PMID- 32241971
OWN - NLM
STAT- MEDLINE
DCOM- 20200514
LR  - 20221207
IS  - 0042-465X (Print)
IS  - 0042-465X (Linking)
VI  - 136
IP  - 1
DP  - 2020
TI  - [Experimental justification of the use of a polymeric implant in reconstructive 
      and regenerative surgery of the sclera and tarsal plate].
PG  - 65-72
LID - 10.17116/oftalma202013601165 [doi]
AB  - INTRODUCTION: Congenital and acquired diseases, as well as traumatic injuries of 
      the sclera and tarsal plate can lead to serious complications up to the complete 
      loss of visual functions and loss of the eye as an organ if not treated timely. 
      Due to that, it becomes necessary to use biological and synthetic materials 
      during reconstructive and regenerative surgeries to replace the defects and 
      reinforce the carcass properties of the sclera and tarsal plate. PURPOSE: To 
      compare experimental and morphological features of the response of the eye and 
      surrounding tissues to implantation of the synthetic polymeric implant for 
      reconstructive and regenerative surgery (PERRS) 'Reperen-6' and biological 
      xenopericardium implant taken from cattle on the sclera in animal experiment. 
      MATERIAL AND METHODS: The studies were conducted on 12 chinchilla rabbits. PERRS 
      'Reperen-6' was implanted on the surface of the sclera (into the subtenon space) 
      of left eyes of 6 rabbits from the main group. Similar surgeries with biological 
      xenopericardium implant taken from cattle were performed on the left eyes of 6 
      rabbits from the comparison group. The right eyes of each animal from both groups 
      remained intact. After the surgery, we performed examination of the animals and 
      acquisition of the material (the eyes and surrounding tissue) in 16, 34 and 68 
      days. Enucleated eyes were fixed in 10% buffered formalin solution with 
      subsequent preparation of histologic specimen according to standard procedure. 
      CONCLUSION: The experimental and morphological studies showed that the 
      postoperative period went smoother in the main group of animals. Thanks to its 
      structure, PERRS 'Reperen-6' fixed tightly to the sclera and surrounding 
      structures forming a firm 'own tissue-implant' complex. The polymeric implant 
      'Reperen-6' can be recommended for reconstructive and regenerative surgeries to 
      reinforce the connective tissue structures in pathological conditions of sclera 
      and appendages of the eyes.
FAU - Gushchina, M B
AU  - Gushchina MB
AD  - Central Research Institute of Dental and Maxillofacial Surgery, 16 Timura Frunze 
      St., Moscow, Russian Federation, 119991.
FAU - Tereshchenko, A V
AU  - Tereshchenko AV
AD  - Kaluga branch of S.N. Fyodorov National Medical Research Center "MNTK "Eye 
      Microsurgery", 5 Svyatoslava Fyodorova St., Kaluga, Russian Federation, 248007.
FAU - Mal'kov, S A
AU  - Mal'kov SA
AD  - S.N. Fyodorov National Medical Research Center "MNTK "Eye Microsurgery", 59A 
      Beskudnikovsky Blvd., Moscow, Russian Federation, 127486.
FAU - Plakhotnii, M A
AU  - Plakhotnii MA
AD  - Kaluga branch of S.N. Fyodorov National Medical Research Center "MNTK "Eye 
      Microsurgery", 5 Svyatoslava Fyodorova St., Kaluga, Russian Federation, 248007.
FAU - Trifanenkova, I G
AU  - Trifanenkova IG
AD  - Kaluga branch of S.N. Fyodorov National Medical Research Center "MNTK "Eye 
      Microsurgery", 5 Svyatoslava Fyodorova St., Kaluga, Russian Federation, 248007.
LA  - rus
PT  - Journal Article
TT  - Eksperimental'noe obosnovanie ispol'zovaniia polimernogo implantata v 
      rekonstruktivno-vosstanovitel'noi khirurgii sklery i tarzal'noi plastinki.
PL  - Russia (Federation)
TA  - Vestn Oftalmol
JT  - Vestnik oftalmologii
JID - 0415216
SB  - IM
MH  - Animals
MH  - Cattle
MH  - Eyelids
MH  - Prostheses and Implants
MH  - Rabbits
MH  - *Plastic Surgery Procedures
MH  - *Sclera
OTO - NOTNLM
OT  - biological implant
OT  - eyelid injuries
OT  - progressive myopia
OT  - staphyloma
OT  - synthetic implant
OT  - tarsal plate
EDAT- 2020/04/04 06:00
MHDA- 2020/05/15 06:00
CRDT- 2020/04/04 06:00
PHST- 2020/04/04 06:00 [entrez]
PHST- 2020/04/04 06:00 [pubmed]
PHST- 2020/05/15 06:00 [medline]
AID - 10.17116/oftalma202013601165 [doi]
PST - ppublish
SO  - Vestn Oftalmol. 2020;136(1):65-72. doi: 10.17116/oftalma202013601165.