PMID- 32238516 OWN - NLM STAT- MEDLINE DCOM- 20210823 LR - 20211203 IS - 1499-2752 (Electronic) IS - 0315-162X (Print) IS - 0315-162X (Linking) VI - 47 IP - 12 DP - 2020 Dec 1 TI - Utility of the Brief Illness Perception Questionnaire to Monitor Patient Beliefs in Systemic Vasculitis. PG - 1785-1792 LID - 10.3899/jrheum.190828 [doi] AB - OBJECTIVE: To assess the validity and clinical utility of the Brief Illness Perception Questionnaire (BIPQ) to measure illness perceptions in multiple forms of vasculitis. METHODS: Patients with giant cell arteritis (GCA), Takayasu arteritis (TA), antineutrophil cytoplasmic antibody-associated vasculitis (AAV), and relapsing polychondritis (RP) were recruited into a prospective, observational cohort. Patients independently completed the BIPQ, Multidimensional Fatigue Inventory (MFI), Medical Outcomes Study 36-item Short Form survey (SF-36), and a patient global assessment (PtGA) at successive study visits. Physicians concurrently completed a physician global assessment (PGA) form. Illness perceptions, as assessed by the BIPQ, were compared to responses from the full-length Revised Illness Perception Questionnaire (IPQ-R) and to other clinical outcome measures. RESULTS: There were 196 patients (GCA = 47, TA = 47, RP = 56, AAV = 46) evaluated over 454 visits. Illness perception scores in each domain were comparable between the BIPQ and IPQ-R (3.28 vs 3.47, P = 0.22). Illness perceptions differed by type of vasculitis, with the highest perceived psychological burden of disease in RP. The BIPQ was significantly associated with all other patient-reported outcome measures (rho = |0.50-0.70|, P < 0.0001), but did not correlate with PGA (rho = 0.13, P = 0.13). A change in the BIPQ composite score of >/= 7 over successive visits was associated with concomitant change in the PtGA. Change in the MFI and BIPQ scores significantly correlated over time (rho = 0.38, P = 0.0008). CONCLUSION: The BIPQ is an accurate and valid assessment tool to measure and monitor illness perceptions in patients with vasculitis. Use of the BIPQ as an outcome measure in clinical trials may provide complementary information to physician-based assessments. FAU - Schwartz, Mollie N AU - Schwartz MN AD - M.N. Schwartz, BS, M.A. Ferrada, MD, K.B. Gribbons, BS, J.S. Rosenblum, BS, W. Goodspeed, RN, E. Novakovich, RN, P.C. Grayson, MD, MSc, Systemic Autoimmunity Branch, National Institutes of Health (NIH), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), Bethesda, Maryland. FAU - Rimland, Casey A AU - Rimland CA AUID- ORCID: 0000-0002-5187-6921 AD - C.A. Rimland, PhD, Systemic Autoimmunity Branch, NIH, NIAMS, Bethesda, Maryland, and University of North Carolina at Chapel Hill School of Medicine, Medical Scientist Training Program, Chapel Hill, North Carolina. FAU - Quinn, Kaitlin A AU - Quinn KA AD - K.A. Quinn, MD, Systemic Autoimmunity Branch, NIH, NIAMS, Bethesda, Maryland, and Division of Rheumatology, MedStar Georgetown University Hospital, Washington, D.C., USA. FAU - Ferrada, Marcela A AU - Ferrada MA AD - M.N. Schwartz, BS, M.A. Ferrada, MD, K.B. Gribbons, BS, J.S. Rosenblum, BS, W. Goodspeed, RN, E. Novakovich, RN, P.C. Grayson, MD, MSc, Systemic Autoimmunity Branch, National Institutes of Health (NIH), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), Bethesda, Maryland. FAU - Gribbons, K Bates AU - Gribbons KB AD - M.N. Schwartz, BS, M.A. Ferrada, MD, K.B. Gribbons, BS, J.S. Rosenblum, BS, W. Goodspeed, RN, E. Novakovich, RN, P.C. Grayson, MD, MSc, Systemic Autoimmunity Branch, National Institutes of Health (NIH), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), Bethesda, Maryland. FAU - Rosenblum, Joel S AU - Rosenblum JS AD - M.N. Schwartz, BS, M.A. Ferrada, MD, K.B. Gribbons, BS, J.S. Rosenblum, BS, W. Goodspeed, RN, E. Novakovich, RN, P.C. Grayson, MD, MSc, Systemic Autoimmunity Branch, National Institutes of Health (NIH), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), Bethesda, Maryland. FAU - Goodspeed, Wendy AU - Goodspeed W AD - M.N. Schwartz, BS, M.A. Ferrada, MD, K.B. Gribbons, BS, J.S. Rosenblum, BS, W. Goodspeed, RN, E. Novakovich, RN, P.C. Grayson, MD, MSc, Systemic Autoimmunity Branch, National Institutes of Health (NIH), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), Bethesda, Maryland. FAU - Novakovich, Elaine AU - Novakovich E AD - M.N. Schwartz, BS, M.A. Ferrada, MD, K.B. Gribbons, BS, J.S. Rosenblum, BS, W. Goodspeed, RN, E. Novakovich, RN, P.C. Grayson, MD, MSc, Systemic Autoimmunity Branch, National Institutes of Health (NIH), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), Bethesda, Maryland. FAU - Grayson, Peter C AU - Grayson PC AD - M.N. Schwartz, BS, M.A. Ferrada, MD, K.B. Gribbons, BS, J.S. Rosenblum, BS, W. Goodspeed, RN, E. Novakovich, RN, P.C. Grayson, MD, MSc, Systemic Autoimmunity Branch, National Institutes of Health (NIH), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), Bethesda, Maryland; peter.grayson@nih.gov. LA - eng GR - Z99 AR999999/ImNIH/Intramural NIH HHS/United States PT - Journal Article PT - Observational Study PT - Research Support, N.I.H., Intramural DEP - 20200401 PL - Canada TA - J Rheumatol JT - The Journal of rheumatology JID - 7501984 SB - IM MH - Adult MH - Female MH - *Giant Cell Arteritis MH - Humans MH - Male MH - Middle Aged MH - Perception MH - Prospective Studies MH - Surveys and Questionnaires MH - *Takayasu Arteritis PMC - PMC7529645 MID - NIHMS1578276 OTO - NOTNLM OT - Takayasu arteritis OT - cohort studies OT - giant cell arteritis OT - vasculitis COIS- The authors declare no conflicts of interest. EDAT- 2020/04/03 06:00 MHDA- 2021/08/24 06:00 PMCR- 2021/12/01 CRDT- 2020/04/03 06:00 PHST- 2020/03/18 00:00 [accepted] PHST- 2020/04/03 06:00 [pubmed] PHST- 2021/08/24 06:00 [medline] PHST- 2020/04/03 06:00 [entrez] PHST- 2021/12/01 00:00 [pmc-release] AID - jrheum.190828 [pii] AID - 10.3899/jrheum.190828 [doi] PST - ppublish SO - J Rheumatol. 2020 Dec 1;47(12):1785-1792. doi: 10.3899/jrheum.190828. Epub 2020 Apr 1.