PMID- 32248743
OWN - NLM
STAT- MEDLINE
DCOM- 20211227
LR  - 20211227
IS  - 1532-2378 (Electronic)
IS  - 1049-5398 (Linking)
VI  - 32
IP  - 6
DP  - 2021 Dec
TI  - Association analysis of the ovine KAP6-1 gene and wool traits in Barki sheep.
PG  - 733-739
LID - 10.1080/10495398.2020.1749064 [doi]
AB  - Traditionally, sheep are raised in Egypt for meat and wool production. Selection 
      for higher wool quality could increase its suitability for particular processing 
      procedures in the wool industry, which maximizes the profit of the sheep 
      production enterprise. In this research, the effect of genetic polymorphisms of 
      the keratin-associated protein 6-1 (KAP6-1) on wool traits was investigated in 
      Barki sheep. Animals were genotyped by polymerase chain reaction (PCR)-single 
      strand conformation polymorphism (SSCP). Results identified a single nucleotide 
      polymorphism (rs589531301, G > C) with three genotypes (GG, GC and CC) and the 
      genotypic frequencies were 14.63, 43.82 and 41.55%, respectively. The KAP6-1 
      genotypes significantly (p > 0.05) affected greasy fleece weight (GFW; p = 0.05), 
      prickle factor (PF; p = 0.02), staple length (SL; p = 0.038), fiber diameter (FD; 
      p = 0.015), kemp score (KS; p = 0.048), greasy color grade (GCG; p = 0.037), 
      luster grade (LS; p = 0.048) and the greasy structure (GS; p = 0.038). The 
      noteworthy, animals with the CC genotype produce more wool (GFW = 1.116 kg) with 
      longer SL (9.03 cm), finer wool (FD = 24.34 mum) and higher KS compared to other 
      genotypes. The results of this report presented the KAP6-1 gene as a candidate 
      gene to improve the wool production traits in the Egyptian Barki sheep and 
      worldwide.
FAU - Sallam, Ahmed Mohamed
AU  - Sallam AM
AD  - Animal and Poultry Production, Desert Research Center, Mataria, Egypt.
FAU - Gad-Allah, Aymen Ali
AU  - Gad-Allah AA
AD  - Animal and Poultry Production, Desert Research Center, Mataria, Egypt.
FAU - Al-Bitar, Essam Mohamed
AU  - Al-Bitar EM
AD  - Animal and Poultry Production, Desert Research Center, Mataria, Egypt.
LA  - eng
PT  - Journal Article
DEP - 20200404
PL  - England
TA  - Anim Biotechnol
JT  - Animal biotechnology
JID - 9011409
RN  - 68238-35-7 (Keratins)
SB  - IM
MH  - Animals
MH  - Keratins/*genetics
MH  - *Sheep/genetics
MH  - *Wool
OTO - NOTNLM
OT  - Candidate gene
OT  - SNP
OT  - SSCP
OT  - genetic polymorphisms
OT  - industrial wool traits
EDAT- 2020/04/07 06:00
MHDA- 2021/12/28 06:00
CRDT- 2020/04/07 06:00
PHST- 2020/04/07 06:00 [pubmed]
PHST- 2021/12/28 06:00 [medline]
PHST- 2020/04/07 06:00 [entrez]
AID - 10.1080/10495398.2020.1749064 [doi]
PST - ppublish
SO  - Anim Biotechnol. 2021 Dec;32(6):733-739. doi: 10.1080/10495398.2020.1749064. Epub 
      2020 Apr 4.