PMID- 32232671
OWN - NLM
STAT- MEDLINE
DCOM- 20201026
LR  - 20201026
IS  - 1534-3170 (Electronic)
IS  - 1523-3782 (Linking)
VI  - 22
IP  - 5
DP  - 2020 Mar 30
TI  - High-Sensitivity Troponins in Cardiovascular Disease.
PG  - 30
LID - 10.1007/s11886-020-01279-0 [doi]
AB  - Each new troponin assay generation is more sensitive, with recent generation 
      high-sensitivity troponin (hsTn) assays able to detect minimal myocardial injury, 
      even in asymptomatic patients. PURPOSE OF THE REVIEW: We reviewed recent 
      information on the use of hsTn assays for assessing acute and chronic 
      cardiovascular disease. RECENT FINDINGS: hsTn is used for early emergency 
      department diagnosis, accelerating early discharge with a low event rate 
      comparable if not better than current strategies. Low levels of hsTn are detected 
      in a variety of chronic cardiac and non-cardiac conditions, non-disease 
      conditions including heart failure, chemotherapy, and others. These elevations 
      identify a population at increased risk for long-term cardiovascular events. 
      However, management strategies remain unclear. hsTn has substantial advantages in 
      emergency department use. They hold promise for identifying subclinical cardiac 
      disease, with the potential for earlier intervention with the possibility of 
      decreasing disease progression. Additional studies, however, are needed to 
      determine if this strategy will lead to improved outcomes.
FAU - Kontos, Michael C
AU  - Kontos MC
AD  - Pauley Heart Center, Virginia Commonwealth University, Room 285 Gateway Building, 
      2nd floor Gateway, 1200 E Marshall St, PO Box 980051, Richmond, VA, 23298-0051, 
      USA. mckontos@vcu.edu.
FAU - Turlington, Jeremy S
AU  - Turlington JS
AD  - Pauley Heart Center, Virginia Commonwealth University, Room 285 Gateway Building, 
      2nd floor Gateway, 1200 E Marshall St, PO Box 980051, Richmond, VA, 23298-0051, 
      USA.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20200330
PL  - United States
TA  - Curr Cardiol Rep
JT  - Current cardiology reports
JID - 100888969
RN  - 0 (Biomarkers)
RN  - 0 (Troponin)
SB  - IM
MH  - Biomarkers/blood
MH  - Cardiovascular Diseases/blood/*diagnosis
MH  - Emergency Service, Hospital
MH  - Heart Failure/blood/*diagnosis
MH  - Humans
MH  - Myocardial Infarction/blood/*diagnosis
MH  - Sensitivity and Specificity
MH  - Troponin/*blood
OTO - NOTNLM
OT  - Acute myocardial infarction
OT  - Congestive heart failure
OT  - Diagnosis
OT  - Emergency department
OT  - High-sensitivity troponin
OT  - Myocardial injury
EDAT- 2020/04/02 06:00
MHDA- 2020/10/27 06:00
CRDT- 2020/04/02 06:00
PHST- 2020/04/02 06:00 [entrez]
PHST- 2020/04/02 06:00 [pubmed]
PHST- 2020/10/27 06:00 [medline]
AID - 10.1007/s11886-020-01279-0 [pii]
AID - 10.1007/s11886-020-01279-0 [doi]
PST - epublish
SO  - Curr Cardiol Rep. 2020 Mar 30;22(5):30. doi: 10.1007/s11886-020-01279-0.