PMID- 32232791
OWN - NLM
STAT- MEDLINE
DCOM- 20201231
LR  - 20210503
IS  - 1432-1084 (Electronic)
IS  - 0938-7994 (Linking)
VI  - 30
IP  - 8
DP  - 2020 Aug
TI  - Cardiovascular magnetic resonance-derived myocardial strain in asymptomatic heart 
      transplanted patients and its correlation with late gadolinium enhancement.
PG  - 4337-4346
LID - 10.1007/s00330-020-06763-3 [doi]
AB  - OBJECTIVES: To investigate whether cardiovascular magnetic resonance 
      (CMR)-derived myocardial strains were abnormal in asymptomatic heart transplant 
      (HT) patients with normal left ventricular ejection fraction (LVEF) and to detect 
      the relationship between CMR-derived myocardial strain parameters and late 
      gadolinium enhancement (LGE) in asymptomatic HT patients. METHODS: A total of 72 
      HT patients and 35 healthy volunteers underwent 1.5-T MR scanning. The 
      examination protocol included basic cine imaging and LGE. The deformation 
      registration algorithm (DRA) and feature tracking (FT) software were used for the 
      strain analyses. Myocardial strain measurements included left ventricular global 
      longitudinal strain (LVGLS), LV global circumferential strain (LVGCS), LV global 
      radial strain (LVGRS) and right ventricular longitudinal strain (RVLS). RESULTS: 
      Compared with healthy volunteers, HT patients had significantly decreased DRA- 
      and FT- derived myocardial strain measurements (all p < 0.05). There was a 
      significant correlation and high reproducibility between the DRA- and FT-derived 
      strain parameters. Both CMR-derived LVGLS and LVGRS were significantly related to 
      the presence of LGE, and multivariate logistic regression analyses showed that 
      the LVGLS measurement obtained from both techniques was independently associated 
      with the presence of LGE. The odds ratios (ORs) for DRA- and FT-LVGLS were 1.340 
      and 1.342, respectively. CONCLUSIONS: Asymptomatic HT patients with preserved 
      LVEF exhibited reduced myocardial strain parameters. The CMR-derived LVGLS was 
      independently related to the presence of LGE in HT patients. KEY POINTS: * 
      Reduced myocardial strain parameters were found in asymptomatic heart 
      transplanted (HT) patients with normal left ventricular ejection fraction (LVEF). 
      * The deformation registration algorithm (DRA) and feature tracking (FT)-derived 
      strains in asymptomatic HT patients had high reproducibility. * DRA- and 
      FT-derived LVGLS had an independent relationship with late gadolinium enhancement 
      (LGE) in asymptomatic HT patients.
FAU - Shen, Xuehua
AU  - Shen X
AD  - Department of Radiology, Union Hospital, Tongji Medical College, Huazhong 
      University of Science and Technology, Wuhan, 430022, China.
FAU - Yuan, Yating
AU  - Yuan Y
AD  - Department of Radiology, Union Hospital, Tongji Medical College, Huazhong 
      University of Science and Technology, Wuhan, 430022, China.
FAU - Yang, Ming
AU  - Yang M
AD  - Department of Radiology, Union Hospital, Tongji Medical College, Huazhong 
      University of Science and Technology, Wuhan, 430022, China.
FAU - Wang, Jing
AU  - Wang J
AD  - Department of Radiology, Union Hospital, Tongji Medical College, Huazhong 
      University of Science and Technology, Wuhan, 430022, China.
FAU - Sun, Wei
AU  - Sun W
AD  - Department of Ultrasound, Union Hospital, Tongji Medical College, Huazhong 
      University of Science and Technology, Wuhan, 430022, China.
FAU - Xie, Mingxing
AU  - Xie M
AD  - Department of Ultrasound, Union Hospital, Tongji Medical College, Huazhong 
      University of Science and Technology, Wuhan, 430022, China.
FAU - Zhang, Li
AU  - Zhang L
AD  - Department of Ultrasound, Union Hospital, Tongji Medical College, Huazhong 
      University of Science and Technology, Wuhan, 430022, China.
FAU - Zhou, Xiaoyue
AU  - Zhou X
AD  - MR Collaboration, Siemens Healthineers Ltd., Shanghai, 200000, China.
FAU - Liang, Bo
AU  - Liang B
AD  - Department of Radiology, Union Hospital, Tongji Medical College, Huazhong 
      University of Science and Technology, Wuhan, 430022, China. xiehelb@sina.com.
LA  - eng
GR  - Grant No. 81701653/National Natural Science Foundation of China/
PT  - Journal Article
DEP - 20200331
PL  - Germany
TA  - Eur Radiol
JT  - European radiology
JID - 9114774
RN  - 0 (Contrast Media)
RN  - AU0V1LM3JT (Gadolinium)
SB  - IM
MH  - Adult
MH  - Asymptomatic Diseases
MH  - Case-Control Studies
MH  - Contrast Media
MH  - Female
MH  - Gadolinium
MH  - Heart
MH  - *Heart Transplantation
MH  - Heart Ventricles/*diagnostic imaging/physiopathology
MH  - Humans
MH  - Logic
MH  - Magnetic Resonance Imaging, Cine/methods
MH  - Male
MH  - Middle Aged
MH  - Multivariate Analysis
MH  - Myocardium
MH  - Reproducibility of Results
MH  - Stroke Volume
MH  - Ventricular Dysfunction, Left/*diagnostic imaging/physiopathology
MH  - Ventricular Dysfunction, Right/*diagnostic imaging/physiopathology
MH  - Ventricular Function, Left
OTO - NOTNLM
OT  - Fibrosis
OT  - Heart transplantation
OT  - Magnetic resonance imaging
OT  - Myocardial contraction
EDAT- 2020/04/02 06:00
MHDA- 2021/01/01 06:00
CRDT- 2020/04/02 06:00
PHST- 2019/11/09 00:00 [received]
PHST- 2020/02/19 00:00 [accepted]
PHST- 2020/02/16 00:00 [revised]
PHST- 2020/04/02 06:00 [pubmed]
PHST- 2021/01/01 06:00 [medline]
PHST- 2020/04/02 06:00 [entrez]
AID - 10.1007/s00330-020-06763-3 [pii]
AID - 10.1007/s00330-020-06763-3 [doi]
PST - ppublish
SO  - Eur Radiol. 2020 Aug;30(8):4337-4346. doi: 10.1007/s00330-020-06763-3. Epub 2020 
      Mar 31.