, RWTH Aachen University, Pauwelsstrasse 30, 52074 Aachen, Germany. Electronic address: akaifie@ukaachen.de. FAU - Schettgen, Thomas AU - Schettgen T AD - Institute for Occupational, Social, and Environmental Medicine, Medical Faculty, RWTH Aachen University, Pauwelsstrasse 30, 52074 Aachen, Germany. FAU - Bertram, Jens AU - Bertram J AD - Institute for Occupational, Social, and Environmental Medicine, Medical Faculty, RWTH Aachen University, Pauwelsstrasse 30, 52074 Aachen, Germany. FAU - Lohndorf, Katja AU - Lohndorf K AD - Institute for Occupational, Social, and Environmental Medicine, Medical Faculty, RWTH Aachen University, Pauwelsstrasse 30, 52074 Aachen, Germany. FAU - Waldschmidt, Saskia AU - Waldschmidt S AD - Institute for Occupational, Social, and Environmental Medicine, Medical Faculty, RWTH Aachen University, Pauwelsstrasse 30, 52074 Aachen, Germany. FAU - Felten, Michael K AU - Felten MK AD - Institute for Occupational, Social, and Environmental Medicine, Medical Faculty, RWTH Aachen University, Pauwelsstrasse 30, 52074 Aachen, Germany. FAU - Kraus, Thomas AU - Kraus T AD - Institute for Occupational, Social, and Environmental Medicine, Medical Faculty, RWTH Aachen University, Pauwelsstrasse 30, 52074 Aachen, Germany. FAU - Fobil, Julius N AU - Fobil JN AD - Department of Biological, Environmental and Occupational Health Sciences, School of Public Health, University of Ghana, Legon, Accra, Ghana. FAU - Kupper, Thomas AU - Kupper T AD - Institute for Occupational, Social, and Environmental Medicine, Medical Faculty, RWTH Aachen University, Pauwelsstrasse 30, 52074 Aachen, Germany. LA - eng PT - Journal Article DEP - 20200319 PL - Netherlands TA - Sci Total Environ JT - The Science of the total environment JID - 0330500 RN - 0 (Environmental Pollutants) RN - DFC2HB4I0K (Polychlorinated Biphenyls) SB - IM MH - Cross-Sectional Studies MH - *Electronic Waste MH - Environmental Pollutants/*analysis MH - Ghana MH - Humans MH - Polychlorinated Biphenyls/*analysis MH - Recycling OTO - NOTNLM OT - Agbogbloshie OT - Contamination OT - Occupational exposure OT - Persistent organic pollutants COIS- Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. EDAT- 2020/04/02 06:00 MHDA- 2020/07/11 06:00 CRDT- 2020/04/02 06:00 PHST- 2020/01/17 00:00 [received] PHST- 2020/03/13 00:00 [revised] PHST- 2020/03/18 00:00 [accepted] PHST- 2020/04/02 06:00 [pubmed] PHST- 2020/07/11 06:00 [medline] PHST- 2020/04/02 06:00 [entrez] AID - S0048-9697(20)31586-2 [pii] AID - 10.1016/j.scitotenv.2020.138073 [doi] PST - ppublish SO - Sci Total Environ. 2020 Jun 25;723:138073. doi: 10.1016/j.scitotenv.2020.138073. Epub 2020 Mar 19.