PMID- 32251567 OWN - NLM STAT- MEDLINE DCOM- 20200518 LR - 20200518 IS - 1009-3591 (Print) IS - 1009-3591 (Linking) VI - 25 IP - 12 DP - 2019 Dec TI - [Reproductive toxicity of PBDE in males: Advances in studies]. PG - 1131-1134 AB - Polybrominated biphenyl ether (PBDE) is a kind of brominated aromatic hydrocarbon commonly used as a flame retardant and now considered as one of the persistent organic pollutants, which generally exists in the environment and organisms. Studies have shown that PBDEs have an endocrine disrupting effect, neurotoxicity, developmental toxicity, reproductive toxicity, and the ability of inducing reproductive toxicity in men by reducing semen quality, affecting testis germ cells and interfering with reproductive hormone levels. Although PBDEs have been banned in some countries, they do exist in our environment. Therefore, more studies are needed to reveal their potential toxicity and mechanisms, so as to monitor, predict and prevent their pollution. This review focuses on the male reproductive toxicity of PBDEs. FAU - Liu, Bei AU - Liu B AD - Department of Urology, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou 550004, China. FAU - Geng, Tian AU - Geng T AD - Department of Urology, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou 550004, China. FAU - Sun, Fa AU - Sun F AD - Department of Urology, People's Hospital of Guizhou Province, Guiyang, Guizhou 550004, China. LA - chi PT - Journal Article PT - Review PL - China TA - Zhonghua Nan Ke Xue JT - Zhonghua nan ke xue = National journal of andrology JID - 101093592 RN - 0 (Flame Retardants) RN - 0 (Halogenated Diphenyl Ethers) RN - 7REL09ZX35 (pentabromodiphenyl ether) SB - IM MH - Flame Retardants/*toxicity MH - Germ Cells/*drug effects MH - Halogenated Diphenyl Ethers/*toxicity MH - Humans MH - Male MH - Semen Analysis MH - Testis/drug effects OTO - NOTNLM OT - damage OT - male reproduction OT - poly brominated diphenyl ether OT - environment EDAT- 2020/04/07 06:00 MHDA- 2020/05/19 06:00 CRDT- 2020/04/07 06:00 PHST- 2020/04/07 06:00 [entrez] PHST- 2020/04/07 06:00 [pubmed] PHST- 2020/05/19 06:00 [medline] PST - ppublish SO - Zhonghua Nan Ke Xue. 2019 Dec;25(12):1131-1134.