PMID- 32259610
OWN - NLM
STAT- MEDLINE
DCOM- 20200731
LR  - 20200731
IS  - 1872-8227 (Electronic)
IS  - 0168-8227 (Linking)
VI  - 163
DP  - 2020 May
TI  - Risk and adverse outcomes of gestational diabetes in migrants: A population 
      cohort study.
PG  - 108128
LID - S0168-8227(20)30378-8 [pii]
LID - 10.1016/j.diabres.2020.108128 [doi]
AB  - AIMS: To evaluate the risk of gestational diabetes (GDM) and of neonatal/maternal 
      complications (macrosomia, large for gestational age (LGA), cesarean sections, 
      preterm deliveries, neonatal distress and fetal malformations) among women coming 
      from High Migration Pressure Countries (HMPC), compared to native (Italian) 
      mothers. METHODS: Risks of GDM and related neonatal/maternal complications were 
      evaluated in a cohort of 581,073 Italian compared with 105,111 HMPC women of age 
      15-45 yr, resident in Tuscany, Italy along years 2012-2017, delivering 122,652 
      singleton live births (18,596 from HMPC mothers). RESULTS: HMPC women, compared 
      to Italian ones, were at higher risk of GDM (OR: 1.586; 1.509-1.666;p < 0.0001), 
      peaking for women originating from South Asia (OR:3.0.49; 
      2.618-3.553;p < 0.0001). GDM was associated with increased risk of preterm 
      delivery and cesarean sections, while migrants, regardless of GDM, were burdened 
      by a higher risk of all considered complications. The rise in all these risks, 
      including macrosomia or LGA however, disappeared, after addition of interaction 
      term GDM x HMPC ethnicity. CONCLUSION: Compared to Italian mothers, HMPC women 
      had higher risk of GDM and of all considered adverse events. The addiction of the 
      interaction term GDM x HMPC ethnicity in the predictive model, however reversed 
      the rise in risk of all HMPC associated adverse outcomes.
CI  - Copyright (c) 2020 Elsevier B.V. All rights reserved.
FAU - Seghieri, Giuseppe
AU  - Seghieri G
AD  - Epidemiology Unit, Regional Health Agency of Tuscany, Florence, Italy. Electronic 
      address: gseghier@tin.it.
FAU - Di Cianni, Graziano
AU  - Di Cianni G
AD  - Diabetes and Metabolic Diseases Unit, Health Local Unit North-West Tuscany, 
      Livorno, Italy.
FAU - Seghieri, Marta
AU  - Seghieri M
AD  - Diabetes and Metabolic Diseases Unit, "San Giovanni di Dio" Hospital, Florence, 
      Italy.
FAU - Lacaria, Emilia
AU  - Lacaria E
AD  - Diabetes and Metabolic Diseases Unit, Health Local Unit North-West Tuscany, 
      Livorno, Italy.
FAU - Corsi, Edoardo
AU  - Corsi E
AD  - Diabetes and Metabolic Diseases Unit, Health Local Unit North-West Tuscany, 
      Livorno, Italy.
FAU - Lencioni, Cristina
AU  - Lencioni C
AD  - Diabetes and Metabolic Diseases Unit, Health Local Unit North-West Tuscany, 
      Lucca, Italy.
FAU - Gualdani, Elisa
AU  - Gualdani E
AD  - Epidemiology Unit, Regional Health Agency of Tuscany, Florence, Italy.
FAU - Voller, Fabio
AU  - Voller F
AD  - Epidemiology Unit, Regional Health Agency of Tuscany, Florence, Italy.
FAU - Francesconi, Paolo
AU  - Francesconi P
AD  - Epidemiology Unit, Regional Health Agency of Tuscany, Florence, Italy.
LA  - eng
PT  - Journal Article
DEP - 20200404
PL  - Ireland
TA  - Diabetes Res Clin Pract
JT  - Diabetes research and clinical practice
JID - 8508335
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Cohort Studies
MH  - Diabetes, Gestational/*epidemiology
MH  - Female
MH  - Humans
MH  - Infant, Newborn
MH  - Middle Aged
MH  - Pregnancy
MH  - Risk Factors
MH  - Transients and Migrants
MH  - Young Adult
OTO - NOTNLM
OT  - Cohort study
OT  - Gestational diabetes
OT  - Maternal complications
OT  - Migrants
OT  - Neonatal complications
OT  - Singleton live births
EDAT- 2020/04/08 06:00
MHDA- 2020/08/01 06:00
CRDT- 2020/04/08 06:00
PHST- 2019/10/24 00:00 [received]
PHST- 2020/02/11 00:00 [revised]
PHST- 2020/03/23 00:00 [accepted]
PHST- 2020/04/08 06:00 [pubmed]
PHST- 2020/08/01 06:00 [medline]
PHST- 2020/04/08 06:00 [entrez]
AID - S0168-8227(20)30378-8 [pii]
AID - 10.1016/j.diabres.2020.108128 [doi]
PST - ppublish
SO  - Diabetes Res Clin Pract. 2020 May;163:108128. doi: 10.1016/j.diabres.2020.108128. 
      Epub 2020 Apr 4.